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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 05/10/2026

We're highlighting this recent publication from @feinberg.northwestern.edu using #cryoEM to show how temperature and intracellular Ca²⁺ reshape the pharmacology of TRPM4. Notably, this cryoEM work was done entirely with 200kV Glacios Cryo-TEM. Paper: ter.li/86gu1evw

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 26/09/2026

Really cool #cryoET work with the Krios Cryo-TEM from the Mahamid lab - an unknown cell-surface complex discovered in situ, resolved to sub-nanometer scale, and captured in multiple functional states. Nice work!

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

Hopfner Lab @hopfnerlab.bsky.social · 24/09/2026

A new member has arrived in the institute! 🎉🔬Our new Aquilos 2 cryo-FIB has made it to our cryoEM facility! We are very excited to add this powerful technology to our structural biology toolbox. 🧊#ElectronMicroscopy @katja-lammens.bsky.social @genecenter-lmu.bsky.social @nucleate-cluster.bsky.social

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 22/09/2026

#CryoET and 3D image analysis reveals liposome size, shape, lamellarity, and drug encapsulation. This tomogram of liposomal doxorubicin particles was collected with the Glacios Cryo-TEM and segmented with Amira Software. Chat with our #cryoEM team here: ter.li/gdpxg0ts

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 16/09/2026

Our team is highlighting this publication from @drmichaelway.bsky.social and team @crick.ac.uk - beautiful #cryoET subtomogram averaging looking at the poxvirus portal complex with Krios Cryo-TEM. Full paper: ter.li/gaqwi4gi

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 11/09/2026

Here is a summer roundup of recent publications featuring data from our 120kV Talos #TEM. The versatile Talos 12 TEM platform can support a broad range of imaging needs. Want a closer look? We have some virtual demos coming up in the European time zone: ter.li/prbsampi

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

Daniel Hurdiss @danielhurdiss.bsky.social · 09/09/2026

Our first #cryoEM map from the Krios 5 recently installed at Utrecht University as part of the EMPower-funded upgrades to NeCEN. Hopefully the first of many more!

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 02/09/2026

Interested in #cryoEM but not sure where to start? Our team has put together a new introductory guide covering the fundamentals of SPA, how cryo-EM complements other structural biology techniques, and some of the most common misconceptions about getting started. Download the eBook. ter.li/ppx184cq

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 01/09/2026

Explore this compelling video featuring @shahmora.bsky.social and her team’s work on neurodegenerative disease. Powered by the Krios Cryo-TEM, #cryoEM and #cryoET are helping visualize cellular and molecular changes and uncover some of the earliest events in neurodegeneration. lnkd.in/p/gGZupgQz

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 28/08/2026

Come meet the team at #IMC21. Join an expert panel discussion on #FIBSEM on Tuesday. Find out about our nearly launched Glacios 3 for #cryoEM. And the team tells me there will be a chance to win a set of noise cancelling headphones.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 26/08/2026

Thanks to @erwright73.bsky.social for bringing the #cryoET community together at the 11th International Congress on Electron Tomography. As one of the first Krios 5 Cryo-TEM sites, @uwmadison.bsky.social shows what’s possible when great science, collaboration and innovative technology come together.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 10/08/2026

More beautiful #cryoEM animations from our team that captures Chikungunya virus assembly and budding in situ, using sub-tomogram averaging with 200 kV cryo-TEM. Original study doi.org/10.1038/s415... Learn more about our 200 kV solution Glacios 3 Cryo-TEM: ter.li/5zae4cxs

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 28/07/2026

Watch our on-demand webinar to see how researchers used 200 kV #cryoEM to uncover structural insights into cystobactamids, a promising class of antibacterial compounds, and get a look at what's new with the Glacios 3 Cryo-TEM. Watch here: ter.li/yxgo66bz

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

clairesnaylor.bsky.social @clairesnaylor.bsky.social · 24/07/2026

Unbelievable that its 2 weeks since #FEBSCongress2026 in Maastricht. @denizugurlar.bsky.social , Itziar Serna-Martin, @jefflengyeltemteam.bsky.social and I were constantly busy sharing how the latest advances in #cryoEM drive discovery in #structuralbiology, #molecularbiology and #biochemistry.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 14/07/2026

A beautiful journey through the nuclear pore complex with #cryoET - samples prepared via the Arctis Cryo-Plasma-FIB, data collected with the Glacios Cryo-TEM and segmented in Amira Software. #TeamTomo - See what’s possible with 200 kV cryo-ET: ter.li/n2a8i5po

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 07/07/2026

Check out our new poster that highlights the #cryoET workflow, from vitrification and cryo-FIB milling to 3D imaging and computational reconstruction. #TeamTomo 👉 Download the poster: ter.li/erzx0qmh

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 22/06/2026

Congratulation to @danielhurdiss.bsky.social on receiving the inaugural Sir Dave Stuart Early Career Researcher Award. Daniel's research uses #cryoEM to investigate how viruses infect cells and replicate. Proud that Thermo Fisher Scientific sponsors this award.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 10/06/2026

𝐖𝐚𝐧𝐭 𝐭𝐨 𝐞𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞 𝐭𝐡𝐞 𝐓𝐚𝐥𝐨𝐬 𝟏𝟐 𝐓𝐄𝐌 𝐥𝐢𝐯𝐞? Join an #electronmicroscopy online session with the Thermo Scientific Talos 12 TEM for a first-hand look at operation and imaging workflows. Get a practical view of how the system performs. Ask your questions during a live Q&A. Register: ter.li/wjuhcmo7

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 09/06/2026

Early 200 kV cryo-TEM resolved aldolase to 15 Å. Today, we have pushed this #cryoEM resolution dramatically further. The latest results: 8,925 images collected in 12 hours. Only ~4 hours needed to achieve the previously reported 2.1 Å resolution. Schedule a meeting with us: ter.li/p1o7k8yk

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 31/03/2026

It's a big day for our team. Excited to share the launch of the Thermo Scientific™ Glacios™ 3 Cryo-TEM, our latest 200 kV #cryoEM platform. High-performance imaging with the Thermo Scientific™ READY™ System that can lower installation time and infrastructure costs. Learn more: ter.li/alac5m

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 23/03/2026

This will be a great opportunity for those who have questions on sample prep for #cryoEM single particle analysis.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 25/02/2026

Congratulations to my colleague Jessica Heebner! If you want to see the science behind her image, "High resolution world of Chlamydomonas reinhardtii revealed by #cryoEM and deep learning segmentation" check out the paper: www.cell.com/molecular-ce...

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 24/02/2026

I'm late to share this - deadline is February 27 - nominations are now open for the Instruct-ERIC Early Career Researcher Award 2026, recognizing outstanding independent early career researchers across integrated structural biology. #cryoEM #TeamTomo ✔️ Self-nominations are welcome 👉 ter.li/q0rxge

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 19/02/2026

3D print your protein of choice if you win our raffle at #BPS2026 - submit your entry at our booth 728. Interested in a dedicated discussion on #cryoEM? Message me to schedule a meeting.

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 05/02/2026

Our software team has posted an on-demand session for an in-depth look into how data integration with CryoFlow Software improves #cryoEM workflow efficiency. Topics include: Live Export for real-time pipeline transfer and Advanced Reporting options. 👉 ter.li/th3mor

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 03/02/2026

Want to talk #cryoEM at #BPS2026? The Thermo Fisher Scientific team will be there. Message me if you’d like to set up a meeting. Join us at our tech showcase, Feb. 23, 2:30–4:00 p.m. for drinks and our newest product news. 👉 ter.li/qbeku7

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

Dr. Jay @joalltogether.bsky.social · 28/01/2026

Take a gander at how we load a frozen grid with vitrified sample into the Gatan Elsa CryoHolder for our Talos L120C system. One of the toughest training aspects for CryoEM is teaching the fine motor skills to manipulate your sample safely. #ElectronMicroscopy #CryoEM #Elsa #Science #Gatan

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 27/01/2026

Hi #cryoEM - The Thermo Fisher Scientific software team has opened their 2026 feedback survey for #EPU, Tomography 5, and more. ⏱️ ≤20 min, skip what’s not relevant. All experience levels welcome! Help us prioritize future developments and improvements: 👉 forms.office.com/pages/respon...

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

clairesnaylor.bsky.social @clairesnaylor.bsky.social · 23/01/2026

WEBINAR: Dr. Danielle Grotjahn, Scripps Research discusses how #cryoET shapes our understanding of cellular architecture, and analyzing data to extract quantitative insights: 10 Feb, 5 PM CET | 11 Feb, 5 AM CET Register here: ter.li/zfiv48 #CellBiology #StructuralBiology #ElectronMicroscopy

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 23/01/2026

Love this #cryoEM in this @nature.com publication looking at a previously uncharacterized clade of Cas nucleases. #Glacios 200kV cryo-TEM giving beautiful image contrast to solve the (relatively) small asymmetric protein even in the presence of glycerol. www.nature.com/articles/s41...

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 19/01/2026

We’re excited to highlight the work from @priyamvada-acharya.bsky.social and team at the Duke Human Vaccine Institute. Bringing #cryoEM into the wet lab helps their team move faster, train more users, and collaborate more effectively. Full video: ter.li/31snmd

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 15/01/2026

Congratulations to the team and their work that made the cover of Molecular Cell. A massive, open #cryoET dataset that captures molecular organization inside intact cells and pushes what’s possible for visual proteomics, method development, and computational reuse. 👉 ter.li/of4cgh

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 13/01/2026

Our team will be at the #StructureBasedDrugDesignSummit February 3-5 in San Diego! Chat me and I can put you touch to set up a meeting. Meanwhile, explore #cryoEM structure-based drug design #sbdd webinars, case studies, posters, and more. 👉 ter.li/0r4bhl

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Reposted by Jeff Lengyel & TEM Team at Thermo Fisher Scientific

Oliver Raschdorf @oraxdrf.bsky.social · 03/01/2026

Very proud to be part of this project! This not only is the (nominally) highest resolution non-ApoF cryoEM structure, but also for the first time resolved a ligand and structural hetetogeneity in that resolution range, giving new insights into the Rubisco enzyme mechanism. A nice start for Krios 5!

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 07/01/2026

Fragment-based drug discovery #FBDD is increasingly viable for membrane proteins using high-throughput #cryoEM. This blog covers cryoEM fragment screening workflows, resolution/occupancy needs for low-MW ligands, and technology advances for structure-guided #drugdiscovery. 👉 ter.li/73g8yx

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 17/12/2025

From our software team - #SmartEPU Software v3.14 for #SingleParticleAnalysis. This release gives #cryoEM researchers faster workflows and smarter automation with CryoFlow 2.0. See it in action. ter.li/gfdmj7

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 10/12/2025

Our team highlighted this #cryoET work from Pitt looking at how bacteriophages fight TB. New #cryoEM work shows how phage Bxb1 attaches to the bacterial surface and delivers its DNA—promising insight for tackling antibiotic-resistant infections. #TeamTomo ter.li/fp1kwi

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 05/12/2025

Excited to see our work with 100 kV cryo-EM featured on the cover of Structure! 📄 Check out the paper here: ter.li/8vfd97 #CryoEM #ElectronMicroscopy #StructuralBiology

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 24/07/2025

Will you be at M&M in Salt Lake City? Come talk to us about Talos 12 TEM - just launched this week, this is the next step in our 120 kV instrumentation, designed to fit your #electronmicroscopy needs. Learn more ter.li/sgthu8

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Jeff Lengyel & TEM Team at Thermo Fisher Scientific @jefflengyeltemteam.bsky.social · 22/07/2025

Our first post on Bluesky! Excited to highlight some #CryoET work from Qingtao Shen's lab at SUSTech looking at #mitochondria structures in glioblastoma cells with #GlaciosCryoTEM. Read their paper here: www.pnas.org/doi/10.1073/...

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