Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.

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Costings commissioned by independent MP Monique Ryan reveal the government could double how much funding it gives to innovative health research each year.

Six researchers from the University of Adelaide and University of South Australia have been named as this year’s South Australian Young Tall Poppies.

This week the presenter turns 99. To celebrate, we asked 99 nature lovers – including Margaret Atwood, Jane Fonda, Bono, Kate Winslet and Michael Palin – how he has helped us see the world with fresh eyes

Oncogene - ITGB1/FERMT1 mechanoactivation enhances CD44 characteristic stemness in oral squamous cell carcinoma via ubiquitin-dependent CK1α degradation

British Journal of Cancer - Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes

This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...

NHMRC cancer cancer research national health and medical research

A road map to success based on Nature’s hiring-in-science survey, with advice for every stage from application to offer.

A key characteristic of cancer cells is their ability to induce changes in their microenvironment that render it permissive to tumor growth, invasion and metastasis. Indeed, these changes are require....

Single-cell DNA sequencing identifies recurrent copy number changes in healthy breast tissue from women with wild-type or germline BRCA1 or BRCA2 mutations.

Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...

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