YouTube video by CCP-EM

Using single particle cryo-EM on plaque-mimicking nanodiscs, researchers determined multiple connexin assembly states and uncovered lipid-protein interactions that may help understand gap junction org...

How to make use of one-click, automated data processing workflows that can provide equal or better results as manual processing

Processing EMPIAR-10927 including separating targets using Per-particle scales or custom settings in Ab-Initio Reconstruction, and using 3DVA to guide sub-classification choices.

He, Teng and Yang et al. report how metformin, the widely used antidiabetic drug, inhibit its target, the respiratory complex I, through a distinct state-dependent, inhibitor trapping mechanism, thus ...

How Cryo-EM allows a closer look at the Human neutralizing antibodies targeting the measles virus

High-Resolution Ab-Initio Reconstruction: Extending Cryo-EM to Smaller Particles with CryoSPARC™

YouTube video by Structura Biotechnology Inc.

Learn the fundamentals of cryo-EM Single Particle Analysis (SPA) in this Cryo-EM Essentials introductory mini-course.