PhD Project - Redox Control of RNA Splicing in Cardiovascular Disease at University of Dundee, listed on FindAPhD.com

A greater genetic susceptibility has been proposed as an explanation of the greater rates of cardiovascular and metabolic disease in South Asian relative to European populations. We first demonstrate ...

This Collection calls for papers that investigate the expanding clinical and biological roles of GLP‑1 RAs. We welcome studies that examine the mechanisms ...

The NHGRI-EBI GWAS Catalog: a curated collection of all published genome-wide association studies, produced by a collaboration between EMBL-EBI and NHGRI

The Medical Research Council (MRC) unpauses curiosity driven research funding and improves the funding process.

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenge...

Aims/hypothesis The role of intra-pancreatic lipid and collagen in type 2 diabetes pathogenesis remains unclear. We sought to examine this in pancreases from organ donors with and without diabetes. Me...

Apply your computational and mathematical skills to solving the hardest problems in big-data genomics and have a wide impact on science and clinical practice, including diabetes and related...

Many Mendelian randomization (MR) papers have been conducted only in people of European ancestry, limiting transportability of results to the global population. Expanding MR to diverse ancestry groups...

AbstractBackground and Aims. Cardiovascular ageing is a progressive loss of physiological reserve, modified by environmental and genetic risk factors, that

Dzando et al. identify locally relevant frailty thresholds for older people in Sub-Saharan Africa through Receiver Operating Characteristic analysis and random-effects meta-analysis. Findings demonstrate variability in population level thresholds with a pooled threshold of 0.29 demonstrating good sensitivity and specificity across the populations.

Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

Genes and Health (G&H) is a biomedical study of adult British-Pakistani and -Bangladeshi research volunteers enriched for autozygosity. We performed whole exome sequencing in 44,028 G&H participants, ...

Opposition to Trump administration and fears of customs run-ins are shifting travel plans

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New study finds genetic links to how and when South Asian populations develop diabetes

New study reveals genetic drivers of early onset type 2 diabetes in South Asians  A genetic predisposition to having lower insulin production and less…

A precision medicine approach used unsupervised clustering to identify five distinct phenotypic profiles that can better predict risks of cardiometabolic disease compared with those ascertained based ...

Nature - There is growing evidence from metagenome-wide association studies that several common human disorders, such as type 2 diabetes mellitus (T2D), are associated with intestinal dysbiosis, an...