StructureMASST enables pan-repository MS/MS searches using a chemical name or structure.

A quiet policy change means the government is making fewer bets on long-term science.

Critical Thinking AI for constructive criticism and science evaluation

With the exception of molecules acquired through the lungs, skin absorption, or part of a medication regime, nearly all molecules in our bodies origin…

With the exception of molecules acquired through the lungs, skin absorption, or part of a medication regime, nearly all molecules in our bodies origin…

Samples could provide an objective measure of diets and help to unravel their contribution to disease.

A graduate student from southeast Asia, now based in a European country and missing her homeland, agonizes over her next career move.

Mediation analysis has gotten a lot of flak, including classic titles such as “Yes, but what’s the mechanism? (Don’t expect an easy answer)” (Bullock et al., 2010), “What mediation analysis can (not) ...

Nature Metabolism, Published online: 28 February 2025; doi:10.1038/s42255-025-01239-4Discovery of metabolites prevails amid in-source fragmentation

Event organizers often overlook the visa-related difficulties that researchers in low- and middle-income countries face. This must change.

Nature Metabolism - Discovery of metabolites prevails amid in-source fragmentation

Untargeted metabolomics often produce large datasets with missing values. These missing values are derived from biological or technical factors and can undermine statistical analyses and lead to biase...

With long-term space travel and extraterrestrial habitation becoming feasible, understanding how space environmental exposures, microbial communities, and molecular profiles differ from Earth is cruci...

Abstract Phytohemagglutinin (PHA), a natural tetramer comprising PHA-E and PHA-L subunits that preferentially bind to red and white blood cells, respectively, constitutes a significant antinutrition...

Longitudinal studies are crucial for understanding complex microbiome dynamics and their link to health. We introduce TEMPoral TEnsor Decomposition (TEMPTED), a time-informed dimensionality reduction ...

Humans often assume killing will solve the problem. Here's yet another example of why we are wrong.

See year by year how vaccines beat back nine dangerous infectious diseases