Exhaustion is a functional state that hampers anti-cancer and antiviral CD8 T cell activity, and is preceded by a stem-like state, maintained by the transcription factor TCF1. Here authors develop mou...

Germinal center B cells rely on ZFP36L1 and ZFP36L2 to control cell division and avoid replication stress that leads to apoptosis.

Activated CD4 T cells become either T-helper (Th) or T-follicular helper (Tfh) cells that support cellular or humoral immunity. We have investigated how polyclonal, vaccine induced T cells in mice bif...

Dalit, Tan and colleagues provide a multiomic profile of T follicular helper (TFH) cells responses to diverse pathogens, revealing a blueprint for transcriptional flexibility and new tools to interrog...

You have to enable JavaScript in your browser's settings in order to use the eReader.

RNA binding proteins have been shown to alter the function of various immune cells. Here the authors show that ZFP36-family RNA binding proteins play an important role in regulatory T cells to maintai...

Ribosomes cooperate through transient collisions to ensure efficient translation.