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EvoMG Program

@evomg-bcn.bsky.social
352 followers 214 following 93 posts

The Evolutionary Medical Genomics (EvoMG) Program is a joint initiative by the CRG, UPF and IBE in Barcelona to boost biomedical research by applying evolutionary approaches. Website: t.co/MBCtzyi8jt

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Reposted by EvoMG Program
Barbara Marte @barbmarte.bsky.social · 22/07/2026
new out in Nature www.nature.com/articles/s41...
nature.com
Genetic background sets the trajectory of experimental cancer evolution - Nature
Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stage...
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Reposted by EvoMG Program
Max Stammnitz @maxstammnitz.bsky.social · 22/07/2026
Wow! A fourth class of transmissible cancers. CONTAGIOUS FISH MELANOMA, discovered in Lake Memphremagog (Vermont / Quebec) 🎣 🧬 😷 www.nature.com/articles/s41... @uvmvermont.bsky.social
nature.com
Brown bullhead catfish melanoma represents a novel transmissible cancer - Nature
Whole-genome sequencing analysis of tumour and matched non-tumour host tissues of the brown bullhead catfish reveals a type of naturally occurring transmissible cancer.
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EvoMG Program @evomg-bcn.bsky.social · 01/06/2026
We had a great seminar by Duncan Odom @odomlab.bsky.social today about mutagenesis and cancer evolution!
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Reposted by EvoMG Program
Centre de Regulació Genòmica (CRG) @crg.eu · 31/05/2026
Huge congrats to the CRG's Mafalda Dias for being one of eight finalists for the 2026 Premio Vanguardia de la Ciencia, one of Spain's most visible science prizes. Voting is open now and closes on Sunday 28 June at 23:59 (peninsular time).
lavanguardia.com
La IA mejora el estudio de las enfermedades raras
Vota a las finalistas del premio Vanguardia de la Ciencia
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Reposted by EvoMG Program
EVOMG-Doctoral Network @evomg-dn.bsky.social · 09/04/2026
We’ve reopened the call for a PhD position with Juana Diez at @melisupf.bsky.social within the EVOMG-DN project. 🧬 Viral Codon Usage: A Novel Readout of Virus Evolution and Host Interaction 🗓 Deadline: 10 May 2026 👉 Apply here: www.evomg-dn.eu/call-for-app...
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Reposted by EvoMG Program
The EMBO Journal @embojournal.org · 27/02/2026
Molecular #evolution of animal #aging: A field perspective explores the impact of evolution on aging and offers a multi-angle view on longevity variation across model organisms and environments link.springer.com/article/10.1...
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Reposted by EvoMG Program
Jonathan Frazer @jonnyfrazer.bsky.social · 24/11/2025
popEVE is out in Nature Genetics! 🎉 We built a proteome-wide model that combines cross-species and human population variation to rank missense variants by disease severity and help diagnose rare genetic disorders. rdcu.be/eRu7K
rdcu.be
Proteome-wide model for human disease genetics
Nature Genetics - popEVE is a proteome-wide deep generative model to identify and predict pathogenicity of missense mutations causing genetic disorders.
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Reposted by EvoMG Program
Debora Marks @deboramarks.bsky.social · 24/11/2025
New paper “Proteome-wide model for human disease genetics” is now live at Nature Genetics: rdcu.be/eRu7K popEVE (pop.evemodel.org) finds the needles in the haystacks of human genetic variation:
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 13/11/2025
Meet our EvoMG-DN PI, Jonas Juan-Mateu from @melisupf.bsky.social -Barcelona Interested in joining the network? Find out more about the PhD programme → www.evomg-dn.eu #PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope
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UPF Medicine and Life Sciences @melisupf.bsky.social · 14/11/2025
Hey, thanks to the @evomg-dn.bsky.social you can join the Developmental and Evolutionary Transcriptomics Laboratory led by Manuel Irimia ( @mirimiam.bsky.social ) with Jonàs Juan as PI to develop your PhD exploring the molecular adaptation of pancreatic islets. 🧬🦇 #PhDOffer #AcademicJobs @crg.eu
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Reposted by EvoMG Program
EVOMG-Doctoral Network @evomg-dn.bsky.social · 14/11/2025
🚨 15 days left to apply! Be part of EvoMG-DN and advance your PhD career in evolutionary genomics. 👉 www.evomg-dn.eu #PhD #DoctoralTraining #ResearchCareers #LifeSciences #BiomedicalResearch #Genomics #EvolutionaryBiology #MSCA #HorizonEurope #EUResearch #ResearchOpportunities #PhDPositions
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EvoMG Program @evomg-bcn.bsky.social · 05/11/2025
Today we had a great EvoMG Seminar by Dario Valenzano @dvalenzano.bsky.social from FLI, who told us about some of their recent aging work using the fascinating short-lived killifish. Hosted by @mirimiam.bsky.social evomedgenomics.com/events/exter...
Dario Valenzano at PRBB
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Reposted by EvoMG Program
EvMedASU @evmedasu.bsky.social · 04/11/2025
1. Map evolutionary diversity to hack biomedical innovation 2. Revolutionize cancer therapy 3. Target the development of antimicrobial resistance 4. Address Anthropocene-related diseases 5. Support healthier behaviors 6. Improve pandemic responses by Barbara Natterson-Horowitz & Dan Blumstein!
weforum.org
6 ways evolutionary medicine can transform our health
Evolutionary medicine is an emerging interdisciplinary field with huge potential to improve human health and tackle a broad scope of major health challenges.
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Reposted by EvoMG Program
The Institute of Cancer Research @icr.ac.uk · 23/10/2025
“Although drug resistance closes some doors, it can open new ones.” In exciting research, our scientists have found that a recently discovered vulnerability in soft tissue sarcomas could pave the way for smarter, more adaptive treatment strategies that extend and save more lives.
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Centre de Regulació Genòmica (CRG) @crg.eu · 23/10/2025
Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...
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Reposted by EvoMG Program
UPF Medicine and Life Sciences @melisupf.bsky.social · 17/10/2025
#PhDOffer #AcademicJobs #PhDChat #PhDLife 📣 15 fully funded PhD positions in Evolutionary Medical Genomics (@evomg-bcn.bsky.social) are open! 🧬🔬 Explore ageing, cancer evolution, and pathogen resistance across leading European institutions. Deadline: Nov 30 Apply here: www.evomg-dn.eu
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 16/10/2025
Become part of a Marie Skłodowska-Curie Doctoral Network a prestigious EU initiative offering world-class research training, international experience, and strong career prospects for early-stage researchers. It’s more than a PhD:it’s a launchpad for your research career! Apply now: www.evomg-dn.eu
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Toni Gabaldón @tonigabaldon.bsky.social · 17/10/2025
Including one position in our lab to work on emerging fungal pathogens. 👇 #phD #Candida
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Servei de Recerca de la UPF @sdrecercaupf.bsky.social · 15/10/2025
At the @melisupf.bsky.social, @mirimiam.bsky.social would like to recruit two fully-funded #PhDcandidate for the #MSCA Doctoral Network @evomg-dn.bsky.social. #AcademicSky #ResearchJobs
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Reposted by EvoMG Program
Manuel Irimia @mirimiam.bsky.social · 15/10/2025
🚨🚨🚨 Two super well-funded PhD grants from our MSCA Doctoral Network @evomg-dn.bsky.social at our lab at @melisupf.bsky.social, @crg.eu and the @evomg-bcn.bsky.social Program. If you're excited about evolution, genomics and biomedical research, this is your DN! 😃 Further info: www.evomg-dn.eu and 👇
evomg-dn.eu
EVOMG-DN
EvoMG-DN is a European Doctoral Network funded by the Horizon Europe Marie Skłodowska-Curie Actions (MSCA), composed of 14 beneficiaries and associated partners from both academic and non-academic sectors.
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 13/10/2025
We’re proud to introduce the Principal Investigators leading the EvoMG Doctoral Network, an international team guiding and mentoring the next generation of evolutionary medicine researchers. Discover more about their work and the PhD opportunities 👇 www.evomg-dn.eu
@mirimiam.bsky.social, @jamie-blundell.bsky.social, @emmateeling.bsky.social
@trevorgraham.bsky.social, @eszterlakatos.bsky.social
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EVOMG-Doctoral Network @evomg-dn.bsky.social · 07/10/2025
📢 EvoMG-DN PhD applications are now open! Join our EU-funded MSCA network and explore evolution, ageing, and disease. 👉 www.evomg-dn.eu 📅 Apply by 30 November 2025 #PhD #DoctoralTraining #MSCA #HorizonEurope #Genomics #EvolutionaryBiology #BiomedicalResearch#EarlyCareerResearchers
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Trevor Graham @trevorgraham.bsky.social · 14/10/2025
The second is about potential fitness costs of cancer drug resistance, and how we might exploit them using approaches like adaptive therapy. (building on our work with @mlockley.bsky.social in ovarian cancer: aacrjournals.org/cancerres/ar...). Description here: www.icr.ac.uk/study-and-ca...
aacrjournals.org
Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control
Carboplatin adaptive therapy improves treatment efficacy without increasing daily dose due to reduced fitness of drug-resistant populations, which can be tracked using cfDNA and could direct adaptive ...
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Reposted by EvoMG Program
Trevor Graham @trevorgraham.bsky.social · 14/10/2025
We have two fantastically well-funded #PhD studentships available through the @evomg-dn.bsky.social #EU doctoral network (led by brilliant @mirimiam.bsky.social, @crg.eu). These enable students to move to the UK and come and work with us @icr.ac.uk to exploit #cancer #evolution for patient benefit.
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UPF Medicine and Life Sciences @melisupf.bsky.social · 13/10/2025
Las week, the @prbb.org hosted the Iberian EvoMG PI Meeting 2025. An event organized by the @evomg-bcn.bsky.social & @biomics-twinning.bsky.social to bring together all researchers working on the different areas of evolutionary medical genomics. Delighted to see so many familiar faces there! 🙌😊
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And last but not least, closing this very intense meeting, Jesús Perez-Losada, from iBMCC, told us about their work on molecular and genetic determinants of cancer susceptibility, evolution, and treatment response.
Jesus Perez-Losada
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Solip Park, from CNIO ( @cniostopcancer.bsky.social ), spoke about her work in context-specific cancer fitness landscapes and protein-protein interactions.
Solip Park, CNIO
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Rosa Fernández ( @rosafernandez.bsky.social ), from the EvoMG Program and @ibe-barcelona.bsky.social, gave her flash talk about genome evolution in annelids and how they could be novel models to understand genomic instability events in cancer.
Rosa Fernández, EvoMG Program, IBE-CSIC
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Then, Ferran Nadeu ( @ferrannadeu.bsky.social ), from IDIBAPS ( @idibaps.bsky.social ), told us about his work on origin and immuno-genomic forces driving multiple and independent CLL expansions.
Ferran Nadeu, IDIBAPS
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Donate Weghorn ( @weghornlab.bsky.social ), from the EvoMG Program and @crg.eu, talked about her work on mutational processes and selection in cancer.
Donate Weghorn, EvoMG Program, CRG
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And the last session of the meeting was Session 5: Cancer. The first speaker was David Posada ( @davidposada.bsky.social ), from the Universidade de Vigo and @cinbio.bsky.social, who showed us how somatic phylogenetics can provide fundamental insights into the evolutionary dynamics of cancer.
David Posada, CINBIO, U Vigo
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
In between Sessions 4 (aging) and 5 (cancer), we had the perfect bridge between the two topics, with the second keynote talk, by Iñigo Martincorena (@imartincorena.bsky.social), who told us about their work on somatic evolution, and its implications for aging and cancer.
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And the last speaker of the session was Marc de Manuel ( @marcdemanuel.bsky.social ), from the EvoMG Program and @ibe-barcelona.bsky.social presenting his work on mutation.
Marc de Manuel, EvoMG Program, IBE-CSIC
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And also from @cabd-upo-csic.bsky.social , Juan Tena, presented his lab's work on aging using killifish and a collaborative project to understand age-related retina degeneration.
Juan Tena, CSIC, CABD
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Juan Ramón Martinez Morales ( @jrmarmor.bsky.social ), from @cabd-upo-csic.bsky.social , presented their work on eye malformations and aging, and the underlying gene regulatory networks, using fish models.
Juan Ramón Martinez Morales, CSIC, CABD
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Continuing on pancreas and #diabetes, Jose Bessa from i3S ( @i3suporto.bsky.social ) presented his work on characterizing regualtory elements in zebrafish and mammals with relevance to this disease.
Jose Bessa, i3S
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Jonas Juan-Mateu, from the EvoMG Program and @melisupf.bsky.social presented his work on microexons and diabetes and the plans to investigate diet adaptations in bats.
Jonàs Juan-Mateu, EvoMG Program, UPF
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, David Comas, also from the EvoMG Program, @melisupf.bsky.social and @ibe-barcelona.bsky.social, who could not attend Session 2, presented in this session their work on adaptation to malaria of Sudanese Copts and the evolutionary history of the Roma population.
David Comas, EvoMG Program, UPF, IBE
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
The first speaker was Arcadi Navarro, from the EvoMG Program, @melisupf.bsky.social , @crg.eu, @ibe-barcelona.bsky.social, @fpmaragall.bsky.social et al, who told us how they plan to study cancer & longevity across evolution to learn about their major determinants.
Arcadi Navarro, EvoMG Program, UPF, CRG, IBE
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
The last day (Fri 10/10) started with Session 4: Aging and related diseases.
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And closing this intense session and the main day of talks, Toni Gabaldón ( @gabaldonlab.bsky.social and @tonigabaldon.bsky.social ), from BSC and IRB ( @irbbarcelona.org ), told us about their work on the evolution and pathogenicity of Candida.
Toni Gabaldón, BSC, IRB
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Tanja Dapa ( @tanjadapa.bsky.social ), from the CABD-CSIC-UPO ( @cabd-upo-csic.bsky.social ), talked about her work on bacterial evolution in the gut under different dietary regimes and potential immunological connections.
Tanja Dapa, CSIC-UPO, CABD
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Pedro José Esteves, from CIBIO, summarized their work on co-evolution of virus and host and on rabbit as an immunologic model.
Pedro José Esteves, CIBIO
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Also from IRYCIS-RyC Hospital, now Teresa Coque @tmcoque.bsky.social , told us in her flash talk about their work on transmission and adaptation of COPs in the patient-care environment.
Teresa M. Coque, IRYCIS-RyC Hospital
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Then, Val F. Lanza, from IRYCIS-RyC Hospital, talked about her tools to investigate and track bacterial infection and evolution.
Val F. Lanza, IRYCIS-RyC Hospital
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Next, Mireia Valles-Colomer ( @mireiavallesc.bsky.social ), from the EvoMG Program and @melisupf.bsky.social , talked about her work about microbiome transmission.
Mireia Valles-Colomer, EvoMG Program, UPF
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
Then, we Mireia Coscollà ( @pathogenomics.bsky.social ), from I2SysBio ( @i2sysbio.es ) talked about compatibility between hosts in bacterial infections.
Mireia Coscollà, CSIC, I2SysBio
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And after the round table, we continued Session 3 on microbes, microbiome and antibiotic resistance, with Maria Isabel Veiga, from @icvs-uminho.bsky.social , who talked about drug resistance in malaria.
Maria Isabel Veiga, ICVS
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
After the coffee break, we had a round table about dealing with evolution of drug resistance & synergies among EvoMG fields. We had a panel representing the different related "areas": Isabel Veiga (Plasmodium), David Posada (Cancer), Jero Rodriguez (Bacteria), Ana Abecasis (Virus).
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EvoMG Program @evomg-bcn.bsky.social · 12/10/2025
And just before the break, José A. Escudero ( @jaescudero.bsky.social ), from the U. Complutense de Madrid ( @ucm.es ), presented their recent work on mobile integrons.
José A. Escudero, U. Complutense de Madrid
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