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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)

@gabaldonlab.bsky.social
237 followers 78 following 39 posts

Comparative genomics group at IRB and BSC (Barcelona, Spain) cgenomics.org

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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 04/07/2026
If you are an excellent postdoctoral researcher passionate about microbe genome evolution and are interested in any research line in my group there is a #Postdoc opening in my group at BSC via AuSpire! Apply to BSC-PF1 by 7 Sept 2026: 👇 auspire.eu/research-team/bsc-pf1-call-3/
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
BIST-Barcelona Institute of Science and Technology @bist.eu · 16/06/2026
🦠 How did our cells originate? A study by @gabaldonlab.bsky.social at @irbbarcelona.org & @bsc-cns.bsky.social suggests cellular complexity emerged gradually over millions of years, rather than from a single evolutionary event. 📝 Published in @nature.com #BISTCommunity 👉 bist.eu/a-study-by-i...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 14/06/2026
Monday 15th of June at 12:30 I will be giving a talk at the Faculty of Sciences of #Tetouan (Morocco). I will be talking about our recent work on the emergence of drug resistance and new pathogenic species from environmental sources in #Candida related yeasts.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 13/06/2026
Very proud of Islam, who performed part of her thesis with us at @irbbarcelona.org . Has been a pleasure to attend the defence, and has been my first chance to visit Morocco.
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 13/06/2026
Congratulations to our new Doctor, Islam Ahaik who obtained her PhD today at the Faculty o Sciences in Tetouan.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Patricia Ruiz Guevara @patriciaenverde.bsky.social · 10/06/2026
¿De dónde venimos? El gran salto evolutivo del que surgieron las células complejas que nos conforman es un enigma. Un estudio de @irbbarcelona.org y @bsc-cns.bsky.social revela que hay más actores implicados de los que pensábamos El 'ménage à trois' celular 👉 www.elconfidencial.com/tecnologia/c...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Patricia Ruiz Guevara @patriciaenverde.bsky.social · 10/06/2026
"Entender el origen de la vida nos ayuda a explicar el mundo en que vivimos, incluida nuestra propia existencia", dice @tonigabaldon.bsky.social, autor principal del estudio. También impulsa otras investigaciones y abre la puerta a "posibilidades que no imaginamos". Los superordenadores ayudan 💻 🦠👇🏼
elconfidencial.com
Un 'ménage à trois' celular: un equipo español revoluciona lo que sabíamos del origen de la vida
El gran salto evolutivo por el que surgieron las células complejas que nos conforman sigue siendo un enigma. Una nueva investigación con el supercomputador de Barcelona revela que hay más actores implicados de los que pensábamos
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Anna Papageorgiou @apapageorgiou.bsky.social · 10/06/2026
The origin of complex cells may have been far messier than we thought!
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Lzvolk @lzvolk.bsky.social · 10/06/2026
Fantastic paper. Esp challenging the typical binary process of genesis or transition. Just as the first cells as we know them were possibly survivors of multitudes of attempts that did not survive to evolve. The origin of cellular life was not simple; neither was evolution to multiple cell types.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
STCmicrobeblog @stcmicrobeblog.bsky.social · 11/06/2026
"Thus, the prokaryotic-to-eukaryotic transition was probably a gradual and complex process, with a constant flow of HGT from diverse sources." #SymbioSky
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 11/06/2026
www.ara.cat/ciencia-medi...
ara.cat
Què som i d'on venim? Un estudi català reescriu la història de la vida complexa
Investigadors de l'IRB i el BSC reconstrueixen l'origen dels eucariotes i apunten que són fruit de donacions genètiques microbianes de milions d'anys
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Science Media Centre España @sciencemediacentre.es · 10/06/2026
🦠Un estudio español en @Nature replantea el origen de nuestras células como una historia de alianzas microbianas 🗨️Alex de Mendoza: "El proceso de formación de los eucariotas no fue una relación monógama de dos organismos, sino más tipo ménage à trois" sciencemediacentre.es/un-estudio-e...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 11/06/2026
www.elconfidencial.com/tecnologia/c...
elconfidencial.com
Un 'ménage à trois' celular: un equipo español revoluciona lo que sabíamos del origen de la vida
El gran salto evolutivo por el que surgieron las células complejas que nos conforman sigue siendo un enigma. Una nueva investigación con el supercomputador de Barcelona revela que hay más actores implicados de los que pensábamos
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Alex de Mendoza @alexdemendoza.bsky.social · 11/06/2026
Funny to get quoted on a pun about the origin of eukaryotes being a bit of a promiscuous relationship in the 🇪🇸 press, but glad to help communicate @tonigabaldon.bsky.social & his team's fatnastic work, which highlights the importance of giant viruses 👾 in eukaryotic origins @nature.com. Congrats!
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Ismael Mingarro @ismaelmingarro.bsky.social · 11/06/2026
Y si la aparición d las células eucariotas no hubiera sido tan sencilla como pensábamos? Gran trabajo @tonigabaldon.bsky.social 🙌🏻🙌🏻🙌🏻🥂🍾 www.expansion.com/directivos/e...
expansion.com
Científicos españoles describen un intrincado puzzle genético microbiano que originó la vida celular compleja
El origen y el proceso por el que surgieron las células eucariotas es aún una de las grandes preguntas de la biología desde que Lynn Margulis* propusiera que la mitocondria...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Ricard Solé @ricardsole.bsky.social · 12/06/2026
How did complex cells emerge? In this groundbreaking paper, @tonigabaldon.bsky.social & co show that eukaryotes arose through multiple waves of ancient genetic exchange involving diverse bacteria (& giant viruses!) revealing a far more complex origin than we imagined. www.nature.com/articles/s41...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
ICREA Community @icreacommunity.bsky.social · 13/06/2026
I si l'origen de les nostres cèl·lules no és com ens pensàvem? 🦠🤔 Un estudi liderat pel #RecercaireICREA @tonigabaldon.bsky.social (@irbbarcelona.org @bsc-cns.bsky.social) ha descrit el rol de bacteris i virus gegants en l’origen de les cèl·lules complexes. 👇🏼 www.lavanguardia.com/ciencia/2026...
lavanguardia.com
Descubren cómo se formó la célula de la que descienden todos los animales y plantas
Científicos de Barcelona revelan un episodio clave de la evolución de la vida en la Tierra ocurrido hace 2.000 millones de años
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Ricard Solé @ricardsole.bsky.social · 13/06/2026
This theoretical approach (previously in this @pnas.org s.org paper by @nigelgoldenfeld.bsky.social and Carl Woese www.pnas.org/doi/abs/10.1...) seems consistent with the recent work by @tonigabaldon.bsky.social on the complex paths towards the emergence of LUCA.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Mathieu M.J.E. Rebeaud @chercheurjuteux.com · 12/06/2026
Gene ancestries reveal diverse microbial associations during eukaryogenesis Fantastic paper from @microbiobits.bsky.social @tonigabaldon.bsky.social and colleagues. www.nature.com/articles/s41...
nature.com
Gene ancestries reveal diverse microbial associations during eukaryogenesis - Nature
Phylogenomic reconstruction of the proteome of the last eukaryotic common ancestor sheds light on the origin of eukaryotes, indicating an important role of horizontal transfer of genes from diverse ba...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IRB Barcelona @irbbarcelona.org · 11/06/2026
🦠 Descubren cómo se formó la célula de la que descienden todos los animales y plantas. Científicos de Barcelona revelan un episodio clave de la evolución de la vida en la Tierra ocurrido hace 2.000 millones de años. 🗞️ @lavanguardia.com ➡️ shorturl.at/iwnR0 @gabaldonlab.bsky.social
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 11/06/2026
Virus gigantes, la pieza inesperada para explicar el origen de la vida compleja theconversation.com/virus-gigant...
theconversation.com
Virus gigantes, la pieza inesperada para explicar el origen de la vida compleja
Un estudio del Barcelona Supercomputing Center desvela el origen de la vida compleja, los eucariotas, como el resultado de múltiples intercambios genéticos entre bacterias, arqueas y virus gigantes.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 10/06/2026
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IRB Barcelona @irbbarcelona.org · 10/06/2026
🦠 How did our cells originate? A study by #IRBBarcelona & @bsc-cns.bsky.social by @gabaldonlab.bsky.social, suggests cellular complexity arose through long-term microbial alliances rather than a single evolutionary event. @nature.com ➡️ shorturl.at/kCij7 📌 DOI: 10.1038/s41586-026-10639-9
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IRB Barcelona @irbbarcelona.org · 08/05/2026
✨ Join us at #IRBBarcelona Open Day! 📅 Saturday, May 30 A day of science, discovery, and hands-on activities for all ages. 🎟️ Sign up and don’t miss it! 👉 bit.ly/4ddD7VA #ExperimentaIRB
youtu.be
Vine a la Jornada de Portes Obertes de l'IRB Barcelona!
L’any passat va ser brutal... 😍🔬 Vam descobrir plegats com la ciència pot transformar el món.🔁 I aquest any repetim. Jornada de Portes Obertes de l'@IRBBa...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 28/05/2026
De camino a Bilbao donde partiparé en #SEIMC2026 con una ponencia sobre virulencia, resistencia, y adaptación en hongos patógenos. www.seimc2026.org
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Javier Santoyo @jsantoyo.bsky.social · 02/12/2025
MeTAline: enabling reproducible and scalable metagenomic analyses. #MetagenomicAnalysis #ShotgunMetagenomics #Snakemake #Containers #HPC #Bioinformatics #Genomics #NARgenomicsAndBioinformatics 🧪🧬 🖥️ academic.oup.com/nargab/artic...
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 21/05/2026
Once more our group was present in the nice FEBS advanced course #hfp2026 at La Colle. With presentations and posters by @tonigabaldon.bsky.social Mrina, and Vlad. As always the conference was great! Thank you to the organizers!
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 15/05/2026
#post Read our "behind the paper" blog post on our latest publication on #Asgard phylogenomics to get a starter on the significance of our findings. by @microbiobits.bsky.social and @tonigabaldon.bsky.social Enjoy 👇 communities.springernature.com/posts/how-th...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 13/05/2026
Was a pleasure to participate as an invited speaker at the 7th retreat of the Biology Dept of university of Padova!. This have me the chance to visit the oldest preserved botanical garden.
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 08/05/2026
#paper Echinocandin-resistant Nakaseomyces glabratus can retain fitness across host niches. This could help explain breakthrough infections. FKS requirements are niche-specific: FKS1/FKS2 support gut colonization, while FKS2 is key for systemic infection. journals.asm.org/doi/10.1128/...
journals.asm.org
Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during in...
The increasing rate of drug-resistant microbes stands as one of the major public health threats facing modern medicine (1). The severity of the emerging threat of drug resistance is more profound for ...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 12/04/2026
#Paper Our new study on #Asgard archaea is out in Nature Communications. We find a distinctive evolutionary pattern: widespread #HGT, but genome expansion mainly through gene duplication. An interesting window into the origins of #eukaryotic complexity. www.nature.com/articles/s41...
nature.com
Phylogenomics of Asgard archaea reveals a unique blend of prokaryotic-like horizontal transfer and eukaryotic-like gene duplication - Nature Communications
The genomes of Asgard archaea, the closest prokaryotic relatives to eukaryotes, are larger than those of other archaea and contain multiple genes seemingly acquired from bacteria. Here, Manzano-Morale...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 21/04/2026
#ESCMIDGlobal2026 is over. The group participated with oral presentations from Hrant Hovhannisyan (computational multiplexing optimization) and @tonigabaldon.bsky.social (evolutionary genomics of #Candida ), there was a lot of learning and networking.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 08/04/2026
Eukaryotes didn't just arise from two partners. Phylogenomics of the LECA proteome reveals multiple waves of bacterial HGT, some predating mitochondrial endosymbiosis, plus a possible role for giant viruses. www.biorxiv.org/content/10.1101/202…
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 21/04/2026
#ESCMIDGlobal2026 is over. The group participated with oral presentations from Hrant Hovhannisyan (computational multiplexing optimization) and @tonigabaldon.bsky.social (evolutionary genomics of #Candida ), there was a lot of learning and networking.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 19/04/2026
Will be at #ESCMIDGlobal2026 for the next days. Looking forward to meet colleagues and present our work on #Candida
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IRB Barcelona @irbbarcelona.org · 13/04/2026
🔬 New #FAQ drops key insights on Barcelona's #AfricanSwineFever outbreak from @gabaldonlab.bsky.social: They've sequenced the outbreak strain's genome and compared it with known variants to trace origins and characteristics. ➡️ shorturl.at/P02ME #ASF @tonigabaldon.bsky.social
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 12/04/2026
#Paper Our new study on #Asgard archaea is out in Nature Communications. We find a distinctive evolutionary pattern: widespread #HGT, but genome expansion mainly through gene duplication. An interesting window into the origins of #eukaryotic complexity. www.nature.com/articles/s41...
nature.com
Phylogenomics of Asgard archaea reveals a unique blend of prokaryotic-like horizontal transfer and eukaryotic-like gene duplication - Nature Communications
The genomes of Asgard archaea, the closest prokaryotic relatives to eukaryotes, are larger than those of other archaea and contain multiple genes seemingly acquired from bacteria. Here, Manzano-Morale...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 11/04/2026
We put together this FAQ on the African swine fever outbreak in Barcelona, based on current evidence. My group helped sequence the outbreak strain and compare it with other #ASFV virus genomes to explore its origins and features. #AfricanSwineFever www.pig333.com/articles/fre...
pig333.com
Frequently asked questions about the ASF virus detected in Barcelona
The virus detected in Barcelona is ASF genotype II and has been classified in a new genetic group: #29.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Molecular Systems Biology @molsystbiol.org · 24/03/2026
fitness costs are associated with acquired antifungal resistance in N. glabratus, and these trade-offs can be targeted by drugs as shown by @gabaldonlab.bsky.social ➡️ link.springer.com/article/10.1...
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Toni Gabaldón @tonigabaldon.bsky.social · 24/02/2026
As part of @bsc-cns.bsky.social participation at the #MWC26 and #4YN I will be presenting our applications of using hashtag#IA for the early diagnosis of colorectal cancer from fecal microbiome profiles (#MiCRC) Come and meet me on the 4th March at our booth x4hpc.cat/mwc26/agenda...
x4hpc.cat
Agenda - BSC MWC 2026 Agenda
Explore BSC's agenda for 4YFN 2026, featuring key events and presentations on cutting-edge technology and innovations. Discover what’s next at the Mobile World Congress.
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IRB Barcelona @irbbarcelona.org · 09/02/2026
For 25 years, @icreacommunity.bsky.social has strengthened Catalonia’s research ecosystem by attracting top scientific talent worldwide.  This report by @crisaez.bsky.social for @ara.cat shows why investing in top scientific talent is a decisive research strategy. ➡️ shorturl.at/SANnO
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
BSC-CNS @bsc-cns.bsky.social · 09/02/2026
🦠"Estem estudiant com els canvis que es produeixen en la microbiota intestinal s’associen al càncer colorectal. O com els bacteris de la boca estan implicats en la hipertensió". 🗞 Toni Gabaldon, investigador @icreacommunity.bsky.social del BSC i @irbbarcelona.org a l' @ara.cat
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
Diari ARA @ara.cat · 06/02/2026
Són poc més de les 6.30 del matí. La paleoantropòloga nord-americana Ashley Hammond fa estona que és desperta, donant mamar al seu fill, de dos mesos. Ho té tot calculat...
ara.cat
L’extraordinària lliga que atrau els millors científics del món a Catalunya
Aquesta iniciativa de captació i retenció de talent, pionera al món i que ha inspirat altres programes internacionals, ha impulsat el sistema de recerca del nostre país
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Reposted by Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón)
IreneJulca @irenejulca.bsky.social · 02/02/2026
(1/3) I am very happy to share that I’ll be moving to Aarhus University as an Assistant Professor in March. During these years, I’ve met so many great people who supported me on this path, and even if I can’t name everyone here, I’m truly grateful to all of you!
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Toni Gabaldón @tonigabaldon.bsky.social · 23/01/2026
Congratulations to @paucarazo.bsky.social and the other organizers of the #sesbe2026 meeting of the @sesbe-org.bsky.social . It has been a wonderful conference with nice talks, posters and networking, I the wonderful city of Valencia, my home town.
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Toni Gabaldón @tonigabaldon.bsky.social · 23/01/2026
This has been my last meeting as president of @sesbe-org.bsky.social and I wish all the best for the new board, led by the excellent newly elected president @isabelalmudi.bsky.social . I am sure they will do amazing things.
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 23/01/2026
Moisès Bernabéu from the group presented our work on the origins of the Last Eukaryotic Common Ancestor at #sesbe2026. Multiple interacting partners shaped our ancestor’s genome
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 22/01/2026
Now Edu Ocaña Pallarès, previous postdoc in the group, now PI at UOC presenting the timetree of fungi, calibrated with fossils and HGT. Nice to see #fungi at the paleobiology session in #sesbe2026
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 21/01/2026
Several of us are attending #sesbe2026 in Valencia. Today Saioa Manzano @microbiobits.bsky.social presented her work on evolution of Asgard archea genomes, showing they show a blend of eukaryotic-like and prokaryotic like processes.
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Comparative genomics group IRB-BSC Barcelona (PI: Toni Gabaldón) @gabaldonlab.bsky.social · 18/01/2026
📣 #paper "Uncovering actionable trade-offs of antifungal resistance in a yeast pathogen" Check out our new publication in @molsystbiol.org where we systematically map stress-related trade-off associated with drug resistance in Candida glabrata (N. glabratus) link.springer.com/article/10.1...
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