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Eva Pillai

@evapillai.bsky.social
1.2K followers 781 following 58 posts

mechanics | multicellularity |evolution | choanoflagellates Between the Diz-Muñoz + Arendt labs (EMBL, Heidelberg) and Thibaut Brunet’s lab (Institut Pasteur). PhD: mechanics in nervous system development @FranzeLab

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Reposted by Eva Pillai
Thibaut Brunet @thibautbrunet.bsky.social · 02/09/2026
🚨 New preprint alert! 🚨 Choanoflagellates reorganize their global cytoskeletal architecture within seconds to explore confined microspaces. This is the main PhD work of the amazing @maitefreired.bsky.social www.biorxiv.org/content/10.6... A tread 🧵⬇️
biorxiv.org
Rapid repurposing of microvillar content drives a flagellate-to-amoeboid switch in the closest relative of animals
Animal cells extensively remodel their cytoskeleton during differentiation and can notably switch between two major motility modes: flagellum-based swimming and actin-based crawling. We previously sho...
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Margherita Battistara @mbattistara.bsky.social · 08/07/2026
🪲🪰 Our preprint is out! This was a team effort with @wolframponisch.bsky.social, @matthewabenton.bsky.social and Ewa Paluch. We asked whether Drosophila and Tribolium use the same cell behaviours to fold their embryos during gastrulation. 🧵👇 www.biorxiv.org/content/10.6...
biorxiv.org
Morphospace analysis reveals divergent cellular behaviours driving tissue internalisation during insect gastrulation
During gastrulation, embryonic epithelia undergo large-scale remodelling to internalise the mesoderm. Whether the cellular mechanisms underlying these tissue deformations are conserved across species ...
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Buzz Baum @buzzbaum.bsky.social · 26/06/2026
Archaeaophiles! Last chance to sign up as a virtual attendee for MBoA2026. It’s cheap and you will have access to all the talks include our archaea@50 celebration with a special guest: meetings.embo.org/event/26-arc...
meetings.embo.org
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
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Aissam Ikmi @aikmi.bsky.social · 20/03/2026
Our study on shape diversity in cnidarians is now published. The final version includes extensive new data that substantially extend the original bioRxiv preprint. Congrats to everyone who contributed to this work! www.cell.com/cell/fulltex... @embl.org
cell.com
Deciphering mechanical determinants of morphological evolution
A comparative analysis of cnidarian larval morphogenesis combined with active surface theory identifies a set of mesoscale mechanical modules that predict species-specific shapes. Manipulating these m...
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Eva Pillai @evapillai.bsky.social · 21/03/2026
Congratulations Agathe!
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Noa Ottilie Borst @ottilie.bsky.social · 18/03/2026
Excited to share my first preprint from my PhD w/ @justinmcrocker.bsky.social. We show that cell type-specific regulatory dominance promotes robustness and evolutionary innovation through interallelic transcriptional hubs, potentially expanding the mutational paths available to diploids. (1/18)
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Buzz Baum @buzzbaum.bsky.social · 12/03/2026
Archaea hit prime time: www.bbc.co.uk/programmes/m...
bbc.co.uk
BBC Radio 4 - In Our Time, Archaea
How a discovery in the 1970s changed the theory of the origin of complex life on earth.
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Gautam Dey @gautamdey.bsky.social · 04/02/2026
Thank you @mollyherring.bsky.social for the stunning showcase 😍 Like what you see? Come ExM with us! Let’s flood the internet with microbial marvels 🦠 #ProtistsOnSky #MicroEvoSky 🧪🔬🌍 @dudinlab.bsky.social @centriolelab.bsky.social @moorefound.bsky.social @embl.org @erc.europa.eu @embo.org
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Eva Pillai @evapillai.bsky.social · 04/02/2026
Thank you Adrien!! Super chuffed to have this out 🥳🥳
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Eva Pillai @evapillai.bsky.social · 04/02/2026
Thank you Adrien!!
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Eva Pillai @evapillai.bsky.social · 25/01/2026
#LivingArchitectures Brought further to life by the stunning music of Alexandre Desplat, Philippe Hersant, and Kaija Saariaho
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Eva Pillai @evapillai.bsky.social · 25/01/2026
#LivingArchitectures is a glorious convergence of science and art. @manuelthery.bsky.social and the #CytoMorphoLab turn the Orsay into a living canvas - its walls and ceilings pulsating with life. Cytoskeletal asters bloom. Cells stream, pause and surge. Magnifique!
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Eva Pillai @evapillai.bsky.social · 22/01/2026
Congratulations Rashmi!!! ❤️❤️❤️🐟🐟🐟🍾🍾🍾
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Eva Pillai @evapillai.bsky.social · 20/01/2026
Thank you Wayo!!! Hope all is well on your end
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Eva Pillai @evapillai.bsky.social · 20/01/2026
Thank you all for the herculean experimental efforts, insightful discussions, and shared curiosity that drove this project forward!
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Eva Pillai @evapillai.bsky.social · 20/01/2026
Such an incredible group of people I had the privilege to work with on this project @sudimukherjee.bsky.social @franzelab.bsky.social, @niklasgampl.bsky.social, Ross McGinn, Katrin Mooslehner, Julia Becker, @alexwinkel.bsky.social, Amelia Thompson and all the other wonderful Franze lab folk
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Eva Pillai @evapillai.bsky.social · 20/01/2026
Thank you Benita!! ❤️❤️❤️
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Eva Pillai @evapillai.bsky.social · 19/01/2026
🐸🐸🐸 I’m going to miss doing science with you now that this is out 🥲 We must find other things to do together!
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Eva Pillai @evapillai.bsky.social · 19/01/2026
Thank you Elias!!
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Eva Pillai @evapillai.bsky.social · 19/01/2026
Thank you Christophe!!
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Eva Pillai @evapillai.bsky.social · 19/01/2026
Thank you Juan!!! So glad to have this study out!
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Eva Pillai @evapillai.bsky.social · 19/01/2026
🥳🥳🥳 Pretty fab start to 2026!!
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Eva Pillai @evapillai.bsky.social · 08/01/2026
Bon année Alex!
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Eva Pillai @evapillai.bsky.social · 06/01/2026
Lucky year?! #galettedesrois
A wedge of galette des Rois (a French pastry containing almond frangipane) with the ceramic lucky charm While galette des Rois (a French pastry containing almond frangipane) with a wedge cut out
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Eva Pillai @evapillai.bsky.social · 25/12/2025
Seasons greetings!
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Eva Pillai @evapillai.bsky.social · 17/12/2025
Congratulations Omaya! 🍾
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Maik Bischoff @maikbischoff.bsky.social · 27/11/2025
So excited to share this as a new junior PI: My brand-new lab website! 🎉🪰🌀 www.bischofflab.com Please pass it on to young, motivated researchers looking for PhD positions 😊 And for the #FluorescenceFriday community: don’t miss the SciArt Gallery! #CellBio #DevBio #PhDjob #PhDposition #Science
The brand new website of the Bischoff lab... together with my SciArt Gallery :)
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Jana Helsen @helsenjana.bsky.social · 26/11/2025
How do new centromeres evolve while staying compatible with the division machinery? Discover it in our new Nature paper! We show centromeres transition gradually via a mix of drift, selection, and sex, reaching new states that still work with the kinetochore. 👉 doi.org/10.1038/s41586-025-09779-1
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Eva Pillai @evapillai.bsky.social · 26/11/2025
Congratulations Romain!! 🪰💥
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EMBL DB unit @embldbunit.bsky.social · 20/11/2025
In this week's DB unit seminar @embl.org, Eva Pillai @evapillai.bsky.social , a postdoc in the Arendt, Diz-Muñoz @diz-lab.bsky.social and Brunet groups @thibautbrunet.bsky.social , shared insights on the role of cell surface mechanics in multicellularity, using choanoflagellates as a model organism
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🧬Jacob L Steenwyk @jlsteenwyk.bsky.social · 13/11/2025
NEW pub in @science.org 🥳 Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life? For over 15 years, #phylogenomic studies have been divided. We provide new evidence suggesting that... 🔗: www.science.org/doi/10.1126/...
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Tanmay Bharat @tbharat-lab.bsky.social · 07/11/2025
An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...
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Florian Wollweber @florianwollweber.bsky.social · 21/03/2025
Asgard archaea are full of surprises, this time we found (tiny) microtubules (snapshots of microtubule evolution?!) - Check out our new paper on the cytoskeleton of Lokiarchaeum ossiferum: www.cell.com/cell/fulltex...
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Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · 31/10/2025
🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...
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Flora Vincent @floravincent.bsky.social · 31/10/2025
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n #ProtistsOnSky tinyurl.com/2zxaund7
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Eva Pillai @evapillai.bsky.social · 31/10/2025
Glorious images and beautiful science! Congratulations to all, and what a hallowed date to get a paper out ;)
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Eva Pillai @evapillai.bsky.social · 29/10/2025
Beautiful autumn morning @embl.org Heidelberg
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Pawel Burkhardt @pawelburkhardt.bsky.social · 27/10/2025
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience Our latest in @natrevneuro.nature.com Link: rdcu.be/eMX3E @jeffcolgren.bsky.social @msarscentre.bsky.social
rdcu.be
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
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Eva Pillai @evapillai.bsky.social · 25/10/2025
Wow!! That is spectacular!!
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Thibaut Brunet @thibautbrunet.bsky.social · 05/10/2025
Latest from ours: www.cell.com/cell-reports... This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
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Eva Pillai @evapillai.bsky.social · 08/10/2025
Deeply saddened by Sir John Gurdon’s passing. A pioneer in developmental biology and Nobel laureate with endless curiosity and humility (I’ll never forget the day he asked me -then a student- to teach him a protocol in the institute bearing his name!). Elegant science, fabulous hair… truly a legend!
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Aafke Gros @aafkegros.bsky.social · 24/09/2025
Automatic filament tracing in 3D data is now only a few clicks (or one macro) away! In the amazing #BigTrace FIJI plugin by @ekatrukha.bsky.social 🤩 My workflow will be to autotrace and then manually correct the autotraces, reducing the time for our tracing significantly!
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Eva Pillai @evapillai.bsky.social · 11/09/2025
🤯🤩
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Thibaut Brunet @thibautbrunet.bsky.social · 09/09/2025
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
cell.com
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...
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Idoia Quintana-Urzainqui @idoiaeu.bsky.social · 02/09/2025
🧠🦈Excited to present our latest work🧠🦈Interested in brain evolution? And shark embryos? Then read on… Our work sheds light on the deep origins of our brain’s most complex regions.
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Eva Pillai @evapillai.bsky.social · 07/09/2025
Congratulations Bruno!!! This is some beautiful science 🤩
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Thibaut Brunet @thibautbrunet.bsky.social · 04/09/2025
Beautiful story that combined mechanobiology, evolution, and the power of fly (opto)genetics to make sense of the cephalic furrow. It was a pleasure writing the News & Views. No doubt this is still just the beginning for the field of mechano-evo-devo! Hats off to all involved
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Nature @nature.com · 27/08/2025
For some three billion years, unicellular organisms ruled Earth. Then, around one billion years ago, a new chapter of life began go.nature.com/3JyRV4S
go.nature.com
How did life get multicellular? Five simple organisms could have the answer
Single-celled species that often stick together in colonies have researchers rethinking the origin of animals.
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Gautam Dey @gautamdey.bsky.social · 07/08/2025
Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social
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Toby Andrews @tobyandrews.bsky.social · 06/08/2025
Thrilled to bits to see our latest work online in Dev Cell! 🥳 We wanted to know how cells build functional organs with precision🫀🫁📏 Here we show how coupling of cell shape and organ function fine tunes the form and contractile power of the developing #zebrafish heart 1/n tinyurl.com/cell-stretch
tinyurl.com
Mechanochemical coupling of cell shape and organ function optimizes heart size and contractile efficiency in zebrafish
Andrews et al. demonstrate that multiscale feedback between mechanical and chemical cues builds a functional heart to support zebrafish embryonic life. Cell recruitment and organ-scale forces drive tr...
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