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Michael Epstein

@epsteinstatgen.bsky.social
242 followers 213 following 34 posts

Faculty at Emory Human Genetics, periodically cool dad, typical Boston sports fan (sorry), big believer in Dunning-Kruger effect

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Michael Epstein @epsteinstatgen.bsky.social · 05/06/2026
For those interested in studying cell-cell communication, check out our latest methodological work in AJHG where we discuss more powerful and practical techniques for this task. Project was joint effort with @yjingj.bsky.social and led by our incredible trainee Dr. Qile Dai (now at Lilly)
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The American Journal of Human Genetics @ajhgnews.bsky.social · 04/06/2026
🧬Online now! 📄Identifying condition-related cell-cell communication events using supervised tensor analysis 🧑‍🤝‍🧑 @epsteinstatgen.bsky.social @yjingj.bsky.social & Dai 🖥️ github.com/daiqile96/ST...
cell.com
Identifying condition-related cell-cell communication events using supervised tensor analysis
Cell-cell communication (CCC) events coordinate physiological functions in multicellular organisms and are important for exploring biological processes and disease mechanisms. We introduce STACCato, a...
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Andrew Bass @ajbass.bsky.social · 25/11/2025
Happy to see this out w/ @epsteinstatgen.bsky.social and @davecutler.bsky.social (paper: doi.org/10.1093/bioi...)! We tackled the problem of identifying dysregulated pathways (i.e. differentially co-expressed) in gene expression studies. We show that differential co-expression arises ...
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Haky Im @hakyim.bsky.social · 12/09/2025
I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.
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Andrew Bass @ajbass.bsky.social · 25/08/2025
Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs. Paper: www.nature.com/articles/s43...
nature.com
Exploiting pleiotropy to enhance variant discovery with functional false discovery rates - Nature Computational Science
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...
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Michael Epstein @epsteinstatgen.bsky.social · 22/07/2025
RIP, Prince of Darkness. Arguably in the Top 5 of most influential artists of my lifetime
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Michael Epstein @epsteinstatgen.bsky.social · 23/06/2025
Our new AJHG paper is online. We develop a new TWAS tool that uses local-ancestry information to improve power of gene mapping in admixed samples. Lead author Taylor Head (now at MD Anderson) did a phenomenal job spearheading this work!
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Sasha Gusev @sashagusevposts.bsky.social · 19/04/2025
Incredible GRC Genetics and Genomics conference line-up this year in Portland, Maine (www.grc.org/human-geneti...). With conference-maxxing sessions that run to 9:30pm! Submission deadline is June 8th, conference July 6-11th.
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Bjarni Vilhjalmsson @bvilhjal.bsky.social · 25/03/2025
Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15) Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark! #Postdoc #Epidemiology #StatisticalGenetics #Biostatistics 👉 international.au.dk/about/profil...
international.au.dk
Postdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus University
Vacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University
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Julia Métraux @juliametraux.bsky.social · 25/12/2024
Happy Chrismukkah to all the delightful half-half situations (like me)
Stills from the show Schitt's Creek in a shop. One character, a white man asks, "Do I not get a Merry Christmas?" A woman, who is also white, responds, "I thought you were Jewish." He responds back, "I'm a delightful half-half situation."
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Austin Kocher, PhD @austinkocher.com · 15/12/2024
Accurate.
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Michael Epstein @epsteinstatgen.bsky.social · 04/12/2024
For those working in pathway and co-expression analysis, check out Andy’s recent preprint describing a more powerful and flexible framework for such studies!
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MattBloodMD @doctorblood.bsky.social · 29/11/2024
We humbly thank the reviewers for their suggestions. We would like to resubmit this improved manuscript for your consideration. #AcademicSky #MedSky
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Josh Weinstock @joshweinstock.bsky.social · 22/11/2024
I'm developing a pipeline to call CHIP mutations in UK Biobank using the DNA Nexus RAP that is fast/cheap/reproducible. Initial results are promising; calls looks reasonable and cost to do this across all of UKB is likely < 500$. Feel free to DM if of interest.
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Matthew L Reznicek @drreznicek.bsky.social · 06/08/2024
Finally a VP who’s had to design a syllabus!
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Michael Epstein @epsteinstatgen.bsky.social · 01/05/2024
Excited to share our method LIT; a kernel approach to map genetic variants with interaction effects on multiple phenotypes in biobanks. R package implementing the method available on CRAN. Kudos to Andy Bass for leading this work! genomemedicine.biomedcentral.com/articles/10....
genomemedicine.biomedcentral.com
Identifying latent genetic interactions in genome-wide association studies using multiple traits - Genome Medicine
The "missing" heritability of complex traits may be partly explained by genetic variants interacting with other genes or environments that are difficult to specify, observe, and detect. We propose a n...
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Josephine beckbook.com Riesman @josie.zone · 14/11/2023
CHARLIE BROWN: Can I kick it? LUCY: Yes, you can! CHARLIE BROWN: Can I *kick* it? LUCY: Yes, you can! CHARLIE BROWN: Can I _kick_ it. LUCY: Yes, you can! CHARLIE BROWN: {running toward ball} Well, I’m gone! LUCY: {pulling the ball away} Gone!
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MadScientist @mads100tist.bsky.social · 31/10/2023
Please be sure to check you kid's candy this year. I just found another project I have no time for in a Reese's cup
A Reese's butter cup with scientific papers, images and data coming out of it
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Haky Im @hakyim.bsky.social · 21/10/2023
Preprint is up now www.biorxiv.org/content/10.1...
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Linda Kachuri @lindakachuri.bsky.social · 16/10/2023
Trying to be better with sharing work on here 😅 Check out our paper that identifies novel immune-mediated risk factors for glioma. We also found interesting genetic associations with survival and features of the tumor immune microenvironment 🧬 🧠
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Nicholas Mancuso @nmancuso.bsky.social · 03/10/2023
👋 Hi genetics/statgen/gen-epi trainees! 🧬 🧪 If you are interested in reviewing please let me know! We (HGG Advances, eLife) are constantly in need of knowledgeable reviewers and would be more than happy to work with you. Please feel free to email me (or other editors) if you're interested!
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Michael Epstein @epsteinstatgen.bsky.social · 01/10/2023
Pep and jazz band member Latin Club member who also took Ancient Greek Listened to Rush 24/7. I checked all the boxes
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Richard Sever @richardsever.bsky.social · 28/09/2023
bioRxiv goes big on Bluesky: accounts for all subject categories now available (Please Reskeet) connect.biorxiv.org/news/2023/09...
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Michael Epstein @epsteinstatgen.bsky.social · 15/09/2023
Introducing some cool work by @ajbass.bsky.social in my lab for detecting genetic variants with interactive effects on phenotypes of interest in biobanks leveraging pleiotropy. Hope you find it interesting!
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Michael Epstein @epsteinstatgen.bsky.social · 12/09/2023
Just curious; what is the longest wait time anyone has experienced for a desk rejection?
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Veera Rajagopal @doctorveera.bsky.social · 09/09/2023
GWAS of antimullerian hormone (AMH) levels in the Finnish population. One of the hits is CHEK2 driven by a loss of function variant that is 4x enriched in Finland. Pujol-Gualdo et al. medRxiv www.medrxiv.org/content/10.1...
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Michael Epstein @epsteinstatgen.bsky.social · 28/08/2023
My latest cure for writer’s block
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Michael Epstein @epsteinstatgen.bsky.social · 10/08/2023
@danirabaiotti.bsky.social : could I please be added to the science feed? Thanks so much!
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Gillian Branstetter @gbbranstetter.bsky.social · 02/08/2023
What cheat codes unlock the secret character
A CNN screenshot featuring six co-conspirators featured n the Trump election fraud indictment
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Michael Epstein @epsteinstatgen.bsky.social · 01/08/2023
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Carl T. Bergstrom @carlbergstrom.com · 28/07/2023
Via Mark Reid on Mastodon, a major breakthrough in Computer Science. mastodon.social/@mdreid/11078859037…
The fedex exploit: a post at ICML.
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Michael Epstein @epsteinstatgen.bsky.social · 27/07/2023
Hi! I have a PhD in Biostatistics and work on developing/applying statistical tools to improve understanding of genetic basis of various complex traits (current focus: Alzheimer’s disease and breast cancer). Thx to marine conservationist (and brainy cousin) @katieocean.bsky.social for the invite!
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