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Andrew Bass

@ajbass.bsky.social
52 followers 74 following 9 posts

Post-doc Wallace lab, PhD Storey lab

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Andrew Bass @ajbass.bsky.social · 25/11/2025
Happy to see this out w/ @epsteinstatgen.bsky.social and @davecutler.bsky.social (paper: doi.org/10.1093/bioi...)! We tackled the problem of identifying dysregulated pathways (i.e. differentially co-expressed) in gene expression studies. We show that differential co-expression arises ...
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Andrew Bass @ajbass.bsky.social · 25/08/2025
Excited to see our (w/ @chr1sw.bsky.social) work published in @natcomputsci.nature.com! We developed a new framework, surrogate functional false discovery rate (sffdr), that integrates summary statistics of related traits to improve power in GWASs. Paper: www.nature.com/articles/s43...
nature.com
Exploiting pleiotropy to enhance variant discovery with functional false discovery rates - Nature Computational Science
This study introduces a cost-effective strategy called surrogate functional false discovery rates to increase power in genome-wide association studies by leveraging genetic correlations (or pleiotropy...
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Andrew Bass @ajbass.bsky.social · 04/12/2024
Differential co-expression arises from shared unmodeled biological variation involving an observed risk factor and an unobserved (or latent) factor. We developed a method to detect such variation in a pathway for general gene expression studies!
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Andrew Bass @ajbass.bsky.social · 28/09/2024
New work with @chr1sw.bsky.social on increasing GWAS power by leveraging summary statistics of related traits! Package available at github.com/ajbass/sffdr.
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Reposted by Andrew Bass
Emory Department of Human Genetics @emorygenetics.bsky.social · 02/05/2024
New publication from @epsteinstatgen.bsky.social's crew describing LIT; a kernel method to map genetic variants with interaction effects on multiple phenotypes in biobanks - in Genome Medicine genomemedicine.biomedcentral.com/articles/10....
genomemedicine.biomedcentral.com
Identifying latent genetic interactions in genome-wide association studies using multiple traits - Genome Medicine
The "missing" heritability of complex traits may be partly explained by genetic variants interacting with other genes or environments that are difficult to specify, observe, and detect. We propose a n...
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Andrew Bass @ajbass.bsky.social · 13/09/2023
A preprint of my first post-doc paper w/ Shijia Bian, Aliza Wingo, Thomas Wingo, David Cutler and @epsteinstatgen.bsky.social is out! www.biorxiv.org/content/10.1...
biorxiv.org
Identifying latent genetic interactions in genome-wide association studies using multiple traits
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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