Reposted by Bjarni VilhjalmssonBehavEcolPapers @behavecolpapers.bsky.social · 17/03/2026Mapping the heritability of disease: a nationwide study @natcomms.nature.comdlvr.itMapping the heritability of disease: a nationwide studyNature Communications, Published online: 17 March 2026; doi:10.1038/s41467-026-69991-zUnderstanding genetic and environmental contributions requires large‑scale heritability data. Here, the authors analyse more than 10 million Danish health records, estimating heritability for 1,000+ diseases and revealing trait‑specific differences between family‑based and SNP‑based estimates. 042
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 28/10/2025Great work by the amazing Fenfen Ge on how suicide attempts and suicides have surprisingly different risk factors. 050
Reposted by Bjarni VilhjalmssonGerome Breen @psychgenomics.bsky.social · 26/05/2025Group poster today from @jaredgm.bsky.social on genetics of perinatal depression. Jared is a DepGenAfrica postdoc - he is looking for collaborators with African PND data also. Visit poster P018.085D today at 4pm! #eshg2025 054
Reposted by Bjarni VilhjalmssonMarios Georgakis @mariosgeorgakis.bsky.social · 24/04/2025Massive multi-ancestry GWAS resource for 1,167 clinical traits & diseases in 6 global biobanks (n=1,789,365) 👉29,139 locus-trait pairs 👉2,624 non-overlapping loci across the genome 👉associated with 6 traits each (median) 👉colocalization across traits for 72% of loci [1/3] 1167
Reposted by Bjarni VilhjalmssonJordi Merino @jmerino.bsky.social · 24/04/2025What does it take to launch a precision health study? A bold vision, an exceptional team, a supportive ecosystem, and perseverance! We are proud to introduce the Danish Precision Health Initiative: a resource built to drive precision cardiometabolic health research for years to come. delphi.ku.dkdelphi.ku.dkDELPHI 192
Reposted by Bjarni VilhjalmssonSMARTbiomed @smartbiomed.bsky.social · 02/04/2025📢 Applications open for the SMARTbiomed Summer School! 🧠 Learn Causal Inference, Statistical Genetics & ML in R 📍 June 23–27 at the stunning Sandbjerg Estate, Denmark ⏳ Apply by April 19 — limited spots available! 👩🔬 For PhDs, postdocs & early-career researchers 🔗 smartbiomed.dk/news-and-eve...smartbiomed.dk 176
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 25/03/2025Multiple Postdoc Positions available in Epidemiology, Biostatistics, or Statistical Genetics (deadline April 15) Join an International team at the Pioneer Centre for SMARTbiomed, Aarhus, Denmark! #Postdoc #Epidemiology #StatisticalGenetics #Biostatistics 👉 international.au.dk/about/profil...international.au.dkPostdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus UniversityVacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University 1198
Reposted by Bjarni VilhjalmssonMicah G. Allen @micahgallen.com · 18/03/2025I’m always happy to discuss the pros and cons of academic/neuroscience life in Denmark. Like any small European country there are some hurdles but it is overall an excellent place to be. We’re happy here. 3587
Reposted by Bjarni VilhjalmssonSMARTbiomed @smartbiomed.bsky.social · 12/03/2025We are seeking talented researchers for multiple postdoctoral positions in Epidemiology, Biostatistics, or Statistical Genetics at the Pioneer Centre for SMARTbiomed at Aarhus University, Denmark. international.au.dk/about/profil...international.au.dkPostdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus UniversityVacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University 032
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 11/03/2025We're hiring Pioneer Fellow Postdocs!! Join us at the Pioneer Centre for SMARTbiomed to develop innovative methods in epidemiology, biostatistics, and statistical genetics, working with big biomedical data. international.au.dk/about/profil... #StatGen #Epi #Postdoc #SMARTbiomedinternational.au.dkPostdocs in Epidemiology or Statistical Genetics at The Pioneer Centre for SMARTbiomed - Vacancy at Aarhus UniversityVacancy at Department of Public Health - NCRR - National Centre for Register-based Research, Aarhus University 12112
Reposted by Bjarni VilhjalmssonAnthony Herzig @anthony-herzig.bsky.social · 02/02/2025EMGM2025 abstract deadline extended – 09/02 (final). Conference 8-9 April, Brest, France. Everything statistical and population genetics, genetic epidemiology, bioinformatics… Invited speakers: Céline Bon, Beatriz Cuyabano, Garrett Hellenthal. emgm2025.sciencesconf.orgemgm2025.sciencesconf.org53rd European Mathematical Genetics Meeting - Sciencesconf.org 133
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 24/01/2025ESHG Abstract Deadline Reminder! The Submission Deadline for #ESHG2025 is in a week (Jan 30)! Please join us this spring (May 24-27) in Milan, Italy, for another fun and exciting ESHG conference! Learn more at 2025.eshg.org Please retweet. #Genetics #ScienceConference #ESHG #ESHG2025 063
Reposted by Bjarni VilhjalmssonJoyce Kao @joyceykao.bsky.social · 11/12/2024Would you like to chat about all things #OpenScience in the Swiss Alps? 😆🇨🇭 033
Reposted by Bjarni VilhjalmssonStinus Lindgreen @stinuslindgreen.bsky.social · 18/01/2025Den store Danmarks Indsamling starter i dag. Jaja, man kan byde på frokost, rundvisning osv. med folketingsmedlemmer - men man kan også opleve det aarhusianske dødsmetalband Livløs sammen med folketingets eneste heavy metal-ordfører 🤘 Tak til bandet for støtten #dkpol www.lauritz.com/da/auction/k...lauritz.comLauritz.com - Online AuktionerKøb og sælg kunst, design, antikviteter og meget mere. 1456
Reposted by Bjarni VilhjalmssonStinus Lindgreen @stinuslindgreen.bsky.social · 16/01/2025Kort før jul lavede regeringen sammen med SF, LA, Danmarksdemokraterne og Konservative nogle småjusteringer af den dumme, dyre og dybt skadelige kandidatreform. Det er dog som et plaster på et åbent benbrud. Det skriver jeg om i @Altingetdk #dkpol www.altinget.dk/forskning/ar...altinget.dkDe politiske småjusteringer løser ikke kandidatreformens kerneproblemerPå trods af de politiske småjusteringer af kandidatreformen, kommer den fortsat til at gøre stor skade i uddannelses- og forskningsmiljøer, skriver Stinus Lindgreen. 05311
Reposted by Bjarni VilhjalmssonSMARTbiomed @smartbiomed.bsky.social · 14/01/2025Looking for a PhD position in statistical methods development for causality? Then we might be looking for you! jobportal.ku.dk/alle-opslag/...jobportal.ku.dkPhD fellowships in Biostatistics and Causal inference at the SMARTbiomed Pioneer centre 014
Reposted by Bjarni VilhjalmssonSMARTbiomed @smartbiomed.bsky.social · 14/01/2025The Pioneer Centre for SMARTbiomed will leverage large-scale, multimodal biomedical data combined with focused innovation in statistical and computational methods including machine learning to advance our understanding, treatment, and prevention of human disease. Learn more about us: smartbiomed.dksmartbiomed.dkThe Pioneer Centre for SMARTbiomedThe Pioneer Centre is anchored at Aarhus University and will be a collaboration of researchers from Aarhus University, University of Copenhagen, and University of Oxford. 064
Reposted by Bjarni VilhjalmssonEric Topol @erictopol.bsky.social · 04/01/2025The scientist who is responsible for driving GLP-1 drugs for the treatment of obesity and testing them for prevention of Alzheimer's disease—Lotte Bjerre Knudsen— tells her story in a remarkable conversation. Full transcript, or video, all free, no ads. erictopol.substack.com/p/lotte-bjer...erictopol.substack.comLotte Bjerre Knudsen: The Scientist Who Drove GLP-1 Drugs For Obesity and Alzheimer'sFacts, data, and analytics about biomedical matters. 21652194
Reposted by Bjarni VilhjalmssonAndrea Ganna @andganna.bsky.social · 11/12/2024Interesting work! By mapping many medical ontologies to the same embedding space we can go beyond the need of time-consuming data mapping and harmonization. www.medrxiv.org/content/10.1...medrxiv.orgUnified Clinical Vocabulary Embeddings for Advancing Precision MedicineIntegrating clinical knowledge into AI remains challenging despite numerous medical guidelines and vocabularies. Medical codes, central to healthcare systems, often reflect operational patterns shaped... 0213
Reposted by Bjarni VilhjalmssonFinnGen @finngen.bsky.social · 05/12/2024Million Veteran Program & FinnGen teams are pleased to release v1 meta-analysis of MVP, FinnGen and UKBB GWAS data. This first version includes ~300 binary disease definitions across >1.5 M individuals. Browse scans at: mvp-ukbb.finngen.fi 14724
Reposted by Bjarni VilhjalmssonOleguer Plana-Ripoll @planaripoll.bsky.social · 27/11/2024📢 New publication from our group: a comprehensive study on mental health disorder trends in Denmark according to age, calendar period, and birth cohort We are excited to announce the publication of our latest research in JAMA Psychiatry: jamanetwork.com/journals/jam... More details below. 2256
Reposted by Bjarni VilhjalmssonMicah G. Allen @micahgallen.com · 02/12/2024Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know! 9385196
Reposted by Bjarni VilhjalmssonShai Carmi @shaicarmi.bsky.social · 02/12/2024There are now 50 papers (that I am now aware of) with methods for transferring polygenic scores across populations. You can find them here: drive.google.com/drive/folder... 1204
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 02/12/2024Check out our (Emil Pedersen, Theresa Wimberley, and me) news and views out today in Nature Genetics, highlighting the importance of selection bias and information bias in genetic studies. #statgen #genepi #selectionbias eur01.safelinks.protection.outlook.com?url=https%3A...eur01.safelinks.protection.outlook.comA cautionary tale for Alzheimer’s disease GWAS by proxy - Nature GeneticsUsing reported parental disease history to decipher the genetics of Alzheimer’s disease may be promising, but this approach is also susceptible to complex selection and information bias that can misle... 1358
Reposted by Bjarni VilhjalmssonMichel Nivard @michelnivard.bsky.social · 28/11/2024🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.github.comGitHub - MichelNivard/awesome-complex-trait-genetics: A list of awesome tools for complex trait genetics.A list of awesome tools for complex trait genetics. - MichelNivard/awesome-complex-trait-genetics 78243
Reposted by Bjarni VilhjalmssonDanmarks Grundforskningsfond @dg.dk · 26/11/2024We are thrilled to announce that Professor Niels Mejlgaard will assume the role of CEO of the DNRF on January 13, 2025. Learn more: dg.dk/en/new-ceo-o... 0194
Reposted by Bjarni VilhjalmssonShai Carmi @shaicarmi.bsky.social · 24/11/2024Very interesting work by Tade Souaiaia et al on the non-polygenic architecture of the extremes of complex traits. For many traits, polygenic scores show "regression to the mean" around the tails, as extreme traits are mostly due to rare alleles. www.biorxiv.org/content/10.1... 14316
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 22/11/2024The Amazing Florian Privé has joined Bluesky. He’s the author of several great R packages in #statgen, including bigsnpr and bigstatsr. 😀 040
Reposted by Bjarni VilhjalmssonAndrea Ganna @andganna.bsky.social · 20/11/2024www.nature.com/articles/s41...nature.comExamining the role of common variants in rare neurodevelopmental conditions - NaturePatients with neurodevelopmental conditions without a monogenic diagnosis have a higher polygenic burden than those with a monogenic diagnosis. Non-transmitted common all... 081
Reposted by Bjarni VilhjalmssonAlex Hoischen @ahoischen.bsky.social · 18/11/2024The preliminary #eshg25 program is online. Stellar line-up of invited speakers - full breadth of our amazing field. Grateful to a wonderful SPC @eshg that made this possible. See you all in Milan next year! 2025.eshg.org/programme-at...2025.eshg.orgProgramme at a GlancePre-conference courses Thursday, May 22, 2025 & Friday, May 23, 2025 - TBA Conference programme Saturday, May 24, 2025 08:30 - 10:00 Educational Sessions E01 E01 Single cell genomics and diseases W... 12111
Reposted by Bjarni VilhjalmssonSasha Gusev @sashagusevposts.bsky.social · 16/11/2024I wrote about Eric Turkheimer's recent book on "the nature-nurture debate", which should be of interest to people thinking not just about the genetics of behavior but complex traits more broadly. A 🧵:open.substack.comBook Review: Eric Turkheimer's "Understanding the Nature-Nurture Debate"Or, some thoughts on The Gloomy Prospect and the Gloomy Present 514352
Reposted by Bjarni VilhjalmssonAndrea Ganna @andganna.bsky.social · 20/09/2024The European Health Data Space (EHDS) act represents a incredible opportunity for health data science In a Nature Medicine commentary we discuss the present and future of EHDS This is the result of a workshop with some incredible researchers across EU countries and disciplines rdcu.be/dTKUjrdcu.beThe European Health Data Space can be a boost for research beyond bordersNature Medicine - The European Health Data Space provides an opportunity to benefit patients and the public. 095
Reposted by Bjarni VilhjalmssonBjarke Feenstra @bfeenstra.bsky.social · 03/07/2024Amazing methods-oriented PIONEER center of Biomedicine launching in DK and UK, led by Naomi Wray, @ceclindgren.bsky.social @bvilhjal.bsky.social Preben Bo Mortensen, Erin Gabriel, Chris Holmes, Peter Visscher 031
Reposted by Bjarni VilhjalmssonMike Inouye @mikeinouye.bsky.social · 24/11/2023From @bvilhjal.bsky.social and co: Inferring disease architecture and predictive ability with LDpred2-auto www.cell.com/ajhg/fulltex... 062
Reposted by Bjarni VilhjalmssonGraham Coop @gcbias.bsky.social · 17/11/2023Family-based GWAS have become the gold standard for assessing causal genetic effects. They’re often said to offer an unbiased estimate of the average causal effect (ATE) of an allele or PGS. Here, we (Carl Veller & @mollyprz.bsky.social ) evaluate such statements. www.biorxiv.org/content/10.1... 1/nbiorxiv.orgCausal interpretations of family GWAS in the presence of heterogeneous effectsbioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution 16142
Reposted by Bjarni VilhjalmssonNicky Whiffin @nickywhiffin.bsky.social · 11/10/2023Is anyone here 🧬🖥️ using the UKBiobank 200k genome dataset? We are having some weird issues and are trying to troubleshoot if data vs code. Anyone else seeing anything odd? Either way, please share (not sure what the equivalent of RT here is?) 013
Reposted by Bjarni VilhjalmssonNa Cai @caina89.bsky.social · 09/10/2023On our way to #wcpg2023! This is a big year for Cai lab, all of us have talks! 🤩 Lianyun Huang is in the UKB session, Jolien Rietkerk is in the stats methods session, and I’m in a symposium on GWAS phenotyping. I’ll remind everyone on the morning of. 😉 See you all in Montreal! 084
Reposted by Bjarni VilhjalmssonMichel Nivard @michelnivard.bsky.social · 06/10/2023This is a Bluesky feed that tracks #WCPG2023 posts for the world congres of psychiatric genetics 2023, SUBSCRIBE!: bsky.app/profile/did:... 186
Reposted by Bjarni VilhjalmssonArun Durvasula @arundurvasula.bsky.social · 24/09/2023Excited to share our latest manuscript on gene-environment interactions in the UKBiobank: www.medrxiv.org/content/10.1...medrxiv.orgDistinct explanations underlie gene-environment interactions in the UK BiobankmedRxiv - The Preprint Server for Health Sciences 22818
Bjarni Vilhjalmsson @bvilhjal.bsky.social · 23/09/2023@amirsariaslan.bsky.social tusind tak for invite 😀👍 120
