Nature Immunology - Xie et al. identify a distinct subset of CD4+ helper T cells expressing EOMES and granzyme K in both mice and human models of colitis.

Hur and colleagues review recent developments to provide insights into the molecular mechanisms and regulatory functions of the transcriptional regulators FOXP3 and AIRE.

Nitrogen is key to producing the world’s crops – but it comes at a cost. New research from CSIRO is developing future crops that produce their own fertiliser.

Type 1 diabetes was once thought to be exclusively a childhood-onset disease, but recent epidemiological evidence shows that more than half of all clinical diagnoses of type 1 diabetes occur in adulth...

Exclusive: Fixing a leak can be simple and equivalent to closing a coal power station, making lack of action maddening, say analysts

Who should pay for American science? In the current political climate, many are looking to the private sector to compensate for cuts in public funding. At the Harvard School of Public Health—particula...

This cohort study investigates associations of human milk feeding and infant gut microbes, including Bifidobacterium longum subsp infantis, with infant fecal metabolites and childhood systolic blood p...

The ability to reduce the risk of developing diabetic ketoacidosis (DKA) remains a major care gap for people with diabetes, particularly those on intensive insulin therapy. The anticipated availabilit...

Nine in 10 Australian researchers had their “ideas grant” applications rejected last year, even as Australia’s medical investment fund sits on $5 billion more than it was designed to hold.

Yifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025.

An open-source platform for data-independent acquisition proteomics adapts predicted libraries to experimental settings.

Imagine that a young woman is raped in your office. You are a minister and she is the most junior member of your staff. In the footage you see later, she is too drunk to put on her shoes. She walks ba...

A consortium of manufacturers aims to fund the sorting and processing of soft plastics for reuse – but critics say it will pass costs on to consumers * Get our breaking news email, free app or daily news podcast Almost three years after the collapse of the national soft plastics collection and recycling program REDCycle, the consumer regulator is set to greenlight an industry-led replacement scheme. But there are concerns product manufacturers and the major supermarkets will shift the program’s costs onto consumers rather than change their own behaviour of producing and stocking vast quantities of soft plastics that mostly end up in landfill. Continue reading...

In the Albanese government’s first term, Education Minister Jason Clare observed that Australia has one of the most segregated education systems in the OECD. What is deeply shocking – though not surpr...

In young people with recent-onset, clinical type 1 diabetes, 2·5 mg/kg and 0·5 mg/kg ATG reduced loss of β-cell function, showing the potential of an affordable, repurposed agent, ATG, in a low and sa...

Identifying biomarkers of functional β-cell loss is an important step in the risk stratification of type 1 diabetes. Genetic risk scores (GRS), generated by profiling an array of single nucleotide pol...

A dedicated disaster recovery force is needed, or else responders and defence forces could be "overwhelmed" by multiple concurrent natural disasters, the National Climate Risk Assessment warns.

The usual suspects are trying to whip up a scare campaign about immigration and housing. Let’s look at the numbers and put them into context.

Study says small editor group handled many problematic manuscripts — and a Nature investigation finds out who they are.

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically m...

The ancestral protein of the CRISPR–Cas9 system — less than half the size of its famous descendant — is engineered into an effective DNA-targeting tool that can be delivered by AAV as an epigenome edi...

Australian workers are feeling exhausted and burnt out and experts believe it may be time to reassess working conditions.

An investigation can reveal the secret history of one of Australia’s top scientists, whose faked data underpins a drug now being given to patients.