iiinova — where your digital self keeps evolving

Ella Hartenian @ehartenian.bsky.social · 25/06/2026

Here’s to an excellent @keystonesymposia.bsky.social conference in Hannover, Germany! A lovely location and great to see many new and familiar faces. Thanks to all for the excellent talks and stimulating discussion. #KSViral26

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Broz Lab @brozlab.bsky.social · 11/03/2026

You can hear all about this in a few weeks in Canada where @ehartenian.bsky.social will be presenting it @keystonesymposia.bsky.social on Innate Immunity

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Broz Lab @brozlab.bsky.social · 11/03/2026

We’re happy to share our updated manuscript on Ninj1, incorporating measurements of membrane tension, cellular assays of ninj1 and ninj2 dimer stability and MD simulations of ninj1 oligmers opening and forming (see below!). @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

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Ella Hartenian @ehartenian.bsky.social · 20/11/2025

Annndddd it’s out! Here’s what came out of combining my virology background with the @brozlab.bsky.social’s cell death focus : a novel role for the cell death protein ninj1 during hsv1 infection. In brief, Ninj1 on mouse macrophages results in lower infection rates and higher cytokine secretion.

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Broz Lab @brozlab.bsky.social · 11/11/2025

It’s DIB day! The annual conference for our department @dib-unil.bsky.social. Lovely day (and view!) at the Lausanne Olympic museum exchanging with our colleagues. Plus a stellar presentation on NINJ1 by our own @elliottbernard.bsky.social 🔬!

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Department of Immunobiology at UNIL @dib-unil.bsky.social · 01/10/2025

Kicking off the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors organized by our department in Lausanne! @brozlab.bsky.social @martinon.bsky.social @rebsamenlab.bsky.social @fbm-unil.bsky.social

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Ardem Patapoutian @ardemp.bskyverified.social · 22/07/2025

No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org

protectscienceandinnovation.org

Protect Science and Innovation

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Kolb Group @kolblab.bsky.social · 26/05/2025

📣Save the date! 📣 We will be hosting the 18th Mini Herpesvirus Workshop and the HHV-65 Symposium in Freiburg this year. We are very excited about all of the amazing speakers that we get to welcome. We can't wait to see you all there!

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Stand Up for Science! @standupforscience.net · 26/05/2025

🚨 URGENT RESPONSE CALL 🚨 Trump’s Fool’s Gold Science EO is a dangerous sham. It gives his appointees the power to dismiss entire bodies of research and punish researchers who fail to fall in line with his agenda. We’ve launched an open letter. SIGN & SHARE NOW: actionnetwork.org/petitions/op...

actionnetwork.org

Sign The Open Letter to Stand Up For Science Now!

Science is under siege. Trump’s latest Executive Order calls for politically appointed science commissars to evaluate research. Join us in adding your name to our open letter condemning Trump’s escala...

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eLife @elife.bsky.social · 27/03/2025

A new combination of microscopy methods has revealed exquisite details of the virus assembly process used by herpes simplex virus during replication. buff.ly/aO8W9BJ

eft: A 2D CryoSXT projection of an HSV-1 evelopment event. Right: A 3D rendering of the budding assembly stage captured by CLXT.

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Mothers in Science @mothersinsci.bsky.social · 18/03/2025

Our research shows that ~50% of mothers globally decline at least half of opportunities to participate in conferences after becoming parents (N=3995). We understand the barriers and are offering Travel Grants to help overcome these challenges. Apply now - deadline 31st March! shorturl.at/gnCU2

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Bella Rauch @rauchlab.bsky.social · 13/03/2025

Let's not forget that apart from science advocacy the Rauch lab also does kick-ass science! Together with the @psmitchej.bsky.social and Tait Wojno labs, we show that #tuftcells can induce specific protective signaling after recognition of intracellular bacterial infection via the #inflammasome!

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Indra_Beķere @indrabekere.bsky.social · 29/01/2025

I’m very excited to share our first preprint “Structural Basis for OAS2 Regulation and its Antiviral Function” from my postdoc together with Veronika Merold (Vroni) from NTase lab with @oliveiramann.bsky.social www.biorxiv.org/content/10.1...

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Stand Up for Science! @standupforscience.net · 06/03/2025

SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING! To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎

List of Stand Up for Science events—official events in red, solidarity events in blue.

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Colette Delawalla, PhD @cdelawalla.bsky.social · 09/02/2025

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.

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Silas Maniatis @manimota.bsky.social · 10/02/2025

NYGC is organizing a number of efforts to address the changes to NIH IDCs and other changes to federal policy. If you are a US citizen, or in the US working in science, please consider signing this petition. The more signatures the stronger our hand in interacting with law makers. chng.it/kK2HMP5pGk

chng.it

Sign the Petition

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

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Liz Neeley @lizneeley.bsky.social · 01/02/2025

Each week, we are collecting, reading, vetting & tagging all the links, news & rumors you’re seeing whiz past you online. We are also talking to dozens of researchers & PIs about their firsthand experiences. Every Friday, I debrief you over a drink at buttondown.com/liminalcreat...

buttondown.com

Making Sense of It All

Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...

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Ella Hartenian @ehartenian.bsky.social · 29/01/2025

The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀

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Carina de Oliveira Mann @oliveiramann.bsky.social · 29/01/2025

Happy to share the first preprint from my lab by @indrabekere.bsky.social and Veronika Merold! We solved the cryo-EM structure of the RNA immune sensor OAS2 and revealed how dimerization and subcellular localization regulate its activity! Check out Indra’s thread for a summary:

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Rebsamen Lab @UNIL @rebsamenlab.bsky.social · 28/01/2025

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky

wp.unil.ch

Symposium immunobiology

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Broz Lab @brozlab.bsky.social · 28/01/2025

Check out our latest pre print! Alexandra and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press! www.biorxiv.org/content/10.1...

biorxiv.org

Sterile- or pathogen-induced endolysosomal damage activate the NLRP6 inflammasome in human intestinal epithelial cells

NLRP6 controls host defense against bacteria and viruses in the gastrointestinal tract by a poorly understood mechanism. Here, we report that NLRP6 forms an inflammasome upon endolysosomal damage caus...

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Gregg Gonsalves @gregggonsalves.bsky.social · 04/01/2025

For those who haven't been following the cozying up to RFK Jr. by some liberals (call them what you want, they are not Republicans) and why it's dangerous. Three pieces to lay out the case. 1/

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Science News @scinews.bsky.social · 28/12/2024

The class gap in career progression: US academia First-generation college graduates are 13% less likely to end up tenured at an R1, and are on average tenured at institutions ranked 9% lower, than their PhD classmates with a parent with a (non-PhD) graduate degree. mitsloan.mit.edu/shared/ods/d...

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Science News @scinews.bsky.social · 22/12/2024

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures With models like AlphaFold3 limited to academic research, the team built an equivalent alternative, to encourage innovation more broadly www.eurekalert.org/news-release...

eurekalert.org

MIT researchers introduce Boltz-1, a fully open-source model for predicting biomolecular structures

Researchers in the MIT Jameel Clinic for Machine Learning in Health developed a fully open-source biomolecular structure prediction model that achieves state-of-the-art performance, at the level of Al...

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Science Magazine @science.org · 17/12/2024

A new genomic study in Science encompassing more than 300 genomes spanning the last 50,000 years has revealed how a single wave of Neanderthal gene flow into early modern humans left an indelible mark on human evolution. scim.ag/4gkMvpz

scim.ag

Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans

Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 year...

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Vanderbilt Cell Imaging Shared Resource (CISR) @vucellimaging.bsky.social · 11/12/2024

It's that time of year. Confocal + Christmas = Xmas Tree, Ymas Tree, and our favorite Zmas tree. #microscopy #confocal #imaging

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Elliott Bernard @elliottbernard.bsky.social · 05/12/2024

Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...

cell.com

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Journal of Experimental Medicine @jem.org · 10/12/2024

New: Bernaleau et al. @rebsamenlab.bsky.social use a loss-of-function genetic screen to identify the ER-resident protein CCDC134 as an essential regulator of Toll-like receptor (TLR) responses. CCDC134 binds and stabilizes the TLR chaperone Gp96. buff.ly/3ZrE70d

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bioRxivpreprint @biorxivpreprint.bsky.social · 10/12/2024

Pol II degradation activates cell death independently from the loss of transcription www.biorxiv.org/content/10.1101/202…

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Victor J. Torres @torreslab.bsky.social · 15/11/2024

Publication Alert! Happy to share our new work published in CellReports of a collaboration with the Zychlinsky Lab (Max Planck Institute for Infection Biology). "Histone H1 kills MRSA". cell.com/cell-reports.... Enjoy!

cell.com

Histone H1 kills MRSA

Marsman et al. detect histone H1 in MRSA in human abscesses and demonstrate that it kills MRSA under physiological conditions. They identify through selective evolution and a genome-wide screen that h...

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Jesse Erasmus @jesseerasmus.bsky.social · 10/11/2024

Couldn’t find a virology starter pack so here’s one to get the ball rolling. Repost/reply if you are a virologist so I can find and add you to the list! go.bsky.app/SinqoJU

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