Reposted by Nath Joneskinetoplastids papers @kinetoplastpapers.bsky.social · 23/09/2026H2A.Z-H2B.V nucleosomes form a specialised scaffold for transcription initiation in Trypanosoma brucei www.biorxiv.org/content/10.64898/2026.09.18.752700v1 044
Reposted by Nath JonesJiménez-Ruiz Lab @jimenezruizlab.bsky.social · 10/03/2026PhD opportunity at LMU Munich 🇩🇪 Join our lab to study the molecular and cellular biology of Apicomplexan parasites, with a focus on the apical complex, motility regulation, and post-translational modifications. Apply: elena.jimenez@lmu.de job-portal.lmu.de/jobposting/6...job-portal.lmu.dePhD student (m/w/d) 035
Reposted by Nath JonesSebastian Shaw @millseba.bsky.social · 19/02/2026🚨 Postdoc position 🚨 I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026). Details & application: jobs.uzh.ch/job-vacancie.... Please share! 😊jobs.uzh.chUZH: PostdocThe newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl... 1810
Reposted by Nath JonesNature Communications @natcomms.nature.com · 02/02/2026#Microbiology The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear Here the authors clarify how bedaquiline works @jnblab.bsky.social @morwan.me #TBSky #antibiotics #AMR dlvr.it/TQjZ0W 33721
Reposted by Nath JonesNature Microbiology @natmicrobiol.nature.com · 02/02/2026go.nature.comBabesia divergens host cell egress is mediated by essential and druggable kinases and proteasesNature Microbiology, Published online: 27 January 2026; doi:10.1038/s41564-025-02238-7Analysis of Babesia divergens egress from host cells reveals druggable targets and identifies compounds for potential babesiosis treatment. 042
Nath Jones @drnathjones.bsky.social · 05/01/2026I am pleased to share our latest preprint, detailing the characterisation of BDF7 in Leishmania. This non-canonical bromodomain factor is essential for the parasite to live inside the host macrophage and has a parasite specific function compared to the host ortholog , ATAD2. Details in the link: 051
Reposted by Nath JonesParasitesRule @parasitesrule.org · 16/12/2025🦠 Grad students & postdocs in parasitology: Apply now for the Biology of Parasitism (BoP): Modern Approaches course at @MBLScience. Hands-on labs, expert lectures, and cutting-edge tools. 📅 Summer 2026 | ⏰ Deadline Feb 5 🔗 mbl.edu/courses 01415
Reposted by Nath JonesChris H. Hill @chillzaa.bsky.social · 13/11/2025🚨Attention prospective PhD students🚨 Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪 We have THREE fully-funded PhD projects available for October 2026 entry: www.findaphd.com/phds/?Keywor... Please share/repost, and get in touch if you're interestedfindaphd.comchris hill PhD Projects, Programmes & Scholarships - 3 PhDs ListedFindAPhD. Search Funded PhD Projects, Programmes & Scholarships in chris hill. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world. 01213
Reposted by Nath JonesLori Passmore @lapassmore.bsky.social · 27/09/2025We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM. Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩 #RNA #cryoEM 05952
Reposted by Nath JonesTea Tomita @teagondii.bsky.social · 17/09/2025[We are Hiring!] The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM. This project aims to unlock new strategies for treating toxoplasmosis. DM for more info! 074
Reposted by Nath JonesAndrew Maclean @macleanlab.bsky.social · 23/07/2025📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️ elxw.fa.em3.oraclecloud.com/hcmUI/Candid...elxw.fa.em3.oraclecloud.comPostdoctoral Research AssociateWe are looking for a talented and enthusiastic Postdoctoral researcher to join the Maclean lab to investigate the metabolism of the human parasite Toxoplasma gondii. 088
Reposted by Nath JonesHugo Belda @hbelda.bsky.social · 23/06/2025Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...nature.comThe fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature MicrobiologyFIKK effector kinases underwent rapid evolutionary expansion and are a druggable target in Plasmodium falciparum. 2237
Reposted by Nath JonesFaria Tryps Lab @fariatrypslab.bsky.social · 27/05/2025So happy to share the first preprint from our lab on post-transcriptional regulation at the VSG expression-site body in trypanosomes. @ybri-uoy.bsky.social @york.ac.ukbiorxiv.orgSpecialised RNA decay fine-tunes monogenic antigen expression in African trypanosomesAntigenic variation is a sophisticated immune evasion strategy employed by many pathogens. Trypanosoma brucei expresses a single Variant-Surface-Glycoprotein (VSG) from a large genetic repertoire, whi... 13112
Reposted by Nath JonesRobin Allshire 🇮🇪 🇪🇺✊🏿 ⬆️ Zak’s favourite nucleosome: K9me @allshire-lab.bsky.social · 24/04/2025Our latest collaborative work with Keith Matthews’ lab using synthetic DNA binding proteins to explore the chromatin protein contexts of repetitive sequences in Trypanosoma brucei in now on bioRxiv - thanks to all involved! 2025.04.22.649942; doi: doi.org/10.1101/2025...doi.orgDefining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteinsKinetoplastids, such as Trypansoma brucei, are eukaryotes that likely separated from the main lineage at an exceptionally early point in evolution. Consequently, many aspects of kinetoplastid biology ... 0113
Reposted by Nath JonesDimitris Lagos @dimitrislagos.bsky.social · 22/04/2025We have a 3-year PDRA post in Cancer Immunogenomics. Ideal to use and strengthen your bioinformatics skills to discover how cancer transcriptome quirks shape immunotherapy outcomes. Funded by @cancerresearchuk.org. It’ll be fun! jobs.york.ac.uk/vacancy/rese... @hyms.ac.uk @ybri-uoy.bsky.socialjobs.york.ac.ukJobs - The University of York 097
Reposted by Nath Jonesveupathdb.org @veupathdb.org · 21/04/2025Keep VEuPathDB open-access to all by subscribing today! veupathdb.org/veupathdb/ap... 11616
Reposted by Nath JonesÁlvaro Acosta Serrano @aacostaserrano.bsky.social · 26/03/2025Glad this is finally out. Using pharmacokinetic modeling we show that #nitisinone, an FDA-approved drug 4 #Tyrosinemia & #Alkaptonuria, kills #Anopheles mosquitoes, outperforming #Ivermectin. Grateful to all primary author’s & fantastic collaborators! www.science.org/doi/10.1126/...science.orgAnopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinoneNitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism. 0166
Nath Jones @drnathjones.bsky.social · 04/03/2025New preprint: results from a collaborative project funded by the GCRF Global Network for NTDs investigating Leishmania deubiquitinase 16 as a potential drug target. @ybri-uoy.bsky.social @mottramlab.bsky.social www.biorxiv.org/content/10.1...biorxiv.orgStructure and Activity of the Essential UCH Family Deubiquitinase DUB16 from Leishmania donovaniIn Leishmania parasites, as for their hosts, the ubiquitin proteasome system is important for cell viability. As part of a systematic gene deletion study, it was discovered that four cysteine protease... 032
Reposted by Nath JonesAbhinay Ramaprasad @abhinay.bsky.social · 17/01/2025🥁🥁 Job alertttt!! Interested in weird biology of malaria parasites? Inducible genetic screens? Single-cell RNAseq? Come postdoc with us - www.parafugelab.com ! International applicants or applicants just finishing up their PhD, both welcome!! www.jobs.gla.ac.uk/job/research...jobs.gla.ac.ukResearch Assistant/AssociateJob Purpose We are seeking to recruit a motivated and creative Research Assistant/Associate (postdoctoral researcher) to work within an MRC-funded research programme https://gtr.ukri.org/projects?... 12520
Reposted by Nath JonesWillem van Schaik @wvschaik.bsky.social · 22/01/2025Is there a way to download all of NIH Bioart (in case it is taken offline by the current regime in the USA)? bioart.niaid.nih.gov/discoverbioart.niaid.nih.govBioart 3137
Reposted by Nath JonesDaniela Barillà @danielabarilla.bsky.social · 03/12/2023MRC- funded PhD project at the interface between biology & physics to investigate the segregation of an antibiotic resistant plasmid. Interdisciplinary training with super supportive supervisors. In the beautiful historic city of York. Please re-post, thanks! #microsky 🦠🧫🧪 📆17 December 0813
Nath Jones @drnathjones.bsky.social · 01/11/2023Happy to see this now online at ACS Infectious Diseases . Catherine & the team did a great job on the initial structural & biophysical assessment of BDF5 bromodomains as potential drug targets in Leishmania. #parasite #epigenetics t.co/UoI9i1NSux 020