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Álvaro Acosta Serrano

@aacostaserrano.bsky.social
224 followers 295 following 11 posts

Professor of Vector Biology and Parasitology at the University of Notre Dame, USA

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Reposted by Álvaro Acosta Serrano
Dr Joanne Power @hanniepower.bsky.social · 11/09/2025
Save the dates!! @bspparasitology.bsky.social Spring Meeting 2026 will be in Bonnie Glasgow! 7-9 April 2026, with a drinks reception in Glasgow City Chambers on the 6th of April 2026! Keep an eye on the BSP website for registration and abstract submission! Logo by @shannaraeilean.bsky.social! 🦟
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Reposted by Álvaro Acosta Serrano
Zachary Stavrou - Dowd @zstavdowd.bsky.social · 11/08/2025
Marvel hasn’t called yet, but “Mosquito Slayer: Origin” has a nice ring to it..... Thank you for covering our work @aacostaserrano.bsky.social @lstmnews.bsky.social @notredame.bsky.social doi.org/10.1186/s130...
doi.org
The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
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Reposted by Álvaro Acosta Serrano
Ana Flores-Mireles @afloresmireles.bsky.social · 07/08/2025
Check out this awesome study from our Notre Dame colleagues, @aacostaserrano.bsky.social and Lee Haines!! Nitisinone kills insecticide-resistant mosquitoes through cuticular uptake parasitesandvectors.biomedcentral.com/articles/10....
parasitesandvectors.biomedcentral.com
The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
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Reposted by Álvaro Acosta Serrano
Zachary Stavrou - Dowd @zstavdowd.bsky.social · 07/08/2025
Just out: LSTM’s blog post on our latest paper exploring how nitisinone kills malaria mosquitoes, even the resistant ones, through tarsal contact. From rare disease drug to vector control tool. @aacostaserrano.bsky.social 📄 Paper: doi.org/10.1186/s130... #malaria #vectorcontrol #entomology #HPPD
doi.org
The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 01/08/2025
Here we show that #nitisinone kills insecticide-resistant mosquitoes via cuticular uptake. Great work Zach Stavrou-Dowd, Lee Haines, & LITE. Thanks @gatesfoundation.bsky.social & @RoseTrees Trust @notredame.bsky.social @lstmnews.bsky.social parasitesandvectors.biomedcentral.com/articles/10....
parasitesandvectors.biomedcentral.com
The β-triketone, nitisinone, kills insecticide-resistant mosquitoes through cuticular uptake - Parasites & Vectors
Background Insecticide resistance in disease-transmitting arthropods of agricultural, veterinary, and public health significance poses a significant threat to vector control programs worldwide. Previo...
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Reposted by Álvaro Acosta Serrano
Kristin Michel @kmichel.bsky.social · 02/05/2025
New paper from the lab: Bianca Morejon defines the regulatory protease network that governs #mosquito #immunity www.pnas.org/doi/10.1073/...
pnas.org
The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression | PNAS
Serine protease cascades regulate key innate immune responses. Their activation cleaves a series of inactive protease zymogens, which then activate...
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 16/04/2025
theconversation.com/ivermectina-...
theconversation.com
Ivermectina y nitisinona: las dos últimas armas antimosquitos para luchar contra la malaria
La creciente resistencia de los plasmodios y de sus mosquitos vectores frente a fármacos e insecticidas está incentivando la elaboración de nuevas herramientas terapéuticas contra la malaria.
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 11/04/2025
www.thenakedscientists.com/articles/int... Many thanks to Chris Smith and the @NakeScientists for the short podcast about our recent publication on #Nitisinone & #Anopheles #mosquitoes
thenakedscientists.com
Safe human drug can poison mosquitoes
Another potential mitigation for malaria...
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Reposted by Álvaro Acosta Serrano
Heather Ferguson @drheatherferg.bsky.social · 03/04/2025
Good news - after 76 yrs with no new drug for rhodiensese Human African Trypanosomiasis, @who.int has faciliated research, development & now delivery ofmore effective fexinidazole to replace suramin & melarsoprol. Huge benefit given harsh side effects of the latter. www.who.int/news/item/07...
who.int
WHO delivers fexinidazole to Malawi and Zimbabwe – a long-awaited safer treatment for rhodesiense human African trypanosomiasis
In a major breakthrough for rhodesiense human African trypanosomiasis (r-HAT) treatment, in August 2024 WHO recommended fexinidazole to replace suramin and melarsoprol as the first-line treatment for ...
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 28/03/2025
Thanks Jason Bittle & National Geographic @hgl7.bsky.social 4 the nice piece www.nationalgeographic.com/science/arti... about our recent paper on nitisinone & malaria control www.science.org/doi/10.1126/...
nationalgeographic.com
To fight malaria, scientists want to poison mosquitoes—with human blood
Low doses of a drug already approved for treating rare genetic conditions in humans kills mosquitoes dead. Scientists say it could be a valuable new tool in the fight against disease.
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 28/03/2025
Thanks @freddyfrischknecht.bsky.social it has been a long road, as usual…
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Reposted by Álvaro Acosta Serrano
Antonio Martínez Ron @aberron.bsky.social · 27/03/2025
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la lucha contra la malaria
eldiario.es
Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la...
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 28/03/2025
A team effort!
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 27/03/2025
Muchas gracias @elenagomez-diaz.bsky.social y Carlos!
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Reposted by Álvaro Acosta Serrano
Antonio Martínez Ron @aberron.bsky.social · 26/03/2025
Ya para socios: Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
eldiario.es
Un nuevo compuesto prometedor contra la malaria: convierte tu sangre en veneno para los mosquitos
Un grupo de investigadores descubre que la nitisinona, que ya se emplea como fármaco contra enfermedades raras, es más eficaz contra los mosquitos que la ivermectina y podría ser una alternativa en la...
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Álvaro Acosta Serrano @aacostaserrano.bsky.social · 26/03/2025
Glad this is finally out. Using pharmacokinetic modeling we show that #nitisinone, an FDA-approved drug 4 #Tyrosinemia & #Alkaptonuria, kills #Anopheles mosquitoes, outperforming #Ivermectin. Grateful to all primary author’s & fantastic collaborators! www.science.org/doi/10.1126/...
science.org
Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone
Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine catabolism.
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Reposted by Álvaro Acosta Serrano
mara lawniczak @marakat.bsky.social · 24/02/2025
globally, there are ~3500 described mosquito species in the Culicidae family and many of these are important vectors of disease but only a small percentage have genomic resources. we are launching a pilot project to generate high quality reference genomes for 100 important mosquito species [1/3]
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Reposted by Álvaro Acosta Serrano
PLOS Biology @plosbiology.org · 21/02/2025
PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry. plos.io/3D4O8cH
plos.io
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
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Reposted by Álvaro Acosta Serrano
Heather Ferguson @drheatherferg.bsky.social · 19/02/2025
'I log on & am bombarded by pictures of things happening outside of Burundi..A non-elected billionaire is answering qs in the Oval Office. He is well-fed & cost of his clothing alone could probably sustain the children in my hospital for a yr. I wonder how we will feed the malnourished babies 2mrw'
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Reposted by Álvaro Acosta Serrano
Science Magazine @science.org · 10/02/2025
Breaking news: 22 states are suing to block NIH’s cutting of indirect costs. See our updated story on the Friday night news and its aftermath. scim.ag/4hTJQ6v
scim.ag
NIH slashes overhead payments for research, sparking outrage and lawsuit
Move to cut indirect cost rate to 15% could cost universities billions of dollars
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Reposted by Álvaro Acosta Serrano
Felipe H Santiago-Tirado @felipehst.bsky.social · 10/02/2025
Hey #fungal people - the applications for this years MOMY course are open! Wonderful course in a wonderful place with wonderful people. Check it out here: www.mbl.edu/education/ad...
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Reposted by Álvaro Acosta Serrano
Ryan Smith @vectorimmunity.bsky.social · 06/02/2025
🚨 We are recruiting for two post-doc positions!🚨 1) Development of genetic tools to study mosquito immune cells isu.wd1.myworkdayjobs.com/IowaStateJob... 2) Role of mosquito immune cells in immune recognition and priming isu.wd1.myworkdayjobs.com/IowaStateJob...
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Reposted by Álvaro Acosta Serrano
Siegel Lab @siegel-lab.bsky.social · 16/01/2025
I’m very much looking forward to attending the symposium and to celebrate the career of Mark Carrington.
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