UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

An interview by Dr Ashleigh Wilcox with Professor Neil Evans, Professor Helen Christian, Dr Chinedu Udeh-Momoh about being an early career researcher during the COVID-19 pandemic and how a mentor can help.

The current obesity drug landscape, dominated by GLP-1 receptor agonists and emerging multi-agonist therapies, has reinforced that long-term weight loss is achieved in large part through central mech...

A key role for retrograde neuromodulatory signalling in motivated behaviour is shown through dynamic endocannabinoid release within a thalamostriatal circuit that regulates behavioural engagement during reward seeking.

Jarvie et al. identify two populations of parabrachial CGRP neurons, one that responds rapidly to appetitive signals during ingestion and the other that responds slowly to aversive visceral cues. The rapid CGRP neuron activation during ingestion is shown to be required for post-ingestive learning but not, as previously believed, satiety.

Glutamate cotransmission predicts the behavioral functions and characteristics of dopaminergic neurons in the VTA.

When preparing a scientific paper, we typically write with coauthors who have different backgrounds and styles, and we target readers who have little time and patience. To help both readers and writer...

Neurons have long taken top billing in memory, but researchers are making the case for astrocytes.

Gut–brain signalling, inspired by the Review starting on p608

Apply for the Lecturer / Associate Professor in Primate or Human Evolutionary Anatomy role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

Food intake is governed by two interacting drives. The homeostatic hunger drive regulates food intake to fulfill caloric needs while the hedonic drive promotes intake of palatable foods outside of cal...

Fernández-Peña et al. used viral intersectional tools to selectively target epinephrine-expressing C1 neurons in mouse rostral ventrolateral medulla (RVLM). Adjusting their activity altered the severi...

What do randomized controlled trials really tell us about the effects of ultraprocessed foods?

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

PhD Project - Alpha-Synuclein Condensates and Synaptic Dysfunction in Parkinson’s Disease at University College London, listed on FindAPhD.com

Nuclei within the limbic system like the central amygdala (CeA) play a critical role in mediating fear, motivation, reward, and appetitive behavior. A…

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

An AAV-based circuit modulation approach that consists of a designer retrograde AAV capsid, a medium spiny neuron-enriched promoter, and a selected chemogenetic effector specifically modulates direct ...

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Nature Metabolism - Semaglutide-induced weight loss is shown to depend on Gs-coupled signalling in GLP1R-expressing hindbrain neurons, with a critical role for cAMP in mediating neuronal activation...

Incretin-based therapies are transforming the treatment of obesity and related comorbidities. This Review outlines the current landscape of obesity drug development, focusing on glucagon-like peptide ...

Nature Metabolism, Published online: 22 May 2026; doi:10.1038/s42255-026-01534-8Semaglutide-induced weight loss is shown to depend on Gs-coupled signalling in GLP1R-expressing hindbrain neurons, with a critical role for cAMP in mediating neuronal activation and downstream effects.