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Sebastian Bruchmann

@doktorbasti.bsky.social
551 followers 380 following 13 posts

Assistant Research Professor @ University of Cambridge / HLRI Functional Genomics, AMR and Host Pathogen Interactions of Klebsiella pneumoniae and Pseudomonas aeruginosa sebbruchmann.github.io

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Reposted by Sebastian Bruchmann
Ben Vezina @bananabenana.bsky.social · 29/01/2026
This is the sort of strategic planning that should go into #vaccine design 💉 They analysed 1,930 #Klebsiella pneumoniae 🦠🧫🧬 neonate blood isolates from 13 countries and estimate that 20 antigens 🧪 could cover 72.9% of all infections for 5–10 years #IDSky #EpiSky journals.plos.org/plosmedicine...
journals.plos.org
Distribution of capsule and O types in Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: A meta-analysis of genome-predicted serotype prevalence to inform potential vaccine cover...
Thomas Stanton and colleagues use whole genome sequencing to evaluate the prevalence of Klebsiella pneumoniae K and O antigen types in 13 countries in Africa and South Asia to help inform vaccine desi...
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 05/01/2026
🔊 Job Opportunity: Postdoctoral Research Fellow in Bacterial Evolution. Looking to recruit a postdoc to join a UKRI FLF-funded project on antibiotic resistance evolution in the microbiome 🦠 3 years funding, deadline 26th Jan, please share! hrwebapp.qub.ac.uk/tlive_webrec...
hrwebapp.qub.ac.uk
Job profile
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sylvain Brisse @sylvainbrisse.bsky.social · 30/11/2025
Huge preprint if you are interested in bacterial strain taxonomy! The why and how of cgMLST LIN codes: An extensively revised and expanded version doi.org/10.1101/2024... I will summarize it for you in this thread 👇
doi.org
Life Identification Numbers: A bacterial strain nomenclature approach
Unified strain taxonomies are needed for the epidemiological surveillance of bacterial pathogens and international communication in microbiological research. Core genome multilocus sequence typing (cg...
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Guillaume Méric @gmeric.bsky.social · 12/11/2025
New PhD position in my lab at @uniofbath.bsky.social (with both @tweethinking.bsky.social & Dr Bethan Littleford-Colquhoun)! We're looking for someone keen on bioinformatics and microbiome evolution. Important info below on eligibility & URSA competition funding👇 www.findaphd.com/phds/project...
findaphd.com
The overlapping microbiome: ecology, function and resilience beyond species boundaries at University of Bath on FindAPhD.com
PhD Project - The overlapping microbiome: ecology, function and resilience beyond species boundaries at University of Bath, listed on FindAPhD.com
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Christina Zielinski @zielinskilab.bsky.social · 05/11/2025
We are hiring! 🎓🧫 🧬 #PhD studentship available in #Immunology at #CambridgeUniversity to investigate a new killer function of human T cells. 📅 Application deadline: 3rd December 2025 more information: lnkd.in/dxq6yMay #findaPhD @ERC_Research
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Gemma Langridge @gemma-langridge.bsky.social · 28/10/2025
🚨 Another funded PhD alert🚨 We are recruiting again! For a PhD student to start with us in the @langridgelab.bsky.social October 2026 - please share 👀 If you are interested in foodborne pathogens, public health and phage, look no further 🦠🏥🧬 ➡️ tinyurl.com/3zvavp2t ⬅️ Apply by 6 Jan 2026 🗓️
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Sebastian Bruchmann @doktorbasti.bsky.social · 26/09/2025
Fantastic paper: "Dual transposon sequencing profiles the genetic interaction landscape in bacteria" out now in Science www.science.org/doi/10.1126/...
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Zamin Iqbal @zaminiqbal.bsky.social · 25/09/2025
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n
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James McInerney @jomcinerney.bsky.social · 25/09/2025
OK, here it is. Come work with me at the University of Liverpool making ALL THE AI models from ALL THE prokaryote pangenome data. Heck, we will make models from ALL the pangenomes, even eukaryotes!!! (link below👇) 1/4
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James McInerney @jomcinerney.bsky.social · 25/09/2025
PLEASE RETWEET.
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Sam Lipworth @samlipworth.bsky.social · 23/09/2025
Come and work with Nicole Stoesser and I in Oxford with the fantastic team @modmedmicro.bsky.social - great opportunity for a postdoc in microbial genomics to do some creative research with great datasets as part of our HPRU. my.corehr.com/pls/uoxrecru...
my.corehr.com
Job Details
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Sebastian Bruchmann @doktorbasti.bsky.social · 16/09/2025
Had a brilliant time in Liverpool at Edge Hill University for the Galleria mellonella Workshop 🐛 Grateful to be invited as a speaker, the great chats and new connections. Amazing to see the wide range of applications, hope our time lapse imaging work can add to the field!
Me (Sebastian Bruchmann) giving a presentation titled "Towards a scalable platform for high-throughput virulence assays"
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Eduardo Rocha @epcrocha.bsky.social · 08/09/2025
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
pasteur.fr
Pasteur-Paris University International doctoral program​ (PPU)
OverviewIn 2009, the Institut Pasteur, the world leading biomedical research institute founded by Louis Pasteur in 1887, inaugurated the Pasteur Paris-University (PPU) international doctoral program i...
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Centre for Genomic Pathogen Surveillance @thecgps.bsky.social · 22/04/2025
Our latest preprint is out describing amr.watch - a platform for monitoring AMR trends from global genomics data: www.biorxiv.org/content/10.1... (1/6)
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Olaya Rendueles @olayarendueles.bsky.social · 09/04/2025
Our review on recent advances in #PhageTherapy against Klebsiella pneumoniae is out! We analyze KP-phage interactions from an eco-evo perspective, summarize many lab and clinical trials, and discuss novel approaches like genetic engineering & machine learning. #microsky doi.org/10.1371/jour...
doi.org
Phage therapy for Klebsiella pneumoniae: Understanding bacteria–phage interactions for therapeutic innovations
Klebsiella pneumoniae (KP) is a Gram-negative bacterium that commonly resides in the human gastrointestinal tract and can also act as an opportunistic pathogen and cause extra-intestinal infections. K...
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Andries van Tonder @andriesvt.bsky.social · 06/03/2025
I've spent some time updating my two Nextflow-based bacterial QC pipelines (bacQC and bacQC-ONT). It'd be great to get some feedback. github.com/avantonder/b... github.com/avantonder/b...
github.com
GitHub - avantonder/bacQC-ONT: QC pipeline for ONT data
QC pipeline for ONT data. Contribute to avantonder/bacQC-ONT development by creating an account on GitHub.
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Brochado Lab @brochadolab.bsky.social · 20/02/2025
Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe! www.cmfi.uni-tuebingen.de/mariecuriephd
endamr.eu
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Pathogenwatch @pathogenwatch.bsky.social · 12/02/2025
We’ve just released a public Pathogenwatch collection of the MRSN Diversity Panel comprising 100 diverse K. pneumoniae clinical isolates: pathogen.watch/collection/8... #KlebClub
pathogen.watch
Pathogenwatch
A global platform for genomic surveillance.
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Michael Brockhurst @brockhurstlab.bsky.social · 06/02/2025
🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution @mermanchester.bsky.social Join us! #microsky www.jobs.manchester.ac.uk/Job/JobDetai...
jobs.manchester.ac.uk
Research Associate in Experimental Evolution:Manchester
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Audrey Goman, PhD @audrey-goman.bsky.social · 22/01/2025
✨ Excited to share our work in the Journal of Extracellular Vesicles! ✨ We reveal a new family of virulence factors in gram-negative bacteria like P. aeruginosa that drive harmful OMV production. 🦠 isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
isevjournals.onlinelibrary.wiley.com
Uncovering a new family of conserved virulence factors that promote the production of host‐damaging outer membrane vesicles in gram‐negative bacteria
CprA is a short-chain dehydrogenase/reductase (SDR) that contributes to resistance against colistin and antimicrobial peptides. The cprA gene is conserved across Pseudomonas aeruginosa clades and its....
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Infect-Net @infect-net.bsky.social · 24/01/2025
Sie suchen #Infektionsforscherinnen? Wir haben ein #StarterPack mit allen Infect-Net-Wissenschaftlerinnen auf BlueSky zusammengestellt: 🇬🇧 Curious about contributions of women in #infection research? We put together a StarterPack with all our Infect-Net experts on BlueSky 🦋 👉 go.bsky.app/JU8KaeQ
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Sebastian Bruchmann @doktorbasti.bsky.social · 15/01/2025
Great collection of papers on adaptive evolution of AMR
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Torsten Seemann @torstenseemann.bsky.social · 13/01/2025
Don't know who to follow for the best in microbial bioinformatics? This is the Starter Pack you need! bsky.app/starter-pack...
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Heather Hendrickson @drhhnz.bsky.social · 09/01/2025
Application review for the 2025 Gordon Research Conference on Microbial Population Biology begins on Jan 20. Maximize your chance of acceptance and $ support by submitting your application with a poster abstract before that date! Details: www.grc.org/microbial-po...
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Andrew Page @andrewjpage.bsky.social · 10/01/2025
I'm putting together a Microbial Bioinformatics starter pack to help get everyone connected in our community. Let me know if there are any bluesky users to be added and share so that twitter refugees can tune back in to the fantastic world microbes go.bsky.app/3ezLo7e
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Olaya Rendueles @olayarendueles.bsky.social · 09/01/2025
Join us for a new season of #KlebCkub! @klebclub.bsky.social New speakers & new research! Registration is FREE but mandatory. Abstracts due by February 16! Please share ! Link below👇🏻👇🏻
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Microbiology Society @microbiologysociety.org · 08/01/2025
It’s official: The Microbiology Society is on Bluesky!
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Mark Pallen @mjpallen.bsky.social · 03/12/2024
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.
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Tom Stanton @tomstantonmicro.bsky.social · 21/11/2024
Don't forget to join the #KlebClub Slack workspace! #Klebsiella #KLEBS2024 join.slack.com/t/klebclub/s...
join.slack.com
Slack
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Kat Holt @katholt.bsky.social · 20/11/2024
A small history lesson in #Klebsiella genomics in honour of #KLEBS24… 2009 was a big year for Klebs! - First genome published - First description of ST258 KPC-producing clone pubmed.ncbi.nlm.nih.gov/19218573/ - First description of NDM-1 beta-lactamase pubmed.ncbi.nlm.nih.gov/19770275/
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Ben Vezina @bananabenana.bsky.social · 21/11/2024
(1/6) Our new short paper on incidental bacterial domestication between patient isolation and creation of frozen stock. Geno/phenotype changes are obscured by rich media and more prevalent than we previously thought. #MicroSky
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Marit Hetland @genomarit.bsky.social · 12/09/2024
Excited to share this preprint where we’ve used genomic analysis of >3000 genomes to study Klebsiella pneumoniae in a One Health perspective 🦠🔬👩‍💻 #OneHealth #KLEBGAP #KlebClub #IrenLöhr @katholt.bsky.social #NORKLEBNET
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Klebsiella Club @klebclub.bsky.social · 17/11/2024
Lots of people are missing, let us know if you want to be included by replying! You can also share to help us gain visibility #MicroSky go.bsky.app/EdereoU
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Eduardo Rocha @epcrocha.bsky.social · 15/12/2023
New postdoc position in our lab for a project led by Marie Touchon (bioinformatics) and with O Tenaillon (experiments) on the evolution and dynamics of microbial genomes to understand their diversification by gene flow. Check research.pasteur.fr/en/job/postd...
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Sebastian Bruchmann @doktorbasti.bsky.social · 14/12/2023
Note to self: No need to remove read duplicates in RNA-seq experiments! "Samples of input amounts greater than 125 ng had a negligible PCR duplication rate and the number of PCR cycles did not have a significant effect on data quality" www.biorxiv.org/content/10.1...
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Zamin Iqbal @zaminiqbal.bsky.social · 19/10/2023
PhD studentship (co-sup with Ed Feil, collaborators incl. Edze Westra): using GWAS to find bacterial susceptibility loci to phage infection, and machine learning for prediction. Amazing dataset, great application for machine learning www.findaphd.com/phds/project...
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Alison Mather @alisonmather.bsky.social · 19/10/2023
PhD opportunity with me and Mark Webber! Some microbial genomics, some molecular biology, all fun. Apply here: buff.ly/3FjzrzS
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