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Diane Takahashi

@diane-takahashi.bsky.social
168 followers 216 following 31 posts

Structural biologist in IGBMC (France) studying Transcription and DNA topology. Opinions are my own She/Her

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Reposted by Diane Takahashi
Kate Beckham @kshbeckham.bsky.social · 03/08/2026
Happy to share our recent story on the Type VII secretion system. Here were present new insights into the regulation of secretion mediated by the central pore. Thanks to all authors involved in the work. 🙂
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Kathrin Leppek @katleppek.bsky.social · 01/08/2026
It's an RNA World. We just live in it. Happy World RNA Day!
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Septima P. Snark @drsubini.blacksky.app · 31/07/2026
Dr. Tiffany Willoughby-Herard put her body on the line to protect students fighting for Gaza & police assaulted her. Instead of protecting her, UC Irvine has stripped her faculty role & her health benefits. Please sign petition, write a letter, signal boost robindgkelley.substack.com/p/in-support...
robindgkelley.substack.com
In Support of Dr. Tiffany Willoughby-Herard
Most academics in the U.S., as well as activists resisting the genocide in Gaza, are familiar with the case of Professor Tiffany Willoughby-Herard, a renowned Global Studies scholar at the University ...
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Nancy Levine Stearns @nancylevinestearns.bsky.social · 01/08/2026
🚨 ABC News: The Johns Hopkins University researcher released after being detained by ICE at Maryland airport: Fatima Ameaka was held at a facility in Louisiana, according to her lawyer. The ICE kidnappings must stop. abcnews.com/US/johns-hop...
abcnews.com
Johns Hopkins researcher released after being detained by ICE at Maryland airport
A Johns Hopkins University researcher, originally from Cameroon, was detained by Immigration and Customs Enforcement officers earlier this week.
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David McQuarrie @davidmcquarrie.bsky.social · 01/08/2026
A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins doi.org/10.1093/nar/...
doi.org
A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins
Abstract. Efficient purification of specific RNAs from lysates remains a major challenge. Existing methods, such as MS2 tagging or oligonucleotide hybridiz
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Reposted by Diane Takahashi
SK Winnicki, PhD 🏳️‍⚧️ @skwinnicki.bsky.social · 22/01/2025
Here is a photo of a trans non-binary biologist (me) holding a bird (Eastern Towhee) that is likely a bilateral gynandromorph-- a fusion of cells with female-type chromosomes and cells with male-type chromosomes in one bird! Biological sex and human gender diversity is real and wonderful ❤️🏳️‍⚧️
Photo of SK in a forest in Pennsylvania, wearing a tie dyed field shirt from the 2017 grassland bird Konza Crew and holding a large sparrow that is black on one side of the body and brown on the other.
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Molecular Cell @cp-molcell.bsky.social · 11/03/2025
The RNA helicase HrpA rescues collided ribosomes in E. coli
dlvr.it
The RNA helicase HrpA rescues collided ribosomes in E. coli
Antibiotics that inhibit ribosomes lead to collisions on mRNAs when upstream ribosomes catch up with stalled ones. Campbell et al. show that the HrpA protein in E. coli senses ribosome collisions and removes the stalled ribosome, helping cells survive in…
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Reposted by Diane Takahashi
🎃 Imani Gandy Corn 🎃 @angryblacklady.blacksky.app · 06/03/2025
THere’s something like 5 k-12 trans athletes in the country. FIVE. Please stop pretending like this is some dire concern from people who really give a shit about women’s sports. I’m begging you to stop being distracted by these ceaseless attacks on trans people.
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Diane Takahashi @diane-takahashi.bsky.social · 25/02/2025
I had a nice time in America last time I went. I didn't know it was going to be my very last time there.
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Alejandra Caraballo @esqueer.net · 25/02/2025
NEW: Fully leaked diplomatic cable directing the implementation of this policy at all US diplomatic and consular posts.
GPT-4o

This image is a document from the U.S. Department of State with the subject "Guidance to Visa-Issuing Posts on January 20 Executive Order 14168 on Defending Women from Gender Ideology Extremism and Restoring Biological Truth to the Federal Government." It outlines an action request and provides a summary and definitions related to sex and gender as per the executive order (E.O.). The document mandates that sex listed on visas must correspond to the biological sex at birth and instructs the use of the term 'sex' rather than 'gender' in federal policies and documents.GPT-4o

This image is a continuation of a document from the U.S. Department of State. It details the implementation of changes to ensure government-issued identification documents, like passports and visas, reflect the holder's sex as defined by an executive order. It states that foreign passports should be considered as evidence of the applicant’s sex but may require confirmation if discrepancies are noticed. The document outlines the process for consular officers to follow when there is a discrepancy in sex markers. It also provides action requests for updating public instructions on visa applications, specifying the requirement to select sex at birth. Existing U.S. visas that do not comply with this guidance remain valid until expiration.GPT-4o

This image is the final part of a document from the U.S. Department of State regarding guidance on an executive order about recognizing sex on government-issued documents. It explains that existing visas remain valid until expiration despite sex marker differences. The document mentions forthcoming updates to FAM guidance and outlines talking points for interacting with applicants. It reaffirms the policy to list sex, not gender identity, on U.S. visas. Additional guidance can be accessed via specified web resources. It includes contact emails for media and congressional inquiries, and is signed by various personnel involved in drafting, clearing, approving, and releasing the document.
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Diane Takahashi @diane-takahashi.bsky.social · 25/02/2025
If you are Trans living in the fascist country, and you can leave, please do.
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Diane Takahashi @diane-takahashi.bsky.social · 09/02/2025
In the midst of all the Transphobia, please know our lab is safe for Trans people.
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IGBMC @igbmc.bsky.social · 28/01/2025
L'IGBMC rejoint Bluesky ! Bienvenue sur le compte officiel de l'Institut de Génétique et de Biologie Moléculaire et Cellulaire ! Suivez-nous pour découvrir nos découvertes scientifiques, nos collaborations internationales et les coulisses de notre institut. #IGBMC #Science #Recherche #Innovation
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Art Candee 🍿🥤 @artcandee.bsky.social · 04/02/2025
Senator Raphael Warnock ahead of the vote on RFK Jr. for HHS Secretary: "I simply do not trust him to oversee the CDC. He's unqualified, and I dare say that everybody here knows it." BOOM! 🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥
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Solomon @solomonrmissouri.com · 04/02/2025
But when the discussions of critical race theory… diversity… equity… and inclusion were being had… you read “race” but you heard “Black”
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Diane Takahashi @diane-takahashi.bsky.social · 04/02/2025
Congratulations to @mohammadafsarkhan.bsky.social for getting the best talk award !!!!
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Diane Takahashi @diane-takahashi.bsky.social · 04/02/2025
Department retreat in Mt Saint Odile
A picture of the sunrise in a mountain area with a sea of clouds
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Diane Takahashi @diane-takahashi.bsky.social · 29/01/2025
BREAKING: ICE just announced it is pausing the hotline where people can call to report undocumented immigrants because 90% of the calls are from people reporting Elon Musk.
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Christine Cucinotta @chrstne.bsky.social · 28/01/2025
trans rights are human rights. i hate this administration
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Krystle J McLaughlin @biophyskrys.bsky.social · 25/11/2024
Hi! Happy for all the new followers- allow me to (re)introduce myself: I'm an assistant professor in chemistry at Vassar College, originally from Trinidad & Tobago 🇹🇹! I teach biochemistry & biophysical chemistry, & study bacterial proteins using x-ray crystallography. #krystlethecrystallographer
Picture of Krystle McLaughlin sitting at microscope in a lab.
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Diane Takahashi @diane-takahashi.bsky.social · 29/01/2025
Please consider moving to Europe if you are a Trans researcher living in the US. There are no safe places, but most countries apart from the UK are better than the US right now.
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Diane Takahashi @diane-takahashi.bsky.social · 21/01/2025
How is Musk doing Nazi salutes not the main news ??????
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Diane Takahashi @diane-takahashi.bsky.social · 20/01/2025
Today is a hard day for Trans people living in America. And sadly, it is going to remain the case for a while. Sending all my support to them.
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Diane Takahashi @diane-takahashi.bsky.social · 16/01/2025
What I find truly amazing, is the idea that by "simply" plunging the grid in liquid ethane at high speed it works. I would have thought it involved pressure, and complex systems, not a robotic arm !
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Karolin Luger @nucleosomepolice.bsky.social · 16/01/2025
by now you probably know that #giantviruses have #histones, but some also have histone variants! Check out our latest preprint on an essential H2B-H2A histone variant in Melbournevirus - a fantastic collaboration with the Abergel Lab, spearheaded by Ale Villalta. www.biorxiv.org/content/10.1...
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Institut Pasteur | 130 years of biomedical research @pasteur.fr · 16/01/2025
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋 The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
pasteur.fr
Institut Pasteur decides to leave X
The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...
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Milo B. Fasken, Ph.D. @milofasken.bsky.social · 14/01/2025
#tRNA #Ribosome #Asite #StopCodon #Readthrough #Scerevisiae www.nature.com/articles/s41...
nature.com
Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough - Nature Structural & Molecular Biology
Transfer RNAs (tRNAs) serve as a dictionary for ribosomes translating the genetic message from mRNA into protein. Here, the authors show that understanding specific interactions of tRNAs in the riboso...
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Diane Takahashi @diane-takahashi.bsky.social · 15/01/2025
So many things to discover yet in the field of DNA topology in Archaea.
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Diane Takahashi @diane-takahashi.bsky.social · 15/01/2025
Every time I come back after sick leave, my plant is blooming. Apart from the fact that I feel particularly bad at taking care of plants, it is so nice of my colleague to take care of my plant while I am away. I have the best colleagues
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Diane Takahashi @diane-takahashi.bsky.social · 21/12/2024
Our lab is looking for PhD students ! Please check the following link if you are interested. There are 2 projects advertised on the structure/function of RNA polymerase from bacterial pathogens and structure/function of the coupling of mRNA transcription and splicing imcbio-phdprogram.unistra.fr
imcbio-phdprogram.unistra.fr
IMCBio International PhD Program
IMCBio International PhD Program - Application form
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Diane Takahashi @diane-takahashi.bsky.social · 21/12/2024
Our lab is looking for PhD students ! Please check the following link if you are interested. There are 2 projects advertised on the structure/function of RNA polymerase from bacterial pathogens and structure/function of the coupling of mRNA transcription and splicing imcbio-phdprogram.unistra.fr
imcbio-phdprogram.unistra.fr
IMCBio International PhD Program
IMCBio International PhD Program - Application form
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Reposted by Diane Takahashi
Amy Diehl, Ph.D. @amydiehl.bsky.social · 21/12/2024
Studies find mothers carry 71% of the mental load and a causal link between mental load and women's participation in public life. This load "takes up more space in their minds & crowds out the ability or desire to take on additional responsibility at work. fortune.com/2024/12/20/w...
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Manolis Maragkakis @manolis-maragkakis.bsky.social · 21/12/2024
Our paper out in eLife. Full-length direct RNA #nanopore sequencing uncovers 5' #RNA shortening upon cellular #stress that depends on ✅ stress-granules and #XRN1 but ❌ not poly(A) or cap removal elifesciences.org/articles/96284 🤔 useful to further reduce translational load during #ISR? #RNAbiology
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Reichow Lab @reichowlab.bsky.social · 06/12/2024
Super excited for this one! High-res #cryo-EM ensemble of sHSP/client complexes, uncovering 'Mechanism of small heat shock protein client sequestration and induced polydispersity' www.biorxiv.org/content/10.1... A teaser...👇
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Olivier Duss @olivierduss.bsky.social · 04/12/2024
First paper of our lab today @natureportfolio.bsky.social by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping! @embl.org #RNAbiology #RNASky t.co/a24Xxcxdo0
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Diane Takahashi @diane-takahashi.bsky.social · 06/12/2024
Impressive work !!!!
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Diane Takahashi @diane-takahashi.bsky.social · 02/12/2024
So nice!!!! I am going to print it!
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Diane Takahashi @diane-takahashi.bsky.social · 02/12/2024
Nice work published in our lab, together with Walter and Rappsilber labs on the coupling between Transcription and Translation. www.science.org/doi/10.1126/...
science.org
Molecular basis of mRNA delivery to the bacterial ribosome
Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...
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Ruben Gonzalez @rubenlgonzalez.bsky.social · 30/11/2024
Amazing work revealing the mechanisms by which mRNAs are delivered to the bacterial ribosome! 🤯 Congrats to the Weixlbaumer lab and their collaborators in the Walter and Rappsilber labs! 🍾
science.org
Molecular basis of mRNA delivery to the bacterial ribosome
Protein synthesis begins with the formation of a ribosome-messenger RNA (mRNA) complex. In bacteria, the small ribosomal subunit (30S) is recruited to many mRNAs through base pairing with the Shine-Da...
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Diane Takahashi @diane-takahashi.bsky.social · 26/11/2024
Now I need to find back my topoisomerase colleagues...
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Diane Takahashi @diane-takahashi.bsky.social · 26/11/2024
Now that structural biologists are here, we can restart the ccp4 mailing list? I used to be impressed with people who managed to follow the very dense feed.....
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