The amount of viral epitope presented on MHC I in lymphoid tissue of infected mice is a correlate of CD8+ T cell immunogenicity.

Loss-of-function MDA5 variants increase the risk of chronic inflammation but protect against autoimmune disease. Singh et al. show that autoimmune-protective variants impair MDA5 signaling via differe...

Scientists from all over the world have been racing to understand the fundamentals of Devil Facial Tumour Disease and find a way to stop it. One of them is Yi Ning (Sabrina) Fu, a recent Honours gradu...

Nature - Bovine H5N1 binds poorly to human-type sialic acid receptors

Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines elicit robust CD4+ T cell responses, which are essential for antiviral immunity. While peptides presented to CD4+ T cells via ma...

PubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications…

Nature Medicine - Genomic and epidemiologic data suggest that the rapid spread of MPox Clade I in the Democratic Republic of the Congo has happened mostly through sexual contact within densely...

TCR-peptide-HLA ternary structures define molecular mechanisms of TCR cross-reactivity toward natural influenza variants.

Each time a man stands up for an ideal, or acts to improve the lot of others, or strikes out against injustice, he sends forth a tiny ripple of hope.Robert F. Kennedy, Senior

As horrific as it is that the Trump/Musk Administration is purging data from federal websites, it's good to know that the Internet Archive has been archiving much of it. However, in addition to the Ar...

The CDC said Thursday that the mutations, detected in a sample taken from a Louisiana patient, may help bind the virus to the upper airways in people.

The seasonal influenza vaccine contains strains of viruses from distinct subtypes that are grown independently and then combined. However, most individuals exhibit a more robust response to one of the...

A drug with a novel mechanism protects people against the AIDS virus for 6 months. It could speed the end of the epidemic—if those who need it most get access

Placide Mbala is part of Nature’s 10, a list of people who shaped science in 2024.

Some scientists examining mutations found in H5N1 viruses fear major outbreak is imminent but others says pathogen remains unpredictable

The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...

Associate Professor/Professor of Infection and/or Immunity in the Department of Pathology at the University of Cambridge.

Explaining the evolution of mpox, formerly monkeypox, and how it affects the body

Background Early in the coronavirus disease 2019 (COVID-19) pandemic, Sunda pangolins (Manis javanica) involved in the illegal wildlife trade in mainland China were identified as hosts of severe acute...

Bruton’s tyrosine kinase (BTK) is expressed in immune cells and microglia, where its role remains poorly understood. Here, the authors show that BTK modulates microglial neuroinflammatory pathways rel...