Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs) that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived IL-13 supports AF function...

Cancer immunotherapy benefits from antibody-lectin chimeras that block glyco-immune checkpoints.

Two scientists who are fast friends, one Nigerian and one American, have won the MacArthur Foundation's 100&Change competition for their network to catch the next disease with pandemic potential.

Building foundation simulation models for drug discovery

MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.

I’d like to take this opportunity to rebrand our lab's prior research as creating AI Virtual Cells! 🎉 😅 Like many others released lately, ours are mostly one-trick ponies, but we have a stable ...

Quick, but useful

Findings help decipher mechanisms through which ‘forever chemicals’ cause disease, aiding in treating health problems

YouTube video by Anne Carpenter

Generate simple pharmacophore models from RDKit. Contribute to tlint101/pharmacophore-toolkit development by creating an account on GitHub.

BRD4 functions as an intracellular pH sensor through a conserved histidine-rich intrinsically disordered region. Inflammation-associated acidification triggers a pH-dependent switch in transcriptional...

Are multi-modal molecular foundation models learning transferable representations across biology and chemistry?

Molecular filter is important for removing unwanted molecules from huge amout of comound dataset. And there are lots of filters are available in these days. For example, PAINS, Role of 5, Role of CNS etc... These filters are publically available but it's difficult to use from one platform. However datamol, medchem package can support lots of compound filters! You can read documentation of datamol from following URL.

Machine-learned interatomic potentials have transformed computational research in the physical sciences. Recent atomistic `foundation' models have changed the field yet again: trained on many differen...

Rigorous study design and analytical standards are required to generate reliable findings in healthcare from artificial intelligence (AI) research. On…

This time with Morgan fingeprint bits

Abstract . Comparing and searching protein structures independent of primary sequence has proved useful for remote homology detection, function annotation,

The European Research Council (ERC) decision to increase its support for leading researchers moving to Europe has today been formally adopted. On top of its standard grants, the ERC offers additional ...

I will never call myself an expert for to do so would be to take the first step down a very slippery slope.  It is important to remember th...