This study introduces MALVINA, a deep-learning platform that measures bacterial invasion and DNA damage in individual human cells, revealing how bacterial interactions and commonly used drugs reshape ...

This study shows that only those dual-targeting antibiotics limit resistance in Gram-negative pathogens that also target the membrane of the bacteria. This mechanism provides a basis for designing future antibiotics with reduced resistance potential.

The effect of new viral mutations on T cell responses remains unclear. Here, Balogh et al. show that most new mutations in SARS-CoV-2 are C > U, a bias that leads to an enhanced T cell re...

A study published in Nature Communications has revealed novel insights into bacterial resistance and offers a promising strategy for developing antibiotics that minimize the evolution of resistance.

This study shows that only those dual-targeting antibiotics limit resistance in Gram-negative pathogens that also target the membrane of the bacteria. This mechanism provides a basis for designing fut...

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics.

An extensive experimental analysis of resistance to antibiotics in development or introduced post-2017 in ESKAPE bacteria reveals the dynamics of resistance acquisition, mutational targets and the pre...

An extensive experimental analysis of resistance to antibiotics in development or introduced post-2017 in ESKAPE bacteria reveals the dynamics of resistance acquisition, mutational targets and the pre...

Antibiotic candidates induce multidrug resistance in Staphylococcus aureus without compromising bacterial viability.

Antibiotic candidates induce multidrug resistance in Staphylococcus aureus without compromising bacterial viability.

npj Antimicrobials and Resistance - The role of gene copy number variation in antimicrobial resistance in human fungal pathogens