Sign in

Rosie Jackson

@aramblingrosie.bsky.social
1.4K followers 339 following 36 posts

Principal Investigator in #neuroscience at the University of Dundee. Trying to understand #Alzheimer’s Disease. In a love/hate relationship with #ApoE. I love hiking, cycling, cooking, and brains (but not at the same time) 🚀🧪🧠👩‍🔬⛰️🚴🏻‍♀️👩‍🍳

PostsRepliesMedia
Rosie Jackson @aramblingrosie.bsky.social · 27/07/2026
If you’ve just completed an undergraduate degree and are interested in converting to a career in neuroscience, we still have places for 2026/27 on the Applied Neuroscience MSc programme at the University of Dundee, a one-year course with a summer research project. Find out more: uod.ac.uk/app-neuro
uod.ac.uk
Applied Neuroscience MSc
Get an advanced understanding of the brain and nervous system. Learn how to use it to solve real-world research problems and uncover new neuroscience knowledge
044
Reposted by Rosie Jackson
#NeuroDegeneration preprints @prepub-neurodegen.bsky.social · 13/05/2026
APOE Isoform-Dependent Self-Association Measured by a Split-Luciferase Complementation Assay: Differential Effects of Disease-Risk and Protective Variants #NeuroDegeneration 🧪🧠 www.medrxiv.org/content/10.64898/20…
001
Reposted by Rosie Jackson
Mike Greicius @mikegreicius.bsky.social · 12/05/2026
🧪 #neuroskyence #Alzheimer's #Alzheimer www.medrxiv.org/content/10.6... New paper describing the AD association of two rare APOE variants seen in admixed Native American ancestry (AMR) individuals. Small sample sizes, but consistent results across 2 cohorts. R189C 3x ⬆️ risk and W276C 3x ⬇️risk.
Forest plots for two rare APOE variants showing 3-fold increased risk for Alzheimer's in R189C carriers and 3-fold decreased risk for W276C
033
Rosie Jackson @aramblingrosie.bsky.social · 13/05/2026
Very excited to announce not one but TWO preprints from the lab in collaboration with Yann Le Guen. These papers came out of a wonderful collaboration and together tell a really satisfying story about APOE biology and Alzheimer's disease risk.
medrxiv.org
Association of Rare APOE Missense Variants R189C and W276C With Risk of Alzheimer Disease
Rare APOE missense variants in admixed populations can clarify mechanisms of Alzheimer disease (AD) risk beyond ε2 and ε4. We analyzed APOE coding variation in the Alzheimer disease Sequencing Project...
230
Reposted by Rosie Jackson
Catherine Hall @cathnaledi.bsky.social · 27/11/2025
I'm hiring! Come and work with me at UCL to try and understand how the brain's blood vessels go wrong and promote dementia: www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
1910
Rosie Jackson @aramblingrosie.bsky.social · 26/11/2025
Good morning from a stunnng sunrise over the Tay.
020
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 09/09/2025
Postdoctoral Researcher Vacancy in Structural or Chemical Biology at CeTPD, University of Dundee. Focus on molecular glue discovery in MND and FTD. Closing date: 6th October www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Research Assistant: Protein Degradation
Postdoctoral Researcher Vacancy in Structural or Chemical Biology at CeTPD, University of Dundee. Focus on molecular glue discovery in MND and FTD.
011
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 23/07/2025
Postdoc Research Assistant in Dr Arpan Mehta’s lab at University of Dundee, using CRISPR screens in iPSC-derived motor neurons to study ALS mechanisms. Closing date: 4th August www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Research Assistant: Investigating C9ORF72
Postdoc Research Assistant in Dr Arpan Mehta’s lab at University of Dundee, using CRISPR screens in iPSC-derived motor neurons to study ALS mechanisms.
076
Rosie Jackson @aramblingrosie.bsky.social · 22/07/2025
A nice productive morning for me then…
040
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 21/06/2025
Join Dr Arpan Mehta's lab at MRC PPU, Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons. Closing date: 18th July www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Research Assistant: Mechanisms of the C9ORF72
Join Dr Arpan Mehta's lab at MRC PPU, University of Dundee, for a 12-month postdoc using CRISPR screens to explore ALS in iPSC-derived motor neurons.
055
Reposted by Rosie Jackson
Claire Durrant @clairedurrant1.bsky.social · 30/04/2025
So excited to see our work finally out today in Nature Communications! Brilliant summary by co-first author @sorayam.bsky.social below!
2214
Reposted by Rosie Jackson
Tara Spires-Jones 🌈🔬 @tspiresjones.bsky.social · 30/04/2025
Fantastic to see this work from @clairedurrant1.bsky.social group out in print! Important results using living human brain tissue to study Alzheimer’s disease www.nature.com/articles/s41...
nature.com
Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures - Nature Communications
Understanding synapse loss in Alzheimer’s disease has been hampered by a lack of human model systems. Here, the authors show that manipulation of physiological or pathological Aβ has differing effects...
03711
Rosie Jackson @aramblingrosie.bsky.social · 24/04/2025
Always good to head back to st Andrews to chat with undergrads about neuroscience!
010
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 07/04/2025
Dr David Koss @davidkoss.bsky.social at University of Dundee is seeking a Postdoctoral Research Assistant to work on novel nuclear alpha-synuclein (aSyn) pathology and elevated DNA damage in Dementia with Lewy bodies. Closing date: 29th April www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
dementiaresearcher.nihr.ac.uk
Postdoc Research Assistant: DNA damage in LBD
Dr David Koss at University of Dundee is seeking a Postdoctoral Research Assistant to work on novel nuclear alpha-synuclein (aSyn) pathology and elevated DNA damage in Dementia with Lewy bodies
076
Rosie Jackson @aramblingrosie.bsky.social · 18/03/2025
We love ApoE!! Had a blast at the AAIC #APOE conference. Two whole days full of great talks, fab posters and wonderful chat with 250 of my fellow ApoE aficionados!
060
Rosie Jackson @aramblingrosie.bsky.social · 08/03/2025
In Edinburgh and just over heard a lad say to his friend that if Scotland loses today he’s going to piss on all the daffodils he can find. Stay classy Scotland. #sports!
110
Reposted by Rosie Jackson
Kira Shaw @kirasha.bsky.social · 07/03/2025
I am excited to have been awarded a Wellcome Trust CDA fellowship to study whether menopause enhances AD risk by exacerbating vascular dysfunction. I will be starting my lab in Manchester in January 2026, and would love to connect with other researchers interested in sex differences and AD 🧠🩸 🔬.
6193
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 06/03/2025
Dr @aramblingrosie.bsky.social at University of Dundee is seeking x2 #PhD Students to Investigate the effects of Rare ApoE variants on protein function & structure + the Impact of ApoE source and isoform on Neuroinflammation - Closing date: 31 March www.dementiaresearcher.nihr.ac.uk/find/jobs/?f...
dementiaresearcher.nihr.ac.uk
Jobs in Dementia Research
Find all the latest jobs in dementia research, in the UK and across the world. Working in all areas of discovery from fundamental science, clinical research, care and social sciences.
053
Rosie Jackson @aramblingrosie.bsky.social · 05/03/2025
Now is the moment!! If you'd like to come and do a PhD with me in sunny Dundee then I have not 1 but 2 funded PhD positions in my lab looking at #ApoE. Please reach out with any questions! Come do science with us, it'll be fun! www.dundee.ac.uk/phds/opportu... www.dundee.ac.uk/phds/opportu...
dundee.ac.uk
Investigating the impact of ApoE source and isoform on Neuroinflammation | University of Dundee, UK
A PhD project at the University of Dundee
0915
Rosie Jackson @aramblingrosie.bsky.social · 24/02/2025
#ARUK2025 here I come!
010
Rosie Jackson @aramblingrosie.bsky.social · 17/02/2025
Come and talk about mental health with us Wednesday at noon GMT! Your mental health is so so important and we all have one; it may be great, it may need nurtured, but the more we talk about it the more we understand it. I can't promise you any answers but hopefully you'll learn you're not alone!
022
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 02/02/2025
The last of our new first time contributors is Athina Grigoriou, from the Koss Lab at University of Dundee. Working to identify a reciprocal relationship between DNA damage and neurodegeneration, specifically in synucleiopathies. www.dementiaresearcher.nihr.ac.uk/profile-athi...
dementiaresearcher.nihr.ac.uk
Profile – Athina Grigoriou, University of Dundee - DEMENTIA RESEARCHER
Athina Grigoriou, PhD Student at the University of Dundee working to identify a reciprocal relationship between DNA damage and neurodegeneration, specifically in synucleiopathies
062
Rosie Jackson @aramblingrosie.bsky.social · 30/01/2025
That feeling you get when you read a study that was similar (but crucially different) to yours and saw a similar result is such an amazing feeling.
140
Rosie Jackson @aramblingrosie.bsky.social · 29/11/2024
Absolutely crucial paper showing that fixation time is important for RNAscope! We also saw this when setting up our work and I only wish a paper like this had existed at the time so we knew where and how to focus our efforts!!!
130
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 28/11/2024
If you missed this weeks webinar with tips on 'peer reviewing your first paper' you can watch the recording here: communities.dementiaresearcher.nihr.ac.uk/c/events/pee...
communities.dementiaresearcher.nihr.ac.uk
Dementia Researcher Salon - Peer Reviewing your First Paper
Dementia Researcher Salon - Peer Reviewing your First Paper
0106
Rosie Jackson @aramblingrosie.bsky.social · 27/11/2024
JOin us now to hear about how to review your first paper communities.dementiaresearcher.nihr.ac.uk/live/peer-re...
communities.dementiaresearcher.nihr.ac.uk
Dementia Researcher Communities
Login to Dementia Researcher Communities community via email or SSO today.
020
Rosie Jackson @aramblingrosie.bsky.social · 21/11/2024
My first Dundee #cellfie!!! They’re not much but they’re mine! Hoping they survived their trip across the pond.
050
Reposted by Rosie Jackson
Cathy Abbott @cathyabbott.bsky.social · 21/11/2024
The BNA scholars programme is now open for applications - this is a great scheme, instigated by @landreae.bsky.social (I can't tag the BNA as they aren't here yet I don't think) www.bna.org.uk/mediacentre/...
bna.org.uk
Applications welcome for 2025 entry to the BNA Scholars Programme | Media | The British Neuroscience Association
01412
Reposted by Rosie Jackson
adam grieve @adamgrieve.bsky.social · 15/11/2024
Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c
07179
Rosie Jackson @aramblingrosie.bsky.social · 20/11/2024
One week left to apply for this job!! I'm looking for a research tech to come and work on Alzheimers and ApoE! If you love cell culture, astrocytes, APOE or just fun science with fun people then come do science with us in beautiful Dundee! tinyurl.com/a33kjn49 Seriously the sunsets are on point!
Sunset over the tay bridge from The school of life sciences building in dundee
02018
Rosie Jackson @aramblingrosie.bsky.social · 18/11/2024
About to give my first taught lecture! Wish me luck BlueSky!
2200
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 13/11/2024
University of Oxford is seeking a Postdoctoral Research Scientist to join Dr. Becky Carlyle's lab working on membrane protein enrichment and preparation for mass-spectrometry analysis. Closing date: 21st November. www.dementiaresearcher.nihr.ac.uk/job/postdoct...
dementiaresearcher.nihr.ac.uk
Postdoctoral Research Scientist - DEMENTIA RESEARCHER
University of Oxford is seeking a Postdoctoral Research Scientist to join Dr. Becky Carlyle's lab working on membrane protein enrichment and preparation for mass-spectrometry analysis.
032
Rosie Jackson @aramblingrosie.bsky.social · 14/11/2024
What a lovely view from the top floor of the building today!!! #sunset
140
Reposted by Rosie Jackson
Sarah Cohen @cohenlaboratory.bsky.social · 12/11/2024
Any of my #APOE buddies here yet? Abstract submissions are open for AAIC Advancements: APOE and #Lipid Biology, March 17-18, 2025 in Miami www.alz.org/apoe/overvie...
alz.org
AAIC Advancements: APOE & Lipid Biology | alz.org
Neuroscience researchers should attend this Alzheimer's Association conference to discuss the role of APOE & lipid biology in neurodegenerative diseases.
3138
Reposted by Rosie Jackson
Amy Lloyd @amylloyd.bsky.social · 13/11/2024
My latest paper, deep proteomic analysis of mouse and human microglia: www.cell.com/cell-reports...
cell.com
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems
Lloyd et al. generated a comprehensive microglia proteome database, identifying over 11,000 proteins. Fundamental differences between ex vivo and in vitro microglia associated with protein synthesis, ...
39828
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 13/11/2024
Dr Maura Malpetti at University of Cambridge is looking for a Research Assistant / Research Associate to investigate inflammation in frontotemporal dementia (this is a second position). Closing date: 8th December www.dementiaresearcher.nihr.ac.uk/job/research...
dementiaresearcher.nihr.ac.uk
Research Assistant / Associate: Inflammation in frontotemporal dementia
Dr Maura Malpetti at University of Cambridge is looking for a Research Assistant / Research Associate to investigate inflammation in frontotemporal dementia.
045
Reposted by Rosie Jackson
Dementia Researcher @dementiaresearcher.bsky.social · 13/11/2024
Dr Maura Malpetti at University of Cambridge is looking for a Post-Doctoral Research Associate to investigate inflammation in frontotemporal dementia. Closing date: 8th December. www.dementiaresearcher.nihr.ac.uk/job/research...
dementiaresearcher.nihr.ac.uk
Research Associate: Inflammation in frontotemporal dementia
Dr Maura Malpetti at University of Cambridge is looking for a Post-Doctoral Research Associate to investigate inflammation in frontotemporal dementia.
033
Rosie Jackson @aramblingrosie.bsky.social · 12/11/2024
Autumn colors
160
Reposted by Rosie Jackson
RSPB @rspb.bsky.social · 11/11/2024
No words, just Red Squirrel energy. #MondayMotivation
This Red Squirrel strikes a playful pose mid stride on a tree branch, its fluffy tail arched behind it and one paw confidently raised as though giving a bold wave. With its tufted ears alert and eyes wide, the squirrel looks full of energy, its reddish-brown fur standing out against the bark. A perfect snapshot of woodland mischief and charm.
1048266430
Rosie Jackson @aramblingrosie.bsky.social · 11/11/2024
Job Alert!!! I'm looking for a research tech to come and work on Alzheimers and ApoE! If you love cell culture, astrocytes, APOE or just fun science with fun people then check out the job posting below. Come do science with us in beautiful Dundee! tinyurl.com/a33kjn49
020
Rosie Jackson @aramblingrosie.bsky.social · 11/11/2024
Hello world.
050