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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc

@christosargyrop.bsky.social
10K followers 2.5K following 4.8K posts

Division Chief, Nephrology UNMHSC (im)personal views & account #zerokale Firm believer : caveat emptor & stupidity is immoral Random thoughts about #nephrology #stats #bioinformatics #perl #HPC #nanopore #RNAseq #covid19 #amateurcoding #ButlerianJihad

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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 5h
I bought these drives 1.5 - 2 years ago, inflation is real
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
weaselproof @weaselproof.bsky.social · 13h
Web devs learned 15 years ago that there is no such thing as anonymized data. Now the AI bros gonna relearn that about training data. Or more properly, go to absurd lengths to avoid learning it
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
K. Thor Jensen @kthorjensen.bsky.social · 14h
chat is this good
best_of_web 1d
A customer just tried to use an employee discount code that ChatGPT gave her. I work at a high-end clothing store and clocked in to my manager telling me about the most unhinged interaction from yesterday. A woman walked in asking if she could use a 40% off code she got online. We don't have any sales running, so my manager looks at the screen and realizes ChatGPT straight up handed this woman a real employee's internal ID number.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 11h
Age verification coming to NM soon?
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 12h
We officially closed down the Zeus study today. I would like to thank the sponsor @novonordisk.bsky.social for the excellent collaboration and their very professional research staff who worked with us on this trial.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 18h
If Intel had not axed Optane it would have made a killing now with the DRAM price crisis. It would have needed a PCI4.0 or PCI5.0 interface ofc but things like swapping contexts/storing and restoring to model memory and swapping of models would have made batch local inference possible
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 01/10/2026
Shedding season - bless your heart
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 30/09/2026
The AI economics math are not mathing (longer version of a short tweet/post/toot) christosargyropoulos.substack.com/p/the-ai-mat...
christosargyropoulos.substack.com
The AI math are not mathing
Why you should ignore the cheerleading botlickers
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 30/09/2026
To see why the AI math are not matching, ask any cheerleading botlicker about what the end game should look like. They will tell you subscriptions (which they value at $100/month). That is ~450B a year if we everyone gets one which is the size of the US home improvement industry.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 28/09/2026
#FAFO #WinterIsComing #Insurance #HealthcareExpenditures
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 28/09/2026
From an interaction at X. Northern Ireland remoces the requirement for covid19 testing of symptomatic staff working in clinical areas including those with immunocompromised patients. www.publichealth.hscni.net/covid-19-cor... Someone had a sense of humor because it was released on Enola Gay day
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 26/09/2026
To all the Daves and Davinas out there www.reddit.com/r/managers/s...
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 24/09/2026
There is wisdom in buying 2 Hirsch/yubi keys at the same time. Having FA the purchase part, I have just FO the wisdom
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
𝕁, Atheoretic Text Monster™ @checkwithscience.com · 23/09/2026
why don't any of these fucking things charge with USB-C? jumanjiwhatyearisit.gif
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 23/09/2026
One of the things that still to this day puzzle me is why statisticians don't deconstruct various AI tools to map them to existing constructs/models/methods of their trade. It would have become rather obvious that some (or even all) of the AI are rebranded statistical models, which in turn would
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 20/09/2026
This is going to be a long night, the chatbots need to be reminded frequently that #Rstats + #Perl > #Python #Bioinformatics #AI
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 19/09/2026
This is gonna be my response to our family piano teacher (I am the only one who is not taking lessons) when she suggests I take up lessons: let's wait after death.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Josh Krasnow @jmksnow.bsky.social · 19/09/2026
@christosargyrop.bsky.social says kale is just the thing
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 18/09/2026
This Progressive Techno Remix of Vivaldi is just wild music.youtube.com/watch?v=nvfO...
music.youtube.com
Your browser is deprecated. Please upgrade.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Grant Tosterud @granttosterud.bsky.social · 17/09/2026
Over the last three days, New Mexico has received the 2nd-highest volume of rainfall of any state in the country. An estimated 1.5 TRILLION gallons of rain have fallen across the state! #NMwx
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 16/09/2026
Topped up last week : 80.15 dollars for 15.875 gallons of the 91 octane gas ie around 5.09 gallons to the dollar. Seems price went up slightly today 🥳😎
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 15/09/2026
The #covid19 azelastine prophylqxis trial needs replication, but until then, here is a mechanistic analysis
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 14/09/2026
In other news, Trump calls out the FUD BS of the AI trio. What are time to be alive! "Trump says 'very negative forces' raising exaggerated concerns over AI" www.reuters.com/world/europe...
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 13/09/2026
The companies that tell you their AI products will destroy the world often offer weekend discounts through GithubCopilot to encourage usage. They cannot compete on price with the ChineseModels, they are burning cash they can no longer secure from VC & their IPOs are doomed to flop. Put 2+2 together
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Frank Harrell @f2harrell.bsky.social · 23/08/2026
The gold standard for producing PDF documents (especially books and journal articles) has been LaTeX. @typst.app re-engineered the entire process in an incredibly elegant extensible way. On my MacOS LaTeX (TexLive) takes 9.1GB of disk space. Typst takes 43MB. Not a misprint.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 13/09/2026
Time to regulate GEMM and GEMV for safety in the name of #AI alignment. Anyone using #BLAS without a license especially if they are running models locally will go to Gitmo
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 12/09/2026
If I were to be a disruptive and dismissive asshole, I'd point out that the Navier Stokes solution is a gimmick to make the numpties lose $ on the AI IPO since all work in fluid mechanics that matters is done through numerical calculations. Solve cancer or go home
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Mark Chadbourn @chadbourn.bsky.social · 11/09/2026
Bad to worse.
chadbourn.substack.com
The Iran War Hits Crisis Point
Free access to the Red Sea has been lost
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 10/09/2026
The Venn diagram of Personalized Medicine/multiomica fundamentalists and AI jihadis is a cycle
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 09/09/2026
The ADA tries to coverup with a superficial report www.medpagetoday.com/publichealth... And previous coverage www.medpagetoday.com/special-repo... #ADAGate @amdiabetesassn.bsky.social
medpagetoday.com
ADA Says Its Investigation of Meeting Controversy Isn't Done Yet
Diabetes group changes its tune not long after announcing top-line review findings
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 10/09/2026
Just to be clear disallowing or capping publication costs in grants is not a bad idea. Some journals are asking for exorbitant fees, enough to fund a few months of a new post doc or pay for a big equipment or even the cost of a new experiment.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
public health guy @publichealthguy1.bsky.social · 10/09/2026
📈📈📈
Gas Station Price Sign Using Scientific Notation

the ONION
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Patrick De Haan @gasbuddyguy.bsky.social · 10/09/2026
MAXXED OUT at $9.999!! GasBuddy data showing 5 stations in California that have hit the limit and are selling diesel at the dispensers highest possible price: $9.999/gal
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 09/09/2026
The real scandal is that this is such a patchwork system of rules www.medpagetoday.com/publichealth... @christosargyrop.bsky.social ?
medpagetoday.com
Medicare Paid Nearly $400M for Organs Never Used for Enrollees
Most were used in non-covered transplants and some weren't used at all, OIG report finds
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 08/09/2026
We should probably do away with HIPAA as is and put the fines and long term imprisonment terms without parole on the people who use data they were not supposed to have.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Playboy @playboy.com · 07/09/2026
Men are "pheromone-maxxing," skipping showers before dates. Kelly Oxford weighs in on whether women really like this. The answer is no.
playboy.com
Please Don't Skip a Shower Before Your Date, Guys
Men are "pheromone-maxxing," skipping showers before dates. Kelly Oxford weighs in on whether women really like this.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Kieran Healy @kjhealy.co · 07/09/2026
Writing some scientific workflow slides for this week’s MPTC class.
Research workflow for those branches of the sciences where the important thing is to become famous.
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Source New Mexico @sourcenm.com · 07/09/2026
New Mexico officials on Sunday swiftly denounced Donald Trump's social media posts suggesting a new name for the state. buff.ly/23G8IUq
sourcenm.com
New Mexico officials reject Trump post proposing state name change • Source New Mexico
New Mexico Democratic elected officials pushed back at President Donald Trump's social media posts suggesting a name change for the state.
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NM Dept. of Memes @nmdeptofmemes.bsky.social · 06/09/2026
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 06/09/2026
It is happening 🤣🤣🤣 (That means we have to update addresses on credit cards, bank accounts , IRS , SSA etc)
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
DioCyni @madgreek.bsky.social · 06/09/2026
Randomly posted by Aquaman and Mermaids Inc.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 06/09/2026
I was monitoring my #KimiK3 sessions in the morning by looking at the thinking trace, when I saw this unconnected to anything else really: "Bribing the hamster".
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 05/09/2026
Very pleased with Kimi K.3 which I took for a ride today via #GithubCopilot. Good questions, solid plans, efficient, token frugal implementations in a multilanguage project with multiple branches: C, #Python, #Perl, #rstats #make. It handled documentation needs too. #KimiK3 FTW
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 05/09/2026
Simply brilliant (from "The Volatile Mermaid" at Bluesky)
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
The Volatile Mermaid @ohnoshetwitnt.bsky.social · 05/09/2026
When old SVU episodes don’t hold up in modern times.
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 05/09/2026
Possibly relevant onlinelibrary.wiley.com/doi/abs/10.1...
onlinelibrary.wiley.com
Essential Role of T Cells in the Postexposure Prophylaxis of Rabies in Mice
Athymic nude mice injected intramuscularly with a street strain of rabies virus were not protected against rabies by postexposure administration of beta-propiolactone-inactivated rabies vaccine. In…
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Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc @christosargyrop.bsky.social · 05/09/2026
I never followed the genetic data on LP(a) but apparently there is so much moaning that it betrayed us (or rather the cardiologists and 2 pharmas) so I have got to ask: were the genetic data , garbage polygenic risc scores, mendelian randomization, or something equally worthless?
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Lars Mølgaard Saxhaug @load-dependent.eurosky.social · 03/09/2026
This something only a human mind can do. Brilliance!
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Greenglish 🇺🇦 @kolyk.bsky.social · 03/09/2026
Αν κοπεί το ρεύμα δεν με σώζει το AC 😬
theguardian.com
Minister tells Brits to stock up on days of supplies after ‘supersize’ El Niño warning
Exclusive: UK government plans campaign urging citizens to prepare for national emergencies
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Reposted by Christos Argyropoulos MD, PhD, FASN 🇺🇸 0kale/acc
Unapologetic Lee 🇨🇦 @ogcanada.bsky.social · 03/09/2026
When Chinese models are significantly cheaper, American AI will never compete.
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