Changes in guidance and science seem to have little impact on millions of devastated lives. It’s a social crisis playing out behind closed doors, says Guardian columnist George Monbiot

Multiple studies have found an increased response of the hormone prolactin to the drug buspironeContinue readingIncreased prolactin response to buspirone

The story of functional neurological disorder is beginning to turn a corner.

Now, when exposed to the simulated hypoxic conditions, the Lac/tCr ratio increases less than healthy controls, this could mean there is a lesser capacity for additional compensatory glycolysis to be g...

Background: There is a critical need for interventions for long COVID. Our aim was to conduct a systematic review on the efficacy and safety of different interventions in patients with long COVID. Met...

By matching DNA results with gene expression databases researchers can determine the tissues and cellContinue readingCell and tissue enrichment in ME/CFS

Insider accounts reveal the scale of the health secretary's ambitions to curb childhood immunizations and unearth a link between vaccines and autism.

Background Hyperbaric oxygen therapy (HBOT) has been proposed as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but evidence remains limited. This study evaluated its cli...

Long COVID has often been suspected to involve ongoing inflammation in the brain caused by SARS-CoV-2 infection. Scientists have explored this theory as a possible explanation for symptoms such as fatigue, brain fog, anxiety, and depression. However, direct proof has remained limited. To investigate the issue more closely, researchers at the University of Turku in Finland used advanced brain imaging techniques to examine people with long COVID who continued to experience symptoms long after infection. "We did not observe evidence of widespread brain inflammation in patients with long COVID when compared to healthy controls," says Professor of Neuroimmunology and InFLAMES Research Flagship group leader Laura Airas, who led the study. Comparing Long COVID Patients With Healthy Volunteers and MS Patients The study included 14 people with long COVID, 11 healthy participants, and 13 individuals with multiple sclerosis (MS), a neurological disease known to involve inflammation in the brain. All participants underwent PET scans designed to detect neuroinflammation, along with magnetic resonance imaging (MRI) scans to evaluate brain structure and changes in white matter. Researchers also analyzed blood samples for biological markers associated with damage to neurons and supporting brain cells. Compared with patients who had MS, the long COVID group...

The UK government has given nearly £5 million to fund full sequencing of the DNA of 6,000 people with ME using the best available technology. This will help scientists home in on what is really dri…

Naltrexone is prescribed off-label at low doses, typically 0.5–6.0 mg, for a variety of therapeutic indications. This review evaluates the clinical evidence for low-dose naltrexone (LDN). A literature...