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ME/CFS Science @mecfsscience.org · 15/05/2026

1) 🇪🇸 A new Spanish study measured autoantibodies against adrenergic and muscarinic receptors in 59 patients with ME/CFS, 96 Long Covid and 36 healthy controls. The results show a large overlap, questioning whether these antibodies are involved in ME/CFS pathology.

Graph showing large overlap in adrenergic and muscarinic autoantibodies between ME/CFS patients, Long Covid patients, and healthy controls.

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Henrik Scheel @langemand.bsky.social · 15/05/2026

A new study using Fukuda criteria? I suspect intentional non-findings.

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Simon McGrath @simonmcg.bsky.social · 15/05/2026

I'm encouraged that we are seeing most studies on specific areas, especially when it's some separate groups. (We also had the null trial results.) This is the only way to make progress. Limitations of this study noted.

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ME/CFS Science @mecfsscience.org · 15/05/2026

2) ME/CFS patients did have slightly higher B2 adrenergic antibodies - similar to a previous study by Scheibenbogen's group - but this was likely due to a couple of outliers at the top. Most of the ME/CFS patients and controls were in a similar range with lots of variation.

Graph showing autoantibodies against B2 adrenergic receptors in ME/CFS, Long Covid and healthy controls.

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Protein and Veg and Fasting @mccheapo.bsky.social · 15/05/2026

They should be measuring resting RER. #mecfs

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