For people interested in details of this study on brain scans and hypoxia in ME/CFS.
One of the authors wrote a very thoughtful reply to comments about the study on the S4ME forum. Read the discussion here:
s4me.info/threads/expe...
s4me.info
Preprint - Experimental hypoxia to probe neuro-metabolic and vascular dysregulation in ME/CFS: a multimodal proof-of-concept MRI study, 2026, Bader et al.
Now, when exposed to the simulated hypoxic conditions, the Lac/tCr ratio increases less than healthy controls, this could mean there is a lesser capacity for additional compensatory glycolysis to be g...
@mecfsscience.org1) 🇦🇹 Interesting study that tested brain blood flow and metabolites under experimentally induced hypoxia (they gave ME/CFS patients less oxygen while lying under the MRI scanner).
The idea is that this might reveal brain differences during a stressor.
