iiinova — where your digital self keeps evolving

Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/03/2026

Finally, FINEONE shows Finerenone reduces albuminuria in T1DM www.nejm.org/doi/full/10.... @nejm.org #NephSKy

figure of albuminuria reduction with finerenone

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Anand Vaidya @anandvaidya17.bsky.social · 07/09/2025

To accompany the new ACC/AHA BP guidelines, a practical guide on how to test for Primary Aldosteronism: now recommended for most people with hypertension. www.jacc.org/doi/10.1016/...

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

thecurbsiders.bsky.social @thecurbsiders.bsky.social · 25/02/2026

Primary Aldosteronism! ♥️ Did you know up to 50% of people with hypertension might have inappropriate aldosterone production? For the full episode #515 with expert guest @anandvaidya17.bsky.social visit thecurbsiders.com

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

JACC Journals @jaccjournals.bsky.social · 19/02/2026

🆕 ACC/AHA/Multisociety Guideline for the Evaluation & Management of Acute PE in Adults is a de novo document offering comprehensive, evidence‑based recommendations for the evaluation, management & follow‑up of adults with acute PE. bit.ly/4aE5gmi #JACC #CardioSky #ClinicalGuidelines

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

JACC Journals @jaccjournals.bsky.social · 23/02/2026

2026 ACC/AHA/Multisociety guideline on acute pulmonary embolism highlights practice-changing recommendations for the evaluation & management of acute PE in adults. Explore the Guideline-at-a-Glance in #JACC to accelerate adoption in practice: bit.ly/4rwGoEd #ClinicalGuidelines #CardioSky

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

NEJM.org @nejm.org · 22/02/2026

Ischemic stroke, defined as a central nervous system injury caused by loss of blood flow, is most often due to arterial thromboembolism. Evaluation should include relevant blood tests and cardiovascular and cardiac investigations (seen in table). Learn more: nej.md/3OFpJ2C

Table 2. Common Diagnostic Studies to Aid in Secondary Stroke Prevention.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Emily Moin @emilymoin.com · 08/12/2025

Feels like a good day to shout into the ether that when a service is free, you are the product.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

NEJM.org @nejm.org · 09/11/2025

In a meta-analysis of 17,801 patients with myocardial infarction and preserved LVEF (≥50%), beta-blockers did not reduce death, MI, or heart failure over a median 3.6 years of follow-up. Full results: nej.md/43U5Ppo #AHA25

Kaplan–Meier curves of the cumulative incidence of death from any cause, myocardial infarction, or heart failure (the composite primary end point).

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

NEJM.org @nejm.org · 08/10/2025

In rural South Africa, home-based hypertension care — delivered by community health workers and supported by remote nurses — led to a lower mean systolic blood pressure than clinic-based care. Full IMPACT-BP trial results and Research Summary: nej.md/4lHJ4ek #MedSky #CardioSky

The New England Journal of Medicine
Home-Based Care for Hypertension in Rural South Africa
A Research Summary based on Siedner MJ et al. | 10.1056/NEJMoa2509958 | Published on September 1, 2025

Visual representations of the patients in the trial and the treatments they were assigned.

Read the full Research Summary at NEJM.org.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Oded Rechavi @odedrechavi.bsky.social · 07/10/2025

Fwd: Fwd: “I hope this email finds you well”

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

American College of Cardiology @accintouch.bsky.social · 29/09/2025

🩺 Knowledge is power. 🫀 On this #WorldHeartDay, empower your patients to take control of their heart health with #CardioSmart tools like this high #bloodpressure infographic. 🔗 Explore more: bit.ly/46I6k6F #DontMissABeat #WorldHeartDay

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

John Giacona, PhD, PA-C @giaconajohn.bsky.social · 29/09/2025

Subclinical primary aldosteronism is an under-recognized driver of cardiovascular risk. Could it be a new target for CV prevention? Read our Circulation editorial —>

ahajournals.org

Subclinical Primary Aldosteronism: A Potential New Target in Cardiovascular Prevention? | Circulation

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

JAMA @jama.com · 28/09/2025

Superficial vein thrombosis (SuVT) is characterized by thrombus in the superficial veins, typically in the lower or upper extremities. This Review summarizes the diagnosis and treatment of SuVT. ja.ma/46CnGlh

Diagram from JAMA, Sept 15, 2025, titled "Superficial Vein Thrombosis: A Review." It shows common sites and pathophysiology of SuVT in upper and lower extremities, detailing vein names, thrombus formation, inflammation, and impeded blood flow.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Goodishintent @omnintensivist.bsky.social · 28/09/2025

*At grandson's birthday* Me: ...so that's why you should get your kid enrolled in swim lessons. Son: MOM ARE YOU TELLING DROWNING STORIES TO THE GUESTS AT MY SON'S BIRTHDAY PARTY? Me: Son: Me: I can change.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

😱 Spooky SpectreKILLoquy 🔪 🩸 @caulimovirus.bsky.social · 19/09/2025

CDC to recommend looking only one way before crossing street

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Journal of Hospital Medicine @jhospmedicine.bsky.social · 25/09/2025

#TWDFNR: Primary/essential hypertension? Or...primary aldosteronism? JHM Digital Media Fellow Eric Burnett discusses why we might not be screening our patients with elevated blood pressures, and why we should! bit.ly/4pymLv7 #VisualAbstract: Sophie Sun 📹: @Eric

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

JACC Journals @jaccjournals.bsky.social · 25/09/2025

📢 New in #JACC: ACC/AHA methodology statements on: 🔹 Core Principles & Development 🔹 Cost/Value (update) 🔹 FDA Processes Together with Circulation, they provide the framework to keep guidelines rigorous, transparent & responsive. 🔗 Explore the statements: bit.ly/3IE4EDc #CardioSky #MedSky

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

American College of Cardiology @accintouch.bsky.social · 24/09/2025

Early identification is 🔑 for FH. Use #CardioSmart’s FH infographic to explain types of FH & support patient conversations. To celebrate #FHAwarenessDay, CardioSmart is offering free handouts & posters for a limited ⏰. Learn more & order now ➡️ bit.ly/4gKKlRk #KnowFH #CardioSky #MedSky

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

American College of Cardiology @accintouch.bsky.social · 20/09/2025

Help your patients better understand #AFib with #CardioSmart’s Spanish infographic! 👇 CardioSmart offers infographics and decision aids in multiple languages to support patient–clinician conversations. Explore the resources: bit.ly/4pxad6Y #AFibAwarenessMonth #ACCLATAM #CardioSky #MedSky

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Joel Topf @kidneyboy.bsky.social · 19/09/2025

You say "happy birthday," I say "Another year older, another loss of 0.9 ml/min of eGFR"

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Joel Topf @kidneyboy.bsky.social · 13/09/2025

Some information (still not primary data, more like marketing speak) about the Apple Hypertension detection. >2,000 adults wore the watch ~12 hours/day for a month and took BID cuff BP; The watch was “as accurate as the cuff” for detecting signs of HTN what ever that is time.com/7316725/appl...

time.com

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

ACOG @acog.org · 22/09/2025

ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. bit.ly/47Wxc59

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

ASN Publications @asnpublications.bsky.social · 06/09/2025

New in #ASNJASN and at #Hypertension25: In a randomized, double-blind, placebo-controlled trial, Baxdrostat reduced systolic blood pressure in patients with CKD and uncontrolled hypertension. Read more about its safety and efficacy in patients with CKD here: kidney.pub/JASN0849

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

NEJM.org @nejm.org · 21/09/2025

In patients with localized colorectal cancer and PIK3CA hotspot mutations in exon 9 or 20, daily low-dose aspirin resulted in a significantly lower recurrence rate than placebo. Full ALASCCA phase 3 trial results and Research Summary: nej.md/4mpKXNp #MedSky #Oncology

The New England Journal of Medicine
Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer
A Research Summary based on Martling A et al. | 10.1056/NEJMoa2504650 | Published on September 18, 2025

Visual representations of the patients in the trial and the treatments they were assigned.

Read the full Research Summary at NEJM.org.

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Shematologist, MD @shematologist.medsky.social · 16/09/2025

It’s a beautiful day to go get vaccinated!

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T1h Next up – Secondary HTN. The guideline provides a thorough table including 15 causes of secondary HTN with indications for additional testing and diagnostic screening tests for each. #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T4g 7️⃣Pregnancy thresholds updated - Treat chronic HTN in pregnancy to <140/90 and acute severe HTN ≥160/110 within 30–60 min (COR I, LOE B-R). 📝Are you routinely consulted for hypertension in pregnancy? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T4e 5️⃣Primary aldosteronism screening – screen all adults with resistant HTN regardless of potassium level (COR I, LOE B-NR). Continue most antihypertensives except MRA before testing (COR I, LOE C-EO). 📝Is screening worthwhile or should we just be using MRAs earlier? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T4i 9️⃣Cognitive protection🧠 - treat to SBP <130 to prevent mild cognitive impairment/dementia (COR I, LOE B-R). 📝Do you think BP control has a significant role in dementia? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T3a 1️⃣3️⃣Terminology change – Hypertensive Urgency (BP > 180/120 without target organ damage) is now referred to as Severe HTN. No need for parenteral therapy, best to treat in the outpatient setting. 📝What’s in a name (renal, nephro, kidney)? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Dr Pallavi Prasad, MD, DNB ( Nephrology) @drpallaviprasad.bsky.social · 17/09/2025

Proposed mechanism in Nature #NephJC www.nature.com/articles/s41...

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T4b 2️⃣Risk-based treatment threshold – Use PREVENT 10-yr CVD risk ≥7.5% to guide drug initiation at ≥130/80; if risk <7.5%, try lifestyle first for 3–6 mo, treat if still ≥130/80 (COR I, LOE B-R). 📝How effective is lifestyle modification in your practice? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Dr Pallavi Prasad, MD, DNB ( Nephrology) @drpallaviprasad.bsky.social · 17/09/2025

Interesting study from 2019! #NephJC 8.9% of OSA have PA. Almost 70% of PA have OSA! www.ahajournals.org/doi/10.1161/...

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T4a 1️⃣BP categories unchanged - normal <120/80, elevated 120–129/<80, stage 1 130–139/80–89, stage 2 ≥140/90 (COR I, LOE B-NR). 📝You know we love to categorize things. Were you hoping for a change? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

9:39 So ACC/AHA hasn’t updated their guidelines since 2017. Let’s break down what’s different and new! Lots to discuss #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T2o To round out the discussion on HTN management: Renal Denervation (RDN) Class 2b (weak) recommendation for renal denervation in carefully selected patients with resistant HTN. Initial studies were promising, however in the end RDN only had modest effects (equivalent to adding 1 BP med) #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T2b It’s pretty much back to the basics for lifestyle (weight loss, exercise, limiting sodium and alcohol, and eating a potassium rich diet). There are a few newcomers though: ✔️Potassium-based salt substitutes (except in CKD, think SSaSS study) ✔️Meditation ✔️Breathing control #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T1g Following a HTN diagnosis, there is more to evaluate. Here’s the list: ➡️CBC ➡️Serum electrolytes ➡️SCr ➡️Lipid profile ➡️Glucose/A1C ➡️TSH ➡️Urinalysis ➡️UACR (Hooray!) ➡️ECG Are you already doing this? Are there other parameters you routinely monitor? #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Nephrology Journal Club @nephjc.bsky.social · 17/09/2025

T2n Studies have shown that even moderate weight loss (5-10%) can significantly lower BP. GLP-1 receptor agonists may be effective adjunctive therapy to lower BP when used for weight management in those with BMI ≥27 kg/m2 #NephJC

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Jordy Cohen @jordybc.bsky.social · 17/09/2025

Captures similar people From the AHA scientific statement on PREVENT: www.ahajournals.org/doi/10.1161/... #nephjc

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Eric Topol @erictopol.bsky.social · 27/05/2025

2 new studies on weight loss 1. Sustained reduction during midlife improved survival and reduced chronic diseases jamanetwork.com/journals/jam... 2. A randomized trial found patient-to-patient care was more effective than professional for weight loss and less CV risk jamanetwork.com/journals/jam...

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Amy G Dala, MD @amygdalamd.bsky.social · 17/05/2025

Babies don’t have sleep problems, we have problems with their sleep

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Dr Martha Gulati @drmarthagulati.bsky.social · 30/04/2025

The 2025 AHA/ACC Clinical Performance and Quality Measures for Patients With Chronic Coronary Disease: A Report of the @americanheart.bsky.social @accintouch.bsky.social Joint Committee on Performance Measures @ahajournals.bsky.social @smidtheart.bsky.social www.ahajournals.org/doi/10.1161/...

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Helen Hương Kilminster @hpillminster.pharmsky.app · 01/05/2025

Hypertension management and early HF detection (plus specific read coding for PCN DES) is a enormous focus this year for us in General Practice. Nuances regarding HTN in HF 🤔 This piqued my interest. Presentation executed phenomenally well #BSHMDT2025 #PharmSky #Cardiosky

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Henry Han @hancardiomd.bsky.social · 13/04/2025

#Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the #FINEARTS-HF trial onlinelibrary.wiley.com/doi/full/10.... @escardio.bsky.social #CardioSky @

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Shematologist, MD @shematologist.medsky.social · 10/04/2025

PSA: Your period should not 🩸last longer than 7 days 🩸interfere with your life 🩸happen more than monthly 🩸require product changes more than every 2 hours 🩸have clots larger than a quarter 🩸cause debilitating pain 🩸require double product coverage 🩸make you anemic

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Stephen P Juraschek, MD, PhD, FAHA, AHSCP-CHS @spjuraschek.bsky.social · 12/04/2025

Neat comparison of hypertension guidelines for CKD @nkf-professionals.bsky.social

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Stephen P Juraschek, MD, PhD, FAHA, AHSCP-CHS @spjuraschek.bsky.social · 12/04/2025

Aerobic exercise is so good for your blood pressure!!! @nkf-professionals.bsky.social

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Reposted by Carlos Nolasco, MD, FACP, AHSCP-CHS

Stephen P Juraschek, MD, PhD, FAHA, AHSCP-CHS @spjuraschek.bsky.social · 12/04/2025

Measure blood pressure well! @nkf-professionals.bsky.social

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