Sign in

John Giacona, PhD, PA-C

@giaconajohn.bsky.social
501 followers 728 following 17 posts

Assistant Professor | Hypertension Specialist UT Southwestern Medical Center

PostsRepliesMedia
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 15/03/2026
Congratulations to 2 lab members who have retired from our group. Yun Wang and Ms Carmen White. Thanks for their dedication to work and teaching of new generation of researchers @jesslin23.bsky.social @giaconajohn.bsky.social
022
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 28/02/2026
Excellent overview in The Washington Post on the systemic impact of sustained hypertension — from LVH to CKD and cognitive decline. Kudos to Drs. @drwanpen.bsky.social , John B, and @jordybc.bsky.social for evidence base insight. 🔗 www.washingtonpost.com/wellness/202... #Hypertension #Cardiology
washingtonpost.com
What high blood pressure does to your body
Hypertension can affect your mind, heart, eyes and more, often without causing any obvious symptoms at all.
086
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 18/02/2026
New analysis led by our PhD candidate @robynwei.bsky.social shows ⬇️ salt substitute use among US adults, Not good for BP. 🚫 real salt @giaconajohn.bsky.social @jesslin23.bsky.social @utswim.bsky.social @jongarinn.bsky.social ahajournals.org/doi/10.1161/...
094
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 21/01/2026
Our new paper @jesslin23.bsky.social showing low accuracy when eyeballing BP log and more importantly may lead to failure to start or ⬆️BP meds in HTN. Thanks 🙏all faculty&trainees for helping us @utswim.bsky.social www.ahajournals.org/doi/full/10.... @robynwei.bsky.social @giaconajohn.bsky.social
084
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 12/12/2025
Such a blast as always! But now I want a burrito 🌯
020
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 05/12/2025
Good HTN journal club today by @robynwei.bsky.social discuss effects of ultraprocessed food on cardiometabolic health @giaconajohn.bsky.social @hkkimphd.bsky.social Need to eat less UPF! www.nature.com/articles/s41...
143
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 03/10/2025
great HTN JC discussion today on BAXHTN study by Dr. Shawna Nesbitt joined by @dramitkhera.bsky.social @giaconajohn.bsky.social @utswim.bsky.social Interesting that baseline aldosterone in the trial was around 7.5 ng/dL by LCMS with baseline PRA is 1 ng/mlhr. This means that majority of pts have PA
071
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 03/10/2025
🏆 First time at Epic Cosmos Datathon—our team took 1st place! Grateful for the collaboration and hands on experience ! @drwanpen.bsky.social Excited to present tomorrow (Oct 3) at Pegasus Park Symposium on “Missed Opportunities: Screening for Primary Aldosteronism” #EpicCosmos #HTN
051
Reposted by John Giacona, PhD, PA-C
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 02/10/2025
Excellent commmentary from @giaconajohn.bsky.social and @drwanpen.bsky.social
161
Reposted by John Giacona, PhD, PA-C
American Journal of Hypertension @amjhypertension.bsky.social · 02/10/2025
Comparing Management strategies for Primary Aldosteronism: Is it 🍎 versus 🍊 ? Commentary academic.oup.com/ajh/article-... based on academic.oup.com/ajh/article-... #Hypertension #Aldosteronism
academic.oup.com
Optimal Treatment of Primary Aldosteronism: Can We Compare Apples to Oranges?
Primary aldosteronism (PA) is an endocrine disorder characterized by inappropriate and excessive aldosterone production.1 PA is a prevalent cause of elevat
2104
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 29/09/2025
Subclinical primary aldosteronism is an under-recognized driver of cardiovascular risk. Could it be a new target for CV prevention? Read our Circulation editorial —>
ahajournals.org
Subclinical Primary Aldosteronism: A Potential New Target in Cardiovascular Prevention? | Circulation
087
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 23/09/2025
Our new study that links high Phosphate diet found in processed food and anxiety behavior and alternation of genes involved in mood regulation in mice. That may explain why we don't feel good after a whopper or a big Mac @hkkimphd.bsky.social @utswim.bsky.social sciencedirect.com/science/arti...
071
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 12/09/2025
great HTN journal club discussing GWAS in primary aldosteronism by @jdmosley-moses.bsky.social @giaconajohn.bsky.social www.ahajournals.org/doi/10.1161/...
0111
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 07/09/2025
So much fun AHA #Hypertension25 gala dinner learning history of HTN from Bill Cushman and visiting with friends @anastasiasmihaili.bsky.social @giaconajohn.bsky.social @spjuraschek.bsky.social
0102
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 06/09/2025
@giaconajohn.bsky.social excellent talk highlights that intensive lowering of BP leads to lower not higher risk of OH based on metaanalysis of RCT by @spjuraschek.bsky.social #Hypertension25 Rx should be titrated to seated BP in OH as per 2025 high BP guidelines
264
Reposted by John Giacona, PhD, PA-C
Edgar V. Lerma 🇵🇭 @edgarvlermamd.medsky.network · 06/09/2025
Efficacy and Safety of Baxdrostat in Participants with CKD and Uncontrolled #Hypertension: A Randomized, Double-Blind, Placebo-Controlled Trial ca. 2025 from @asnpublications.bsky.social @escardio.bsky.social #Nephpearls #NephSky #ESCCongress 👉 journals.lww.com/jasn/fulltex...
054
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 06/09/2025
Great dinner celebrating #Hypertension25 together near harbor with UTSW group Angie Price @giaconajohn.bsky.social @robynwei.bsky.social @jesslin23.bsky.social and Mu Huang
083
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 05/09/2025
Dr Karol Watson starts with impactful message top 10 take away message #Hypertension25 high BP as predictor dementia and treatment reduces cognitive decline or dementia by 15% . Once you hit 120/80 , trajectory to high BP is steep. Don’t sit on high BP! @ahascience.bsky.social
073
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 05/09/2025
Ideal BP < 120/80 mmHg! #Hypertension25
070
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 05/09/2025
Congratulations @robynwei.bsky.social RD/ PhD candidate for her poster #Hypertension25 highlighting underutilization of salt substitute use in the US @giaconajohn.bsky.social details in AHA News release newsroom.heart.org/news/u-s-sur... @ahascience.bsky.social
093
Reposted by John Giacona, PhD, PA-C
robynwei.bsky.social @robynwei.bsky.social · 05/09/2025
Honored to present my abstract poster at the AHA #hypertension25 on the prevalence of salt substitute use. Grateful that our work @drwanpen.bsky.social @giaconajohn.bsky.social @jesslin23.bsky.social was also featured in the official AHA news release: newsroom.heart.org/news/u-s-sur...
newsroom.heart.org
U.S. survey finds salt substitutes rarely used by people with high blood pressure
Research Highlights: Despite their effectiveness in lowering sodium intake and managing blood pressure, salt substitutes were rarely used by people with high blood pressure, according to a review of a...
053
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 05/09/2025
Kicked off the day with a run around Baltimore Harbor 🌊🏃‍♂️ at #Hypertension25. A reminder that movement matters — let’s keep championing lifestyle and physical activity as powerful tools to reduce CVD and BP! @ahascience.bsky.social
030
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 05/09/2025
Outstanding review of resistant hypertension at #HTN25 by Drs. @drwanpen.bsky.social , Keith Ferdinand, and Ty Gluckman — from current challenges in care to exciting new agents in the pipeline. Great insights into where the field is heading!
021
Reposted by John Giacona, PhD, PA-C
Jesslin Abraham, M.D. @jesslin23.bsky.social · 04/09/2025
Thank you to AHA for the opportunity to present at AHA HTN scientific session 25 in Baltimore. Having an amazing time meeting and connecting with experts in the field! @drwanpen.bsky.social @giaconajohn.bsky.social @robynwei.bsky.social
173
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 04/09/2025
Great talk #Hypertension25 by @jesslin23.bsky.social in discussing limitations of visual estimation of home BP in clinical decision in Rx HTN in Eyeball study @robynwei.bsky.social @giaconajohn.bsky.social
074
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 04/09/2025
Fantastic opening session at AHA #HTN25 — great energy, insights, and inspiration already flowing. Excited for the great science and rich discussions ahead! @ahascience.bsky.social @drwanpen.bsky.social
001
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 03/09/2025
Got to Baltimore #Hypertension25 so excited to see friends and colleagues talking about high BP ! @ahascience.bsky.social @giaconajohn.bsky.social
0126
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 28/08/2025
❓What’s new in BP care? 🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
093
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 20/08/2025
Join us @jordybc.bsky.social , Keith Ferdinand, and Dan Jones unpacking 2025 AHA/ACC guidelines on Thursday Aug 28 bit.ly/Guideline25W... @UTSWInternalMed @utswheart
097
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 14/08/2025
New 2025 AHA/ACC Hypertension Guidelines are out! You will not want to miss this webinar! Sign up 👇
000
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 04/08/2025
Another great HTN JC by @giaconajohn.bsky.social on AVIM therapy, which just received BDD status. A niche pacemaker for pt with systolic HTN but concerns remain for reduced cardiac output from AV dyssynchrony+ chronic RV pacing. with this high BP variability, how can oscillometric BP be accurate?
011
Reposted by John Giacona, PhD, PA-C
Endocrine Society @endocrinesociety.bsky.social · 14/07/2025
Our latest clinical practice guideline, Primary Aldosteronism (bit.ly/44MbrSv), is now available. The new guideline recommends more widespread screening for a common hormonal cause of high blood pressure known as primary aldosteronism. Read in @endocrinenews.bsky.social: bit.ly/4kFadhv #ENDO2025
01710
Reposted by John Giacona, PhD, PA-C
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 14/07/2025
A medical adrenalectomy? ASIs advance - Baxdrostat in primary aldosteronism now www.nejm.org/doi/full/10.... n = 15 single arm trial from @adinaturcu.bsky.social and @astra-zeneca.bsky.social in @nejm.org ~ 25/10 mm Hg BP lowering and impressive aldosterone level drop #Hypertension #EndoSky
Efficacy and Side-Effect Profile of Baxdrostat in Patients with Primary Aldosteronism.
02310
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 14/07/2025
New PA Endo guideline is also out by experts @anandvaidya17.bsky.social #Cardiosky @hswapnil.medsky.social doi.org/10.1210/clin...
doi.org
Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline
AbstractBackground. Primary aldosteronism (PA), a primary adrenal disorder leading to excessive aldosterone production by one or both adrenal glands, is a
12314
Reposted by John Giacona, PhD, PA-C
NEJM.org @nejm.org · 13/07/2025
In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone production, and hypokalemia. Full SPARK study results: nej.md/40Js1kz #ENDO2025
A figure showing the changes from baseline in systolic blood pressure (SBP), plasma aldosterone–renin ratio (ARR), and serum potassium level for each patient.
02915
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 11/07/2025
Another fun Hypertension JC today. Bedmed trial was disccused by Jesslin Abraham our fellow. @giaconajohn.bsky.social @hkkimphd.bsky.social @utswim.bsky.social
062
John Giacona, PhD, PA-C @giaconajohn.bsky.social · 06/06/2025
Yes! Such a great JC! Loved the multidisciplinary insights
020
Reposted by John Giacona, PhD, PA-C
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/06/2025
The first #ERA25 simultaneous pub CONFIDENCE trial of empagliflozin + finerenone in N = 579 Greater reduction in ACR and BP Note the impressive GFR dip www.nejm.org/doi/full/10....
Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.
34123
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 05/06/2025
Our new paper led by @hkkimphd.bsky.social published today in Circulation that highlights hypertension induced by dietary phosphate excess via FGF23-FGFR4-calcineurin activation of SNS in normal rats bit.ly/43H3cGB @ahascience.bsky.social #cardiosky
142
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 16/05/2025
Although it is getting warmer in Dallas, red Asiatic Lillies seem to enjoy it in my backyard. #magicalgarden
051
Reposted by John Giacona, PhD, PA-C
American College of Cardiology @accintouch.bsky.social · 13/05/2025
The ACC has named Viet Le, DMSc, MPAS, PA-C, FACC, to lead its #CardioSmart patient engagement program. "I'm excited to build on my predecessors' work, providing tools for informed decisions & supporting healthy life journeys." - @vietheartpa.bsky.social More: bit.ly/44UY5VN #CardioSky #MedSky
5217
Reposted by John Giacona, PhD, PA-C
Josh Leisring @joshleisring.bsky.social · 15/05/2025
Don’t forget that 20-30% of patients with RHTN have primary aldosteronism. These patients get extrarenal, BP-independent benefits from MR-blockade. So be sure PA is excluded before reaching for amiloride. #nephsky
0105
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 26/04/2025
Great to visit with friends @k-bunsawat.bsky.social #APS2025 Congrats Ayumi Fukazawa for receiving Henry Pickering abstract recognition!
142
Reposted by John Giacona, PhD, PA-C
Alex Chang, MD @alexchangmd.bsky.social · 12/04/2025
Super interesting work by Dr Vongpatanasin on SGLT2i mechanisms of lowering BP - possibly by decreased renal sympathetic nerve activity independent of glycemic control @drwanpen.bsky.social @nkf-professionals.bsky.social @spjuraschek.bsky.social www.ahajournals.org/doi/10.1161/...
0114
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 19/04/2025
A nice package from AMA today. Grateful to be part of validatebp.org group w Tammy Brady @jordybc.bsky.social @spjuraschek.bsky.social who are serious about certifying good BP monitors for public use. Please check validatebp.org website before spending your money on new BP monitors! #cardiosky
0116
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 09/04/2025
Proud of our PhD student Robyn Wei (also a registered dietician) who present an abstract at our UTSW WISMAC today on salt taste perception and acceptance to salt substitute in a blinded salt taste challenge study. Glad to find out that I prefer SS to regular salt ! @giaconajohn.bsky.social
041
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 31/03/2025
Glad to discuss HTN center model #ACC25. History of HTN is UTSW is rich from Dr. Norman Kaplan to Ron Victor. The room is packed with standing room on. Dr. Commodore-Mensah discuss challenge in doing Health Equity research in the new era. Dr. Ferdinand discuss new drugs in HTN
0133
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 14/03/2025
Fantastic talk by Mark Supiano at IM Grand Rounds this morning highlighting benefits of intensive BP control on cognitive outcomes in older adults from RCTs. Better yet, Legacy effect of SPRINT BP control on MCI and dementia. #Cardiosky #Nephsky @k-bunsawat.bsky.social
062
Reposted by John Giacona, PhD, PA-C
Wanpen Vongpatanasin @drwanpen.bsky.social · 11/03/2025
Congratulations Dr. Han Kim for identifying augmented exercise pressor reflex ⬆️ renal sympathetic nerve and BP response to exercise in the rat model of CKD #Cardiosky #Nephsky ow.ly/IywH50VeKqx
ow.ly
Exercise Pressor Reflex Function Is Augmented in Rats with Chronic Kidney Disease | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology | American Physiological Society
Cardiovascular responses to exercise are exaggerated in chronic kidney disease (CKD) patients. Enhanced sympathetic activation is thought to play a role with the exercise pressor reflex (EPR), a refle...
011