Much of the immunology community relies on human IL-2 to support murine CD8 T-cell expansion in vitro. Although human and murine IL-2 share high similarity in amino acid sequence and exhibit similar b...

Background Colorectal cancer (CRC) is a leading cause of cancer-related death and remains a significant global health challenge. Cancer vaccines have emerged as a promising immunotherapy for long-term...

Fostering the exchange of the latest immunological knowledge

Mattingly et al. use human lung cells to show that virus-specific CD8+ tissue-resident memory T cells trigger epithelial antiviral defenses via IFNγ. This early protective response varies by epithelial subset, restricts influenza infection, and highlights the importance of Trm-epithelial cell crosstalk in mediating respiratory virus control.

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Dr. Shruti Naik is one of the immunologists in New York state behind NY-CURES, advocating for state investment in biomedical research.

Nature - The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.

Letters: Dr Robin Lovell-Badge and Prof Emma Robinson respond to an editorial on using new technologies to reduce the reliance on animal experiments

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Mattingly et al. use human lung cells to show that virus-specific CD8+ tissue-resident memory T cells trigger epithelial antiviral defenses via IFNγ. This early protective response varies by epithelial subset, restricts influenza infection, and highlights the importance of Trm-epithelial cell crosstalk in mediating respiratory virus control.

In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.

The need to suppress a patient’s immune system after the transplantation of allogeneic cells is associated with wide-ranging side effects. We report the outcomes of transplantation of genetically m...

Committee gives first hint that policymakers might preserve, rather than slash, funding for US National Science Foundation and other agencies.

Abstract. Macrophages are versatile innate immune cells that act as sentinels, warriors, and healers in virtually every tissue. This review synthesizes cur

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United States Senate Committee on Appropriations

The Women’s Health Initiative has produced numerous influential findings