Reposted by Ella SayMari Sosa @marisosa.bsky.social · 03/04/2026It was an honor to be part of this work! Getting the sparse knockout in CA1 to work with dual color 2p imaging — letting us compare Syntaxin3-KO cells to WT cells in the same animal — was particularly challenging and fun 😄 051
Reposted by Ella SayMark Plitt @markplitt.bsky.social · 03/04/2026My final paper from grad school is out! Thank you to @marisosa.bsky.social @ellasay.bsky.social and my co-first author Konstantin Kaganovsky! We show that reward and novelty coding in the hippocampus requires a specific membrane fusion protein implicated in activity-dependent AMPAR mobilization! 0145
Reposted by Ella SayEmily A. Aery Jones @emilyaeryjones.bsky.social · 01/04/2026My main postdoc work is now published: www.nature.com/articles/s41...! We (myself, Isabel Low, Frances Cho, and @lgiocomo.bsky.social) discovered task-relevant remote representations in entorhinal cortex independent of CA1. #paperthread below! 1/13nature.comEntorhinal cortex represents task-relevant remote locations independently of CA1 - Nature NeuroscienceNeurons in medial entorhinal cortex collectively represent discrete nonlocal positions during immobility. During this nonlocal coding, CA1 is uncoupled from entorhinal cortex. These representations ar... 67729
Reposted by Ella SayMari Sosa @marisosa.bsky.social · 22/09/2025The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.sosaneurolab.comSosa Lab 09337
Reposted by Ella SayMari Sosa @marisosa.bsky.social · 12/06/2025It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...nature.comA flexible hippocampal population code for experience relative to reward - Nature NeuroscienceSosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu... 912940