Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 10/09/2026Last call! Applicant review starts tomorrow! 000
Reposted by Jeff Bourgeois, PhDLiuyang Wang @wallacewly.bsky.social · 31/08/2026What happens when AI meets human genetics? We integrate single-cell sQTL mapping with fine-mapping and deep-learning splicing prediction to uncover disease causal genetic variants and their mechanisms. Read our new study in Genome Biology: link.springer.com/article/10.1...link.springer.comIntegrating single-cell sQTL mapping with deep-learning splicing prediction identifies causal variants under influenza infection - Genome BiologyBackground Realizing the full potential of human genetics requires identifying causal variants and genes underlying association signals. Molecular quantitative trait locus (molQTL) analyses, such as e... 121
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 25/08/2026Never in my career have I sent a paper to so many people with the caption “TOLD YOU SO.” 010
Reposted by Jeff Bourgeois, PhDProceedings of the National Academy of Sciences @pnas.org · 24/08/2026Lyme disease risk in New York State is best predicted by the abundance of white-footed mice and the red oak acorns that mice eat, not by white-tailed deer numbers, according to a study. The mice excel at transmitting the Lyme disease bacterium to ticks. In PNAS: ow.ly/FMu850ZEOLm 2125
Reposted by Jeff Bourgeois, PhDGeoff Findlay @geofffindlay.bsky.social · 10/08/2026Holy Cross Biology is hiring this year for two positions! I am chairing our search in molecular biology: apply.interfolio.com/191081 We're looking for candidates committed to inclusive excellence in teaching and who will expand our capacity for undergraduate research. I'm happy to field questions.apply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 052
Reposted by Jeff Bourgeois, PhDAndreas Bäumler @abaumler.bsky.social · 06/08/2026Nominations for the 2027 New Voices in Infection and Immunity cohort are now open: asm.org/NewVoices-IA... 1911
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 07/08/2026Honored to have been part of this series. Many thanks to @asm.org and the mentors and colleagues who nominated me. And shoutout to my amazing technician and graduate student who both led the charge on the research and writing. 040
Reposted by Jeff Bourgeois, PhDBrian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 29/07/2026Devastated to report that Brandon Jutras passed away a day or two ago. Brandon earned his PhD with me. He went on to be an Associate Professor at Northwestern University School of Medicine and a super star in Lyme research. A loving husband and father, a sincere friend, and a brilliant scientist 💔 12468
Reposted by Jeff Bourgeois, PhDDrug Monkey @drugmonkey.bsky.social · 27/07/2026Note: “Letters of collaboration should be limited to stating the intent to collaborate or provide material support as described in the application and should not contain endorsements or additional information about or evaluations of the proposed project. “ 31917
Reposted by Jeff Bourgeois, PhDSarah Taber @sarahtaber.bsky.social · 18/07/2026A quick word on Taco Bell: That's where we found the suspected lettuce, and it's not bc Taco Bell is gross. It's bc Taco Bell is REALLY GOOD at tracing product! Keeping track of exactly where they got their ingredients, & exactly what restaurants each shipment of ingredients went to! 438249785142
Reposted by Jeff Bourgeois, PhDAdam Serwer @adamserwer.bsky.social · 18/07/2026Like Shakespeare, the Greek classics have been interpreted countless times in countless places. If you do antigone in China, are you supposed to scour the place for Greek actors? Nolan’s Odyssey is an American film so it looks like America. bsky.app/profile/beau... 771422146
Reposted by Jeff Bourgeois, PhDAndrew Blum @ablum.bsky.social · 14/07/2026Last re-up of this thread because I’m hearing lots of similar stories to mine and I do think it’s important. tl;dr If you think there’s any chance AT ALL you may be having a heart attack, go to the ER. 0329
Reposted by Jeff Bourgeois, PhDYi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 10/07/2026My department @tuftsvet.bsky.social (Tufts Vet School) is recruiting an Assistant/Associate/Full Professor with the expertise on infectious disease ecology and evolution. Feel free to repost/forward this. Here is the link for the application: apply.interfolio.com/187991apply.interfolio.com Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio 021
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 23/06/2026First time taking the Bourgeois Lab to a conference! Lots of new ideas to try out back in Worcester thanks @bostonbacteria.bsky.social! 071
Reposted by Jeff Bourgeois, PhDMarco Fumasoni @marcofumasoni.bsky.social · 19/06/2026Our paper on the evolution of cellular miniaturization is now out in PNAS! www.pnas.org/doi/10.1073/... A short recap 🧵pnas.orgPNASProceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans... 24520
Reposted by Jeff Bourgeois, PhDDrug Monkey @drugmonkey.bsky.social · 11/06/2026More on the RFI about capping NIH grant awards drugmonkey.wordpress.com/2026/06/10/m...drugmonkey.wordpress.comMore on the RFI about capping NIH grant awardsI blew it. In rage-reading the RFI and spleen venting about it, I missed the fact they had provided the update to Sally Rockey’s old “mythbusting” analysis of grants-per-PI. I did… 021
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 05/06/2026Do you pair experimental and computational biology techniques (or know someone who does)? Come be my colleague! wpi.wd5.myworkdayjobs.com/en-US/WPI_Ex...wpi.wd5.myworkdayjobs.comAssistant Professor | Biology & BiotechnologyJOB TITLE Assistant Professor | Biology & Biotechnology LOCATION Worcester DEPARTMENT NAME Biology & Biotechnology DIVISION NAME Worcester Polytechnic Institute - WPI JOB DESCRIPTION SUMMARY T... 000
Reposted by Jeff Bourgeois, PhDBay Area Lyme Foundation @bayarealyme.bsky.social · 29/05/2026It’s time to rethink one of the biggest myths about #Lymedisease: the “bullseye” rash. Liz Horn, PhD, MBI, PI of @lymebiobank.bsky.social talks about how Lyme rashes can look solid, blotchy, or like a bruise—and many patients never see a classic target or a rash at all. #LymeAwarenessMonth 164
Reposted by Jeff Bourgeois, PhDMark Peifer (He, him) @peiferlabunc.bsky.social · 24/05/2026By the way, @dshb-antibodies.bsky.social is a non-profit that sells quality antibodies to many proteins at exceptionally reasonable prices, without AI generated faux-validation images. Check them out. dshb.biology.uiowa.edudshb.biology.uiowa.eduDevelopmental Studies Hybridoma Bank - DSHBHigh quality, low cost antibodies. 29343
Reposted by Jeff Bourgeois, PhDMcSweeney's @mcsweeneys.net · 12/05/2026"If you are female, drink one shot immediately. Underrepresented minority: one shot. Both: three shots, because intersectionality. Each shot will help you lower your expectations for fairness before you read through the comments." www.mcsweeneys.net/articles/rev...mcsweeneys.netReviewing Course Evaluations: The Drinking Game“If you are female, drink one shot immediately. Underrepresented minority: one shot. Both: three shots, because intersectionality. Each shot will help you lo... 314860
Reposted by Jeff Bourgeois, PhDBrian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 11/05/2026Just announced! This year’s Tick Borne Disease Research Program of CDMRP. cdmrp.health.mil/funding/tbdrp #MicroSkycdmrp.health.milFunding Opportunities-FY26 TBDRP, Congressionally Directed Medical Research Programs (CDMRP)TBDRP funding opportunities currently available 074
Reposted by Jeff Bourgeois, PhDJutras Lab @jutraslab.bsky.social · 07/05/2026Osas’s approach uses monoclonal antibodies to capture and detect the very unusual peptidoglycan fragments #glycotime now shown to be released by several species of Borrelia that cause Lyme disease 🤯. Check it out 👇 www.medrxiv.org/content/10.6...medrxiv.orgA direct, urine-based test to diagnose acute Lyme disease using actively secreted peptidoglycan as a biomarkerLyme disease is a growing and prominent human health problem caused by a group of spirochaetal bacteria that belong to the Borrelia genus. Persistent Lyme disease infection produces a multi-system dis... 162
Reposted by Jeff Bourgeois, PhDZoe McElligott @nanopharmnc.bsky.social · 29/04/2026We work in sexually dimorphic brain regions and signaling elements that have sex differences. It is EQUALLY interesting when we find sex differences as when we do not, but if we don't look, we don't know. (1) 1199
Reposted by Jeff Bourgeois, PhDSimon Hammann @simonhammann.bsky.social · 20/04/2026Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey. 191958537
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 08/04/2026The Bourgeois Lab is recruiting a postdoc to work on our DoD-funded human genetics project aimed at understanding Lyme disease outcomes. wpi.wd5.myworkdayjobs.com/WPI_External... 064
Reposted by Jeff Bourgeois, PhDSaloni @scientificdiscovery.dev · 05/04/2026Few people are aware of how much progress has been made against cancers. Leukemia is probably the most striking example. Before the 1970s, most children affected by leukemia would soon die from it. Now, most children in rich countries survive. ourworldindata.org/childhood-le... 332497
Reposted by Jeff Bourgeois, PhDBrianne Gorod @briannegorod.bsky.social · 31/03/2026More from J. Jackson on what today's #SCOTUS decision could mean: "So, to put it bluntly, the Court could be ushering in an era of unprofessional and unsafe medical care administered by effectively unsupervised healthcare providers." 12910
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 31/03/2026Such a cool project and potentially such a potent weapon against tick-borne disease. 140
Reposted by Jeff Bourgeois, PhDMariko Bennett @nachoriko.bsky.social · 24/03/2026I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity. 491706568
Reposted by Jeff Bourgeois, PhDMobius Stripper @mobiusstripper.bsky.social · 19/03/2026Me, being led away by the secret service after releasing thousands of gophers at the Capitol: "You don't understand! It's a scientifically proven way to revive a desolate place! I'm a patriot!" www.popularmechanics.com/science/envi...popularmechanics.com43 Years Ago, Scientists Dropped Gophers Onto a Volcano. Today, They’re Tiny Heroes.It started as a go-for-broke experiment, but it wound up saving an ecosystem. 1374734931
Reposted by Jeff Bourgeois, PhDPaul Carini @uncultured.carinilab.com · 17/03/2026And if you have not been accepted, understand that this is a VERY weird time for grad admissions. Lack of acceptance may not be due to YOU, but due to uncontrollable factors at the university. Keep trying in the future. 14023
Reposted by Jeff Bourgeois, PhDAlex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · 13/03/2026When Salmonella typhimurium invades cells that line the intestine, it uses a syringe-like type III secretion system to inject dozens of proteins (effectors) into the host cell cytoplasm. This beautiful descriptive study provides the first chronology of the order in which the effectors are injected.biorxiv.org 2155
Reposted by Jeff Bourgeois, PhDDavid Weiss @dweisslab.bsky.social · 12/03/2026Bacteria in our BRAINS??! We observed translocation of bacteria from the gut to the brain via the vagus nerve. This occurred after high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism. journals.plos.org/plosbiology/...journals.plos.orgTranslocation of bacteria from the gut to the brain in miceRecent studies link gut dysbiosis to neurological disease, but the underlying mechanisms remain unclear. This study shows that a high-fat diet increases gut permeability and enables bacterial transloc... 44119
Reposted by Jeff Bourgeois, PhDSjors Scheres @sjorsscheres.bsky.social · 16/10/2025I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗 beta.ideas.lego.com/product-idea...beta.ideas.lego.comBiological Laboratory | LEGO® IdeasThis is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ… 8223131
Reposted by Jeff Bourgeois, PhDMwahahahahahadScientist @mads100tist.bsky.social · 25/02/2026Motion to stop referring to it as Next Generation Sequencing. That's like saying The Matrix is a recent movie 3022933
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 24/02/2026Showing this to my students when they ask why we only have computer-free, in-person assignments. 020
Reposted by Jeff Bourgeois, PhDCarl Zimmer @carlzimmer.com · 18/02/2026Scientists have seen Asgard archaea crawling for the first time. When it comes to the origin of eukaryotes, this is like seeing a feathered dinosaur in the wild. (Video courtesy of Philipp Ralder) 10469135
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 14/02/2026My first time doing an independent tissue culture experiment in Worcester since 2016. Godspeed, little ones. 120
Reposted by Jeff Bourgeois, PhDDorothy Bishop @deevybee.bsky.social · 11/02/2026V useful piece dispelling myths about NIH policy on open access upstream.force11.org/cost-of-conf...upstream.force11.orgThe Cost of Confusion: Dispelling Myths about the NIH Public Access Policy and Article Processing ChargesLast July, the NIH issued an RFI on limiting direct spending on article processing charges (APCs). Over 900 public responses offered valuable perspectives but also exposed widespread misconceptions ab... 01613
Reposted by Jeff Bourgeois, PhDStu West @stuwest.bsky.social · 09/02/2026A super handy database to help support academic society journals and other ethical publishing. academic.oup.com/jeb/article/...academic.oup.comTime to publish responsibly: DAFNEE, a database of academia-friendly journals in ecology and evolutionary biologyAbstract. The current economics of scientific publishing reveal a profound imbalance: academia pays prices far exceeding the actual costs of publication. R 1108
Reposted by Jeff Bourgeois, PhDPaul Carini @uncultured.carinilab.com · 19/01/2026Not exactly advice I give, but I believe this period is shaping the next gen of scientific leaders with unique skillsets. I wrote a bit about it here: uncultured.carinilab.com/p/an-open-le...uncultured.carinilab.comAn Open Letter to Graduating PhDs in a Post-Federal Science WorldJuly 15, 2025 096
Reposted by Jeff Bourgeois, PhDtuftslyme.bsky.social @tuftslyme.bsky.social · 15/01/2026New publication from Pete Gwynne from @TuftsLyme in PlosPathogens doing a deep dive into lipid scavenging by B. burgdorferi. Once again and example of Bb being lazy and depending on its environment 😀 journals.plos.org/plospathogen...journals.plos.orgLipid scavenging by the Lyme disease spirochete Borrelia burgdorferiAuthor summary Lyme disease is caused by a bacterium, Borrelia burgdorferi, which has an unusually small genome; it scavenges most of the nutrients it needs to survive from its hosts. This scavenging ... 072
Reposted by Jeff Bourgeois, PhDJavier Apfeld @javierapfeld.bsky.social · 06/01/2026🚨My department is hiring a full-time Assistant Teaching Professor to teach undergrad Genetics & Genomics, upper-level Genomics, and an inquiry-based Computational Genomics course where students can do authentic research. 🧬💻 I’m on the search committee. DM me if you’re interested. Please share! 🙏northeastern.wd1.myworkdayjobs.comAssistant Teaching Professor, BiologyAbout the Opportunity About the Opportunity: We invite applications from qualified candidates for a full-time Non-Tenure-Track (NTT) Assistant Teaching Professor faculty position within the Department... 02027
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 02/12/2025Press release was delayed because of the change in institution and the shutdown, but we’re officially doing stuff! www.wpi.edu/news/wpi-res... 4110
Jeff Bourgeois, PhD @bourgeoisjs.bsky.social · 01/12/2025The most consistent experimental work I do in my lab these days is sneak into all the molecular biology kits and throw out the elution buffers and write “elute with water” on all of the printed protocols… all while my lab laughs at me. PI life is weird. 260