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Yi-Pin Lin Lab@TuftsVet

@yiplin.bsky.social
49 followers 19 following 43 posts

A Biologist, Professor, Taiwanese American, and Backpacking Traveler always in adventurous trips 🇺🇸 🇹🇼

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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 10/07/2026
My department @tuftsvet.bsky.social (Tufts Vet School) is recruiting an Assistant/Associate/Full Professor with the expertise on infectious disease ecology and evolution. Feel free to repost/forward this. Here is the link for the application: apply.interfolio.com/187991
apply.interfolio.com
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 02/02/2026
10 year anniversary as a professor to have my own lab! All started from Feb. 1, 2016 moving to Wadsworth and Feb. 1, 2024 moving to Cummings School of Veterinary Medicine at Tufts University. Where will I be in next 10 year anniversary? 😉
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 23/12/2025
Our work was highlighted as top research stories in Tufts University social media "Tufts Now" ("Alternative Approach to Lyme Disease Vaccine Development Shows Promise in Pre-clinical Models ")! bit.ly/4jf13cG
bit.ly
Top Research Stories of 2025
Tufts University faculty have been discovering everything from how to measure stress levels and make cancer vaccines work to learning that coffee seems to protect health
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 13/12/2025
Happy holidays/Merry Christmas/Happy New Year! From Lin lab 🎄 🎅 Lin lab tradition: everyone gets a bottle of wines Yi-Pin collected when traveling all over the world this year! (We have wines from Japan, Australia, Taiwan, Turkey, & France)
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 18/09/2025
Koala. 🐨 Aww…. Whole complement conference of people (200 people) are waiting to pet koala ($100 to pet for 10 seconds 🤣) glad this is included in the conference registration fee.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 17/09/2025
My second time in International Complement Workshop. So happy to meet my Danish collaborator and friend, Gregers Andersen! my Swedish collaborator, Anna Blom (thank you for the the tick anti-complement OmCI) and Meiqing Shi, George Chaconas’s former postdoc (current professor in Univ Maryland)!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 15/09/2025
After traveling thru N. America (Chicago), Europe (Istanbul), Egypt (Cairo), Shanghai (Asia), finally I’m in Brisbane, Australia! Excited to meet old friends and new colleagues talking about tick and Lyme bacteria anti-complement proteins in International Complement Workshop (ICW).
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 10/09/2025
Tick meeting is done, now I’m traveling to Australia for international complement conference (ICW). First stop, Istanbul, Turkey! Before that, absolutely enjoy some vodka cocktail in the lounge at Chicago airport!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 09/09/2025
I gave a talk for the story of our CspZ Lyme disease vaccines. I enjoy this tick-Lyme conference for meeting old and new friends I met people in the pic when we all were trainee. We now all have our own lab and field of expertise in different university!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 09/09/2025
I’m in Chicago! Welcome to International Conference of Lyme disease and other tickborne diseases (ICLB)!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 08/09/2025
My September business + personal trip starts! The first stop: Chicago for ICLB conference (international conferences of Lyme Borreliosis)
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 06/09/2025
The tradition of any friends visiting me and going with me to Boston is to have lobster! Of course Ai my collaborator and friend would need a lobster 🦞
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 06/09/2025
Autumn is the bird banding season because of the migration. Working on ticks,birds, Lyme again! My collaborator Ai Takano and I visited our local bird banding station. Met so many enthusiastic volunteers bird banders!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/09/2025
Today is also our research day at Cummings School of Veterinary Medicine at Tufts University. Thanks for my DVM students, Renner Thomas and Audrey Ponder (Very interesting work of wild birds), and PhD student, Sergio Hernandez giving great talks. So proud that Sergio got the best poster award!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/09/2025
Remember I went to Japan to collect ticks this May? So happy to host my collaborator, Ai Takano, from Yamaguchi Univ. at Japan to to talk about her work on tickborne pathogenss, wildlife animals, and Lyme disease in Japan. IImpressed on >200 people attending her talk! Very relevant talk!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/09/2025
My postdoc boss, John Leong, invited me to give a talk at Tufts Medical School yesterday. Very happy to see many old and new friends/colleagues as well as my drinking picture still on the refrigerator in the lab. I have no idea but I look nice and young 🤣
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 24/08/2025
Complement kills Lyme disease bacteria, but bacteria evolve to produce anti-complement proteins to escape killing. Our work @jimmunol.bsky.social turned such escaping to a killing strategy as a Pre-exposure prophylaxis, which can a hope for people refusing vaccines to handle LD. shorturl.at/BagpT
shorturl.at
Complement therapeutic factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infections
Abstract. Lyme disease (LD) is the most common vector-borne disease in the northern hemisphere and is caused by the bacteria Borrelia burgdorferi sensu lat
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/06/2025
We then have to be very careful to collect samples (blood) and take out the ticks. Some birds (like Veery) really had loads of the ticks. Let’s culture the Lyme bacteria from ticks and see what genotypes we got!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/06/2025
The first step of trapping the birds is to identify the sites that is at the edge of the wood so you’ll have lots of birds passing by. Setting up the net absolutely needs some efforts. Check on my DVM student, Audrey, working very hard to set up the net
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/06/2025
The most challenging work of mist netting is to take the birds from entangled net while the birds are screaming. Here are examples of woodpeckers and catbirds. My DVM student, Renner, worked very hard to take out the birds from the net. That’s his first time!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 05/06/2025
Come to join my technician, Miranda, and the summer DVM students, Renner and Audrey. We are going to the field to trap birds in understanding wild birds’ role in tickborne diseases/Lyme disease! Special thanks for Alan Dupuis, my colleague/friend at Wadsworth visiting and training us!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 21/05/2025
Although Ixodes persulcatus tick is the major tick species transmitting human Lyme infectious bacteria in northern Asia, the other tick species can also transmit those human important Lyme bacteria. That is “Ixodes pavlovski “ take a look to see how we can differentiate them.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 21/05/2025
In Hokkaido, there’re three major tick species that can be collected via dragging (Ixodes persulcatus, Ixodes ovatus, and Haemaphysalis spp). I. Persulcatus transmits Lyme disease bacteria in northern Asia. are focusing on this tick but differentiating tick species is not easy
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 21/05/2025
We’re Traveling to Nemuro, Hokkaido to collect ticks. This site is also a bird banding station as it is on the fall migration route of wild birds. We met local bird bander setting up the mist net, saw the endangered red crown crane, learned banders study the bird migration route
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 20/05/2025
Many eagle species here in Kushiro wildlife conservation center are endangered and specific to Japan including White-tailed eagles and Blakiston Fish Owls. Scientists and DVMs here also search for their nests, sample/band the birds to monitor their health and also track their migration.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 20/05/2025
At Kushiro, Japan visiting Dr. Saito, the lead scientist in Kushiro Marsh Wildlife Conservation Center. They specialise in rehabilitation of endangered eagles and owls. Many DVMs here treated wildlife animals, put reporters to prepare their release.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 19/05/2025
Field season starts so I’m heading to Sapporo (Hokkaido) at Japan to collect the Asian Ixodes ticks carrying Lyme disease bacteria! Good luck to get many ticks!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 09/04/2025
Thanks for #TuftsUnivesrity sharing our story with @mebottazzi.bsky.social, WenHsiang Chen, Kalvis Brangulis, Chinglin Hsieh to turn a bacterial protein that people gave up hope into a very powerful Lyme disease vaccine candidate! shorturl.at/nESG5 @bcmhouston.bsky.social @tuftsvet.bsky.social
shorturl.at
Alternative Approach to Lyme Disease Vaccine Development Shows Promise in Pre-clinical Models
Research team finds genetic engineered Lyme bacterial proteins could offer long-standing protection against infection while requiring fewer vaccinations.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 07/04/2025
Excited to share our work published today @naturecomms.bsky.social with Kalvis Brangulis, @bcmhouston.bsky.social (@mebottazzi.bsky.social, Wen-Hsiang Chen), Ching-Lin Hsieh, & Utpal Pal. We applied structural-based design to approach the challenges of Lyme disease vaccines. shorturl.at/8Gvh4
shorturl.at
Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine - Nature Communications
The outer surface protein CspZ is a potential vaccine candidate of Borrelia burgdorferi for Lyme disease prevention. Here, using structure-based design, the authors generate a mutant CspZ protein with...
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 28/03/2025
Finally, Time for my talk! “Tick-pathogen anti-complement evolution dictates host immunomodulation for multimodal Lyme borreliae transmission” Photo credits from Peter Kraiczy’s student, Flavia.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 27/03/2025
Always great to meet up with old friends/collaborators Peter, Klemen, Kalvis in the ticks meeting at Weimar (ISTTBD). This is the meeting I learned the most information relevant to my research in recent years!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 25/03/2025
Finally after three flights, three Germany national rail train ride (all three rides delayed), I arrived at Weimar, Germany. All I need is to go to bed immediately 🥱 Ready for the exciting International Symposium of tick borne diseases conference (ISTTBD) tomorrow!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 11/02/2025
Very happy to announce that the website of Lin lab at Tufts University School of Veterinary Medicine! is online! sites.tufts.edu/yipinlinlab/
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Reposted by Yi-Pin Lin Lab@TuftsVet
The Sydney Morning Herald (unofficial) @smhaustralia.nzcow.com · 30/12/2024
📢 Yi-Pin Lin has holidayed in 120 nations over the past decade, but there was one country he had always dreamed of visiting, but was too afraid. Until now. 👉 18+ news & weather bots
smh.com.au
Ignoring warnings, tourists are heading to a former no-go country
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Reposted by Yi-Pin Lin Lab@TuftsVet
Brian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 17/12/2024
Cool news from Kalvis Brangulis, Peter Kraiczy, and Yi-Pin Lin CspZ variant-specific interaction with Factor H incorporates a metal site to support Lyme borreliae complement evasion 🦠🧫🧪🔬🧬 #MicroSky www.jbc.org/article/S002...
Structural images of CspZ
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 31/01/2025
I was interviewed by a company, who is interested in providing general public information of Lyme disease prevention. I'd say the information there is mostly correct and fair if you want to learn the "drama/history/development" of Lyme disease prevention! www.youtube.com/watch?v=q8ut...
youtube.com
Why the Lyme Disease Vaccine Has Taken So Long
YouTube video by Greenbelly
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 29/01/2025
15 years ago I was a junior postdoc starting the Lyme disease research in UMass Medical School. 15 years later, I was invited to come back “home” to give my talk, shared how my career to where I am! I think I’m now officially coming back to MA’s biomedical science community!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 02/01/2025
My department has an opening for an Assistant/Associate Professor of infectious diseases. The job ad can be found here (apply.interfolio.com/161178). Please feel free to share this job announcement with your colleagues!
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 30/12/2024
Never thought my first interview on major media is not about my Lyme disease research but my side job as an adventurous backpacker!😆 Thanks for the New York Times story of my thanksgiving trip in Afghanistan by David and Elise. tinyurl.com/4ze4vjhf
tinyurl.com
Ignoring Warnings, a Growing Band of Tourists Venture to Afghanistan
With the war now over, the Taliban are welcoming foreign travelers, even as governments advise their citizens to stay away.
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Yi-Pin Lin Lab@TuftsVet @yiplin.bsky.social · 24/12/2024
Merry Christmas 🎄🤶 My technician Carly gave me this Christmas gift “the pig made by her”. Moving the lab is tough. We did a lot this year & thank you for the help and we made it @tuftsvet !
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