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Lyme Disease Biobank

@lymebiobank.bsky.social
125 followers 57 following 109 posts

Non-profit providing human biological samples to investigators developing better tests for Lyme and tick-borne infections. Whole blood, serum, plasma, & urine available from people with early Lyme, persistent Lyme, & controls. We also have a tissue bank.

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Lyme Disease Biobank @lymebiobank.bsky.social · 25/08/2026
Really interesting article about a 35 year study in PNAS showing in forests with oak trees, more acorns = more mice the following year, and more nymphal ticks the year after that. Acorn masting could predict Lyme disease 2 years later. Science is so cool! www.medicaldaily.com/acorn-crops-...
medicaldaily.com
Thirty-Five Years of Forest Data Suggest Acorn Crops Predict Lyme Risk Better Than Deer Counts Do
A 35-year study found that deer numbers did not predict tick density in one forest. Acorns and mice did. What does it mean for tick prevention?
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Lyme Disease Biobank @lymebiobank.bsky.social · 10/08/2026
JAMA article about Lyme disease - highlights gaps in testing and new prevention strategies in development. Acknowledges that EM doesn't appear in all patients and treatment options haven't changed in 25 years. Great quotes from my colleagues, too! jamanetwork.com/journals/jam...
jamanetwork.com
Lyme Disease Is Outpacing Medical Advances
This Medical News article discusses the emerging advances in Lyme disease diagnostics, prevention, and therapeutics as well as the practical challenges that continue to limit innovation.
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Lyme Disease Biobank @lymebiobank.bsky.social · 05/08/2026
Informative article from the Atlantic about how to reduce the tick population - Dr. Sam Telford estimates that 1 deer can support 3 million ticks over the breeding season. Yikes! And great quotes from Dr. Jean Tsao about deer crack..... www.theatlantic.com/health/2026/...
theatlantic.com
Kill the Ticks
America needs a bigger plan to control its tick problem.
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Lyme Disease Biobank @lymebiobank.bsky.social · 04/08/2026
New article from SF Chronicle describes the rise of tick-borne disease in CA. It's behind a paywall, so here are some "fun" facts about ticks in the Golden State. 1/6 www.sfchronicle.com/opinion/open...
sfchronicle.com
Tick-borne diseases on the rise throughout California
OPINION: If you think that Lyme disease and other illnesses caused by tick bites aren’t a problem that Californians have to worry about, you’d best think again.
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Lyme Disease Biobank @lymebiobank.bsky.social · 31/07/2026
Dr. Luis Marcos and colleagues found tick-borne viruses (Bourbon and Heartland) in patient samples from Long Island. www.easthamptonstar.com/villages-hea... pubmed.ncbi.nlm.nih.gov/42119530/
easthamptonstar.com
New Tick-Borne Virus Makes First Appearance in New York | The East Hampton Star
The Bourbon virus, a potentially deadly tick-borne disease first discovered in 2014 in a man from Bourbon County, Kansas, has recently shown up in New York State, and the most common tick on the East ...
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Lyme Disease Biobank @lymebiobank.bsky.social · 24/07/2026
New editorial summarizes 6 articles about Lyme Borreliosis: classification, clinical follow-up, treatment of persistent symptoms, epidemiology, vaccine modeling, and the patient and economic burden of chronic tick-borne illness. Article 2 is from our biobank. www.frontiersin.org/journals/med...
frontiersin.org
Frontiers | Editorial: Evolving strategies in Lyme borreliosis treatment and prevention
Together, these studies provide a comprehensive and timely overview of the current landscape in Lyme borreliosis research-demonstrating how improved classifi...
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Lyme Disease Biobank @lymebiobank.bsky.social · 15/07/2026
Really excited the IGenex manuscript was published today showing iDART immunoblots identify more cases than standard two-tier testing, using CDC and LDB samples. These IBs have the 1st and 2nd tiers in a single step with broader coverage. journals.asm.org/doi/10.1128/...
journals.asm.org
Single-step immunoblot tests with recombinant protein antigens for detecting IgG and IgM antibodies in Lyme disease | Microbiology Spectrum
The immunoblot (IB) tests described here are one-step tests that separately detect IgG and IgM antibodies for the serological diagnosis of Lyme disease in the United States. The IB tests are more sens...
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Lyme Disease Biobank @lymebiobank.bsky.social · 25/06/2026
Boston University is recruiting participants 1) bitten by a tick within the last 3 days OR 2) have a clinically diagnosed Lyme rash to test a microneedle patch to try to detect Lyme bacteria at the bite site/rash. bostonu.qualtrics.com/jfe/form/SV_...
Flyer describing Lyme research study at Boston University.
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Lyme Disease Biobank @lymebiobank.bsky.social · 19/06/2026
Informative article from @npr.org about the tick problem, the deer "party bus", and what communities are doing about it. Prevention is still our best defense. www.npr.org/2026/06/19/n...
npr.org
Tick season is getting worse. Can managing deer help?
Health officials and researchers hope that efforts to control deer populations, which serve as "party buses" for mating ticks, can reverse the tide of ticks and the illnesses they cause.
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Reposted by Lyme Disease Biobank
COTBDAA @coloradoticks.bsky.social · 11/05/2026
FY26 TBDRP funding opportunities are now live! Visit: cdmrp.health.mil/funding/tbdrp @lymenews.bsky.social @bayarealyme.bsky.social #Tickbornediseases #Lymedisease #Research #CongenitalLyme #Congenitaldisease #TBDRP #CDMRP
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Lyme Disease Biobank @lymebiobank.bsky.social · 11/05/2026
Preapplications for Lyme and tick-borne disease due July 22, 2026 at 5 pm EST.
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Lyme Disease Biobank @lymebiobank.bsky.social · 03/05/2026
Happy Lyme Awareness Month to all who celebrate! Check out TickAttack! a microgame designed for all ages by Mary Ann Comunale and team @DrexelUniv . Learn how to avoid ticks & tickbornediseases. Now on Apple (apple.co/3TTjA1X) & Google (bit.ly/3xx6qQP).
apple.co
TickAttack! App - App Store
Download TickAttack! by Drexel University on the App Store. See screenshots, ratings and reviews, user tips, and more apps like TickAttack!.
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Lyme Disease Biobank @lymebiobank.bsky.social · 01/05/2026
Want to learn more about Lyme Disease Biobank and how these samples are fueling the research engine? Check out the podcast. 👇
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Lyme Disease Biobank @lymebiobank.bsky.social · 27/04/2026
Interested in advances in Lyme research in the past 18 months? Attend the State of the Science webinar April 30 with Nicole Bell and Bonnie Crater from Center for Lyme Action. Register below - it's free. membercompass.ilads.org/events/webin...
membercompass.ilads.org
Webinar - State of Lyme Disease Research - International Lyme And Associated Diseases Society, Inc.
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Lyme Disease Biobank @lymebiobank.bsky.social · 20/04/2026
Check out @lymenews.bsky.social blog about AI chatbots and health privacy. www.lymedisease.org/what-you-sho...
lymedisease.org
What You Should Know Before Using AI Chatbots or Health Apps | LymeDisease.org
AI tools are becoming a go-to source for health advice. A recent survey from KFF found that 1 in 6 people use AI chatbots for health questions each month.
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Lyme Disease Biobank @lymebiobank.bsky.social · 05/03/2026
New article demonstrates utility of TBDCapSeq and VirCapSeq-VERT (capture sequencing assays using Illumina) on MinION, Oxford Nanopore's portable sequencer. Another step towards bringing NGS diagnostics to clinical labs. link.springer.com/article/10.1...
link.springer.com
Adaptation of custom capture sequencing panels to the Oxford Nanopore MinION platform - Molecular Biology Reports
Background Next generation sequencing (NGS) remains underutilized in clinical microbiology applications despite providing broad pathogen spectrum detection superior to other molecular methods. This is...
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Lyme Disease Biobank @lymebiobank.bsky.social · 02/03/2026
Great blog about James Bruzzese, MD, and his quest to help patients with Lyme and tick-borne illness including his call to action for the next generation of medical professionals. (Yes - medical students would benefit from more than 1 lecture on Lyme disease).
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Lyme Disease Biobank @lymebiobank.bsky.social · 01/03/2026
If you haven't seen the CDMRP FY26 funding opportunities. 👇
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Lyme Disease Biobank @lymebiobank.bsky.social · 20/02/2026
Great interview with @bayarealyme.bsky.social executive director David Walsey. He highlights 3 things that need to happen in the Lyme field: recognition of patients, more research funding (private and federal), and education of clinicians.
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Lyme Disease Biobank @lymebiobank.bsky.social · 13/02/2026
Great Q&A with @jutraslab.bsky.social about the role of peptidoglycan in Lyme arthritis. Nice summary of elegant and complex experiments. Is PG important in other complex presentations of Lyme, like carditis and neuroborreliosis? www.healio.com/news/rheumat...
healio.com
Study reveals potential Lyme arthritis pathogenesis, treatment
The chemical structure of the Borrelia burgdorferi cell wall may dictate the frequency and severity of Lyme arthritis, a finding that could have implications for future treatment, according to data pu...
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Lyme Disease Biobank @lymebiobank.bsky.social · 12/02/2026
Partnership for new diagnostics for Lyme! Love the shout out to @bstevensonlab.bsky.social - fostering the careers of two great scientists @jutraslab.bsky.social and Jen Miller. Thanks @lymenews.bsky.social for highlighting the importance of collaboration. www.lymedisease.org/galaxy-virgi...
lymedisease.org
Galaxy Diagnostics and Virginia Tech unite in the race for a better Lyme test | LymeDisease.org
Galaxy Diagnostics has entered a new partnership with Virginia Tech to bring Dr. Brandon Jutras’ discovery of Borrelia peptidoglycan into clinical
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Lyme Disease Biobank @lymebiobank.bsky.social · 11/02/2026
Learn more about @bayarealyme.bsky.social new executive director and how the biobank is fueling the research engine.
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Reposted by Lyme Disease Biobank
Brian Stevenson Ph.D. spirochete lab @bstevensonlab.bsky.social · 05/02/2026
The new US budget includes funding for the Tick-Borne Disease Research Program of the CDMRP. Details on the program and requests for applications to be announced soon. cdmrp.health.mil/pubs/press/2... #MicroSky
TBDRP banner, showing:
Gloved hand with blood sample
Three ticks on a human hand
Family walking in the woods
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Lyme Disease Biobank @lymebiobank.bsky.social · 14/01/2026
Check out @bayarealyme.bsky.social Dr. Charlotte Mao's call to action for Lyme research in 2026, building on @hhsofficial.bsky.social roundtable on Lyme. www.bayarealyme.org/blog/a-new-y... #Ticksky #Microsky
bayarealyme.org
A New Year Call to Action After December 15, 2025, HHS Roundtable - Bay Area Lyme Foundation
Bay Area Lyme Spotlight Series By Charlotte Mao, MD, MPH, Bay Area Lyme Foundation “Chronic Lyme Disease patients have been ignored for too long. That must end now.” – Charlotte Mao, MD, MPH A Long-Ov...
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Lyme Disease Biobank @lymebiobank.bsky.social · 08/01/2026
New article highlighting a few of the advances in Lyme disease research. Shout out to @jutraslab.bsky.social for their work! A lot of good research is happening in Lyme - excited for 2026! www.nature.com/articles/d41...
nature.com
Client Challenge
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Lyme Disease Biobank @lymebiobank.bsky.social · 15/12/2025
Today's @hhsofficial.bsky.social Lyme Disease Roundtable is streaming live from 2-4:30pm EST YouTube: youtube.com/live/U3ilMz3... X: x.com/i/broadcasts...
youtube.com
Lyme Disease Roundtable
Secretary Kennedy Convenes Lyme Disease Patients and Providers to Announce New Diagnostic Efforts -- U.S. Department of Health and Human Services (HHS) | http://www.hhs.gov http://www.Twitter.com/H...
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Lyme Disease Biobank @lymebiobank.bsky.social · 26/11/2025
So grateful for Biobank research participants and families who make this resource possible. I'm honored to work with amazing investigators and collaborators working on novel diagnostics for Lyme! We are making progress on this complex disease.
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Lyme Disease Biobank @lymebiobank.bsky.social · 30/10/2025
Check out @lymenews.bsky.social MyLymeData 2025 Research Chartbook! Great graphical representation of registry data and what we are learning from Lyme patients. What an important resource for the community. 10 years of data and counting.
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Lyme Disease Biobank @lymebiobank.bsky.social · 22/10/2025
Funding opp! 2 X 150K awards: 1 on Lyme disease and a new award on tick-borne pathogens (bacterial or parasitic) Academic or private-sector researchers at the post-doctoral through associate professor level (or equivalent) Due: February 15, 2026, at 11:59pm PT www.bayarealyme.org/blog/bay-are...
bayarealyme.org
Bay Area Lyme Foundation Opens Applications for 2026 Emerging Leader Awards and Research Grants - Bay Area Lyme Foundation
FOR IMMEDIATE RELEASE Bay Area Lyme Foundation Opens Applications for 2026 Emerging Leader Awards and Research Grants Annual program to fund two $150,000 grants to revolutionize diagnosis and treatmen...
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Lyme Disease Biobank @lymebiobank.bsky.social · 09/10/2025
This is another single-tier test that I'm really excited about. We require sample users to provide results before we break the blind on the samples. This test from InBio and Kephera's Hybrid ELISA both look really good in early Lyme (~ 1 week) where current serology tests are insensitive.
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Lyme Disease Biobank @lymebiobank.bsky.social · 09/10/2025
New study in @jclinmicroeic.bsky.social shows a new multiplex Lyme serology test is more sensitive than standard two-tier serology tests! Detected more cases w EM at 7 days. Great collaboration with Pete Gwynne @tuftslyme.bsky.social journals.asm.org/doi/10.1128/...
journals.asm.org
The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease | Journal of Clinical Microbiology
During initial Lyme disease infection, existing diagnostic tests have poor sensitivity, resulting in a high number of false-negative tests. This is due to the lag between infection and a robust immune...
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Lyme Disease Biobank @lymebiobank.bsky.social · 21/09/2025
Question for people who frequently publish - I just got a notification that our recent Lyme disease article published in July in Frontiers in Medicine had 500 downloads? Is that good? Thanks! www.frontiersin.org/journals/med...
frontiersin.org
Frontiers | Lyme Disease Biobank: 10 years of 3 month follow-up visits from 2014 to 2023
IntroductionLyme Disease Biobank (LDB) enrolls participants with signs and symptoms of early Lyme disease (LD) from endemic areas and makes samples available...
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Lyme Disease Biobank @lymebiobank.bsky.social · 20/08/2025
I'm really excited about the single-tier assays. There are several in development that have positive results in early Lyme samples with EM that STTT and MTTT miss. These single-tier tests are more sensitive without sacrificing specificity and take less time/resources to run. #TickSky #MicroSky
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Lyme Disease Biobank @lymebiobank.bsky.social · 20/08/2025
Kephera's single-tier Lyme test published in @ASM JCM - Hybrid ELISA approach requires binding to VlsE AND C6. More sensitive in early disease while maintaining specificity. journals.asm.org/doi/10.1128/...
journals.asm.org
A novel single-tier serologic test to diagnose all stages of Lyme disease | Journal of Clinical Microbiology
The diagnosis of Lyme disease, a tick-borne spirochetal infection caused by Borrelia burgdorferi sensu lato, is subject to two major limitations: the need for a two-tier serologic testing algorithm to provide adequate specificity, and the low sensitivity ...
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Lyme Disease Biobank @lymebiobank.bsky.social · 05/08/2025
Article from @medscape.com about LymeSeek - a new Lyme diagnostic in development from Aces Diagnostics plus @bayarealyme.bsky.social biobank data showing how unreliable available tests are in early disease. (They miss 7 out of 10 early Lyme cases) www.medscape.com/viewarticle/...
medscape.com
New Lyme Blood Test Bests Standard Diagnostics
The single-tier test uses artificial intelligence to accurately detect Lyme disease from the first few weeks of infection through 1 year post-diagnosis.
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Lyme Disease Biobank @lymebiobank.bsky.social · 16/07/2025
New research from @gomes-solecki.bsky.social and team on using immunoglobulin class and IgG isotypes to distinguish different stages of Lyme disease. Could help identify early Lyme cases which are often missed by current serology tests. journals.asm.org/doi/10.1128/...
journals.asm.org
Class and isotype of VlsE-specific antibody differentiates Lyme disease stage | Journal of Clinical Microbiology
The order of switching between the immunoglobulin heavy chain (Fc) is time dependent, progressing from IgM/D to IgG3/IgG1/IgA1/IgG2/IgG4 and later to IgE/IgA2. In this study, we show that B. burgdorfe...
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Lyme Disease Biobank @lymebiobank.bsky.social · 15/07/2025
Want to learn more about the biobank? Check out my talk about our sample collection, diagnostics in development using these samples, and finding Borrelia in tissue! Shout out to @livlyme.bsky.social for a great Summit and making these talks available!
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Lyme Disease Biobank @lymebiobank.bsky.social · 13/07/2025
Great interview with @tuftslyme.bsky.social Linden Hu! This really is the year for ticks and Lyme disease.....
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Lyme Disease Biobank @lymebiobank.bsky.social · 20/06/2025
New paper from Jorge Cervantes and team in J Investig Med looking at cytokines in acute and convalescent samples from patients with early acute Lyme. At convalescence, some cytokines returned to normal levels, some were elevated, and others were reduced. journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
EXPRESS: Key inflammatory mediators drive the resolution of acute Lyme disease - Jorge L. Cervantes, Shahrukh Chaudhry, Jose Barragan, Idris Akinlusi, Ted Zhao, Ryan Graff, Bo-young Hong, 2025
Lyme disease is an inflammatory disease in response to Borrelia burgdorferi infection. We analyzed cytokines in sera from acute and convalescent LD patients, an...
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Lyme Disease Biobank @lymebiobank.bsky.social · 12/06/2025
Congratulations! @lymenews.bsky.social MyLymeData is an incredibly important resource in #LymeDisease.
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Lyme Disease Biobank @lymebiobank.bsky.social · 04/06/2025
New study from long time collaborator Neal Woodbury and team at #ASU identifies #biomarkers using #Biobank samples that distinguish #LymeDisease from other febrile illnesses. #diagnostics www.frontiersin.org/journals/imm...
frontiersin.org
Frontiers | Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding
IntroductionLyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the U...
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Lyme Disease Biobank @lymebiobank.bsky.social · 23/05/2025
Read more about Meghan Bradshaw - she is amazing - and she is a scientist.
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Reposted by Lyme Disease Biobank
Lyme Disease Biobank @lymebiobank.bsky.social · 23/04/2025
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
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Reposted by Lyme Disease Biobank
Lyme Disease Biobank @lymebiobank.bsky.social · 28/04/2025
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
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Lyme Disease Biobank @lymebiobank.bsky.social · 29/04/2025
Excited to hear from @jutraslab.bsky.social and @immunofever.bsky.social this Saturday @livlyme.bsky.social. I'm presenting on @bayarealyme.bsky.social Biobank's blood and tissue collection and recently published results. #LymeDisease #MicroSky #TickSky
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Lyme Disease Biobank @lymebiobank.bsky.social · 28/04/2025
Don't miss @livlyme.bsky.social summit on May 3. At 12:45 EST/9:45 PST, I'll be talking about @bayarealyme.bsky.social #LymeDisease #biobank - details on 10 years of collection plus recently published work in diagnostics and pathogenesis. Registration is free #TickSky #MicroSky
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Lyme Disease Biobank @lymebiobank.bsky.social · 23/04/2025
Uh, the other platform is showing me adds about taking a pill to eliminate 99% of parasites from my body. Why??? #Microsky
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Lyme Disease Biobank @lymebiobank.bsky.social · 23/04/2025
Opportunity to tell your Senators and Representative that funding for Lyme and tick-borne disease is important. Letters can be customized! #LymeSky #TickSky app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
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Reposted by Lyme Disease Biobank
Jon Skare Lab @therealjskare.bsky.social · 23/04/2025
app.oneclickpolitics.com/campaign-pag... Urge Congress to protect these critical research programs!
app.oneclickpolitics.com
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
Urge Congress to Protect and Grow Federal Funding for Lyme and Tick-Borne Disease Programs
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Lyme Disease Biobank @lymebiobank.bsky.social · 10/04/2025
Center for Lyme Action launched a campaign to restore funding to CDMRP TBDRP (Tick-borne Disease Research Program). Consider making your voice heard. #TickBsky #MicroBsky app.oneclickpolitics.com/campaign-pag...
app.oneclickpolitics.com
Contact Your U.S. Representative to Restore and Fund DOD’s Tick-borne Disease Research Program
Contact Your U.S. Representative to Restore and Fund DOD’s Tick-borne Disease Research Program
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