A major new centre involving UCL researchers will focus on curing, rather than managing, inflammatory diseases.

Fetuses, neonates, and infants are vulnerable to infectious diseases. At the same time, they are exposed to many harmless antigens; therefore, suppressing

A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.

Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge.

A survey finds that academic supervisors can have a huge impact on their students’ mental health.

Severe pediatric autoimmune diseases (AD) have limited therapeutic options. In a recent issue of Nature Medicine, Becilli et al. report a case series where CD19 CAR T cell treatment of pediatric AD patients induced rapid and durable remissions with manageable toxicity. Notably, patients discontinued standard therapies, and benefits persisted even after B cell reconstitution, highlighting the potential of a reset of the immune system that warrants further exploration.

At WIRED Health, immunologist Daniel Davis detailed the ways in which new technologies are enabling a better understanding of the human immune system.

Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing

Up to 30% of children with juvenile arthritis develop uveitis, an eye inflammation that can damage vision. New research highlights immune cells as treatment targets.