Sign in

jury-lab.bsky.social

@jury-lab.bsky.social
65 followers 64 following 17 posts

Translational research @ucl.ac.uk focusing on lipid metabolism defects in autoimmunity. Special interest in autoimmune rheumatic disease, haemophagocytic lymphohistiocytosis (HLH), cardiovascular risk and immunogenicity

PostsRepliesMedia
Reposted by @jury-lab.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 11/02/2026
It's women and girls in science day! What a great opportunity to highlight the amazing women in our dept.. @dianaematei.bsky.social @clairebeesley.bsky.social @drsianh.bsky.social @jury-lab.bsky.social @ciurtinlab.bsky.social @heather--cross.bsky.social @oliviabracken.bsky.social.
151
Reposted by @jury-lab.bsky.social
Rare Disease Research UK @rdrukhub.bsky.social · 19/12/2025
📣 We’re getting ready to host our 3rd Annual Conference next year and this time, we’re heading to Birmingham! 📅 16 April 2026 📍 The Birmingham Conference & Events Centre, B5 4EW 💯 Save the date and keep an eye out for more updates!
011
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 15/01/2026
🚨New paper from the lab! Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach 📖Read here in Annals of the Rheumatic Diseases: doi.org/10.1016/j.ar... 🙏Huge thank you to all co-authors, funders, and patients!
doi.org
Redirecting
011
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 20/11/2025
Delighted to share our new @natrevrheum.nature.com article: “Insights into the pathogenesis of childhood-onset SLE in the past decade” Grateful to an amazing team of co-authors and editors for building and shaping this work. We hope it helps the field and guides future discoveries.
064
Reposted by @jury-lab.bsky.social
Diana E Matei @dianaematei.bsky.social · 02/12/2025
Now more than usual (since I'm considering applying for a sex-differences based fellowship) I enjoyed and appreciated @ciurtinlab.bsky.social talk #BSI25! We really really need to sex-dissegregate our data!! ♂️♀️
0112
jury-lab.bsky.social @jury-lab.bsky.social · 09/10/2025
So sorry I couldn’t be there to celebrate your amazing achievements @ciurtinlab.bsky.social. Many congratulations
010
Reposted by @jury-lab.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 25/09/2025
Fantastic pictures @georgearobinson.bsky.social and congratulations again @ciurtinlab.bsky.social
041
Reposted by @jury-lab.bsky.social
Bethan Goulden @bethangoulden.bsky.social · 29/07/2025
New systematic review of pregnancy associated HLH - 104 pregnancies - commonest cause infections (EBV, CMV, HSV, parvo) - followed by SLE, stills, lymphoma - 4/14 tested has positive genetics - 40% no known cause onlinelibrary.wiley.com/doi/epdf/10.... 1/6
onlinelibrary.wiley.com
Hemophagocytic Lymphohistiocytosis in Pregnancy: A Systematic Review of Case Reports and Case Series
Aims Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening syndrome caused by excessive immune activation, leading to severe inflammation and multi-organ failure. While adult-onset HL...
174
Reposted by @jury-lab.bsky.social
Bethan Goulden @bethangoulden.bsky.social · 07/07/2025
🤰🤱🩸♀️♂️ ✅UK based Rheumatology healthcare professional? E.g., Consultant, SpR, Nurse, Physio etc working in rheum? Please spend 5 minutes completing our survey mapping access to reproductive services for rheum patients across the UK. Thank you and please share! qualtrics.ucl.ac.uk/jfe/form/SV_...
qualtrics.ucl.ac.uk
Qualtrics Survey | Qualtrics Experience Management
The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.
023
Reposted by @jury-lab.bsky.social
Heather Cross @heather--cross.bsky.social · 11/07/2025
Second talk of the PhD ✅ Thank you so much to the @london-immuno.bsky.social for selecting my abstract on sex hormone/chromosome driven mechanisms of cSLE risk #LIG2025 #LIG25 🧬 🦠 @georgearobinson.bsky.social @ciurtinlab.bsky.social
1153
Reposted by @jury-lab.bsky.social
Lizzy Rosser @bcellsrosser.bsky.social · 18/06/2025
This was a fantastic celebration yesterday - thanks to the @thelisterinstitute.bsky.social and @arrdept-ucldom.bsky.social and the wider division of Medicine for all their support 😊
083
Reposted by @jury-lab.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 20/06/2025
Exciting new position in #arrdept alumni @madhvimenon.bsky.social lab 🧬
021
Reposted by @jury-lab.bsky.social
Medical Research UK @medicalresearchuk.bsky.social · 14/04/2025
💉 Antiphospholipid Syndrome (#APS) is an autoimmune disorder that requires our urgent attention. 🔬 Thanks to your support, we've been able to fund researchers like Dr Thomas McDonnell. His ground-breaking work is advancing our understanding of APS, paving the way for better treatments.
164
Reposted by @jury-lab.bsky.social
Autoimmune🦋 @autoimmuneaware.bsky.social · 06/02/2025
Hemophagocytic Lymphohistiocytosis 🔹Life-threatening syndrome of overwhelming inflammation 🔹Is crucial to search and treat the underlying trigger 🚩Fever, #Splenomegaly, #Cytopenia, #hyperferritinemia, #hypertriglyceridemia, bone marrow #hemophagocytosis #HLH @nejm.org www.nejm.org/doi/pdf/10.1...
nejm.org
Hemophagocytic Lymphohistiocytosis | NEJM
HLH, a cytokine-mediated hyperinflammation syndrome, causes fever, pancytopenia, and hemophagocytosis and is often fatal. Antiinflammatory agents, etoposide, and interferon-γ antibody are the main ...
131
Reposted by @jury-lab.bsky.social
Heather Cross @heather--cross.bsky.social · 15/06/2025
Thank you so much! 😁 #EULAR2025 was an amazing first conference talk and I am so pleased and grateful to have been featured in the highlights as well!
0113
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 14/06/2025
Nailed it! 👏
021
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 19/06/2025
It's official! Congratulations to everyone selected for the International Union of Immunological Societies (IUIS) #RisingStars2025 Cohort! I can't wait to meet you all at #IUIS2025 and share our research! Thank you to @iuis-online.bsky.social and @britsocimm.bsky.social for the nomination @ucl.ac.uk
061
Reposted by @jury-lab.bsky.social
Journal of Experimental Medicine @jem.org · 26/06/2025
@simonyona.bsky.social et al show that quantify the ephemeral circulating lifespan of human cDC & propose functions of cDC & their precursors that are rapidly recruited to sites of #inflammation rupress.org/jem/article/... 📘 In Clinical #Immunology Collection: rupress.org/jem/collecti... #FOCIS2025
163
Reposted by @jury-lab.bsky.social
@taamslab @taamslab.bsky.social · 18/06/2025
I feel incredibly honoured and privileged to receive this award and recognition. I ♥️ the @britsocimm.bsky.social. If you're not yet a BSI member, do sign up and become part of this amazing and supportive community, with an excellent #researchculture
1164
Reposted by @jury-lab.bsky.social
Seth Thomas Scanlon @immunoeditor.bsky.social · 18/06/2025
This month in #Science #Immunology, Shivangi Dave & André Ballesteros Tato at the #NIH review the noncanonical contributions of #TFollicularHelper ( #TFH ) cells cells to immune regulation beyond their traditional roles in #BCell help! science.org/doi/10.1126/sciimmunol.adr1052
Conventional and nonconventional functions of TFH cells: In addition to their conventional role as GC facilitators—providing survival and proliferation signals to GC B cells—TFH cells also perform noncanonical functions. They can support CD8+ T cell responses, produce effector-like cytokines that critically influence B cell fate decisions beyond GC maintenance, and exhibit TSCM properties that allow them to serve as reservoirs for pathogenic Teff cell subsets across various anatomical niches
0277
Reposted by @jury-lab.bsky.social
MacDonald Obstetric Medicine Society @moms.org.uk · 18/06/2025
🩺 Prof. Catherine Aiken sharing key insights from the MBRRACE reports on cancer in pregnancy. 📊 1 in 4,000 women is diagnosed with a new cancer during pregnancy. For most maternity units, that’s ~1–2 cases per year. #MaternalHealth #Oncology
112
Reposted by @jury-lab.bsky.social
Adlung Lab @adlunglab.com · 18/06/2025
🧠 IFNγ alters the immuno-/proteasome, thus glycolysis surges, oxidation rises, and axons die in models of MS. Blocking the proteasome swap or glycolysis saves nerves. Impressive work by our esteemed colleague @manuelfriese.bsky.social in @cp-cell.bsky.social‬: doi.org/10.1016/j.ce... 🧪‪
doi.org
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis
Inflammation, aberrant proteostasis, and energy depletion are hallmarks of neurodegenerative diseases such as multiple sclerosis (MS). However, the in…
062
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 09/06/2025
It’s #EULAR2025 week! 🌟 We’ve got a EULAR sandwich 🥪 this year with me presenting on type I interferon signalling in cSLE on Wednesday afternoon (4.30-6pm, room 6.4), then @heather--cross.bsky.social presenting on sex hormones and cSLE risk on Saturday (12-1.15pm, room A1) See you in Barcelona! 🇪🇸
182
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 11/06/2025
Made it! #EULAR2025 I’m looking forward to presenting later today on a novel approach to investigating type I interferon signalling in cSLE. Interrogating different signalling levels gives unique pieces of information and new disease endotypes. Hopefully see you there to hear more!
152
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 12/06/2025
Inspiring talk from the amazing Jess Manson! 🙌 @jury-lab.bsky.social
031
Reposted by @jury-lab.bsky.social
The European Alliance of Associations for Rheumatology @eular.org · 27/05/2025
👋Welcome from the PAED Community. Join us at #EULAR2025 in Barcelona! Discover breakthroughs in: ✨Still’s disease in children & adults. 🌍Global care for Juvenile Idiopathic Arthritis. 🎓Managing childhood lupus. Learn more 👉 pulse.ly/r8vog3jfnx #eularPAED #Rheumatology
054
jury-lab.bsky.social @jury-lab.bsky.social · 11/06/2025
Posters all about our #HLH research on now #EULAR @arrdept-ucldom.bsky.social
054
Reposted by @jury-lab.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 28/05/2025
It's time for our next ARR dept research spotlight💡with 1st year PhD student @heather--cross.bsky.social! Heather is working in @georgearobinson.bsky.social's lab with @ciurtinlab.bsky.social to uncover the impact of sex and gender ⚧️ on metabolism and its relevance to autoimmune conditions💥
153
jury-lab.bsky.social @jury-lab.bsky.social · 06/06/2025
That looks worrying!!
010
jury-lab.bsky.social @jury-lab.bsky.social · 06/06/2025
Enjoy #EULAR @heather--cross.bsky.social great opportunity to present your exciting work on sex hormones and immunity
050
jury-lab.bsky.social @jury-lab.bsky.social · 06/06/2025
Congratulations @georgearobinson.bsky.social well deserved
110
Reposted by @jury-lab.bsky.social
ImmuNinjas @immuninjas.bsky.social · 29/05/2025
We got an upgrade!!💥
012
jury-lab.bsky.social @jury-lab.bsky.social · 06/06/2025
Such a pleasure to collaborate with @ciurtinlab.bsky.social - she is a an amazing clinician and scientist - looking forward to submitting on our next research manuscript soon.....watch this space!!
010
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 05/06/2025
Great to have the reminder of how exciting this department is. So much great science and so much potential for more! @arrdept-ucldom.bsky.social
052
Reposted by @jury-lab.bsky.social
British Society for Immunology @britsocimm.bsky.social · 21/05/2025
An unforgettable evening awaits on 18 June at 18:30 BST! 🍾 We would love for you to join us in celebrating groundbreaking achievements in #immunology at the BSI Immunology Awards in London. Don’t miss out - secure your FREE ticket today! 👉 bit.ly/43veEGr
011
Reposted by @jury-lab.bsky.social
Lizzy Rosser @bcellsrosser.bsky.social · 15/05/2025
🏆
051
jury-lab.bsky.social @jury-lab.bsky.social · 15/05/2025
Next up is @georgearobinson.bsky.social showing his latest data stratifying young patients with childhood onset SLE using molecular profiles
053
Reposted by @jury-lab.bsky.social
UCL Dept of Aging, Rheumatology & Regenerative Medicine @arrdept-ucldom.bsky.social · 14/05/2025
It’s time for our next researcher highlight which is @junjie-peng.bsky.social a postdoc in the @ciurtinlab.bsky.social 🙌🏽 Junjie is a data scientist 🧑‍💻 applying machine learning & advanced analytical approaches to multi-omics data aiming to improve stratification of rheumatic disease patients 🧬
164
Reposted by @jury-lab.bsky.social
George Robinson @georgearobinson.bsky.social · 15/05/2025
👇👇👇 🎉
021
Reposted by @jury-lab.bsky.social
Scott Canna @cannalab.bsky.social · 14/05/2025
Histiocyte Society #HLH Webinar "Multi-disciplinary Approach to Managing HLH" Headlined by @racheltattersall.bsky.social and Jessica Manson, @ucl.ac.uk who've really brought HLH excellences to @england.nhs.uk July 24th, 11AM NY/8AM SF/4PM UK/5PM CET Details and link are forthcoming
055
Reposted by @jury-lab.bsky.social
London Immunology Group @london-immuno.bsky.social · 14/05/2025
We're thrilled to see members of our team shortlisted for the 2025 #BSIAwards 🏆for their active role in driving & inspiring change in the #immunology field🤩 @pallettlab.bsky.social is nominated for: BSI Diversity & Inclusion Award & our ECRs are nominated for: Outstanding Team Award Congrats! 👏
273
Reposted by @jury-lab.bsky.social
Women As One @womenasone.bsky.social · 10/05/2025
💜 On #WorldLupusDay, let’s raise awareness: Women aged 35-44 with lupus are 50x more likely to have a heart attack than those without. Shout-out to the women advancing research on lupus & heart health: 👇 @virusesimmunity.bsky.social @inespinedatorra.bsky.social #CardioSky #MedSky
Headshots of the five physicians we are highlighting for World Lupus Day. Anne Troldborg, MD, PhD, Elizabeth Jury, PhD, Inés Pineda-Torra, PhD, Akiko Iwasaki, PhD and Ruth McPherson, MD, PhD, FRCPC.
26818
jury-lab.bsky.social @jury-lab.bsky.social · 09/05/2025
Really interesting work- congratulations. Take a look @mcdonnelllab.bsky.social @georgearobinson.bsky.social
010
Reposted by @jury-lab.bsky.social
Sarah Dimeloe @sarahdimeloe.bsky.social · 20/01/2025
Many thanks to all our collaborators for their support with this project. The RNA-seq data we analysed from patients who had received auto-SCT were originally published in the paper below where you’ll find further analysis and context www.cell.com/iscience/ful...
cell.com
Lymphopenia-induced lymphoproliferation drives activation of naive T cells and expansion of regulatory populations
Immunology; Cell Biology
021
Reposted by @jury-lab.bsky.social
ciurtinlab.bsky.social @ciurtinlab.bsky.social · 30/04/2025
Great evening at the Royal College for #ActionMedicalResearch fundraising reception talking about our research on #cardiovascular risk in #juvenilelupus. @arrdept-ucldom.bsky.social; @junjie-peng.bsky.social; @georgearobinson.bsky.social; @jury-lab.bsky.social
055
Reposted by @jury-lab.bsky.social
Diana E Matei @dianaematei.bsky.social · 24/04/2025
go.bsky.app/NExREdt Happy to be part of such a great department! Follow us to learn more about what we're about 😁🙌
043
Reposted by @jury-lab.bsky.social
Matthias Eberl @eberlmat.bsky.social · 20/04/2025
Vaccines work… and do not cause autism. "The best vaccine isn’t useful if it is not distributed, or not socially accepted. Vaccine equity and hesitancy remain great challenges that we ignore at our peril." #CelebrateVaccines @plosbiology.org @npariente.bsky.social
journals.plos.org
Vaccines work… and do not cause autism
Vaccines have saved millions of lives, yet their importance and safety is repeatedly in question. W e cannot let disinformation campaigns get in the way of global public health – it is not time to def...
04715
Reposted by @jury-lab.bsky.social
ACR Journals @acr-journals.bsky.social · 21/04/2025
Mixed methods study of 21 patients w/ childhood-onset lupus explored resilience across individual & socioecologic domains, identifying 5 themes: familial environment, social support beyond family, health services & info, life with SLE, sense of self AC&R doi.org/10.1002/acr.... #Medsky #Rheumsky
Individual Patient Profiles of Socioecological Resilience: Distribution of Qualitative Themes for Barriers and Facilitators Across the Spectrum of Resilience Scores
Shown are individual patient profiles (each represented by a horizontal bar, n=21), plotted according to their socio-ecological resilience scores as measured vy the CYRM-R scale. Each patient profile shows the number of barriers (negative numbers) and facilitators (positive numbers) of resilience, as reported in qualitative interviews, color-coded by theme. The cohort is grouped according to low vs high socio ecological resilience on the CYRM-R measure. Patients with resilience scores at or below the median score of 73 (indicated by dotted line) were attributed a low resilience profile, and patients with scores higher than 73 were attributed a high resilience profile
033
Reposted by @jury-lab.bsky.social
Nature Methods @natmethods.nature.com · 21/04/2025
scMultiSim is a comprehensive single-cell and spatial data simulator generating realistic multi-omics data based on modeling gene regulatory networks, cell-cell interactions, and other biological and technical factors. www.nature.com/articles/s41...
073
jury-lab.bsky.social @jury-lab.bsky.social · 10/04/2025
After a bit of a break it was great to meet with @inespinedatorra.bsky.social and her team working on cardiovascular risk in women pre and post menopause. Next time it’s the turn of @georgearobinson.bsky.social @heather--cross.bsky.social to present.
140