iiinova — where your digital self keeps evolving

Ashraful Haque @assocprofashhaque.bsky.social · 02/09/2025

Welcome all to Pentridge Prison, Melbourne, for the Melbourne Immunotherapy Network Spring Symposium. Get your mugshot taken, and hear about the local translational immuno-landscape! www.melbourneimmunotherapy.org

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Ashraful Haque @assocprofashhaque.bsky.social · 19/06/2025

Here's an updated poster for the Melbourne Immunotherapy Network, Spring Symposium & Dinner. For details and registration, please visit this link: www.melbourneimmunotherapy.org Please re-post

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Ashraful Haque @assocprofashhaque.bsky.social · 14/06/2025

Allegedly, a dozen eggs may soon cost $250 in Melbourne. Dear students of immunology & immunotherapy, spend your $ instead on the Melbourne Immunotherapy Network Symposium & Dinner (2-3 Sept, Pentridge Prison). You can translate without breaking eggs! www.melbourneimmunotherapy.org

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Mauro Gaya @maurogaya.bsky.social · 30/04/2025

🚨🦠🔬 Last month to register to the EMBO workshop on Adaptive Immunity in Barrier Tissues. 📍 Where: Basel, Switzerland 📅 When: 26th–29th August 2025 📝 Registration deadline: 30th May 2025 Childcare support & travel grants from @embo.org and @efis-immunology.bsky.social #EMBOBarrierTissues

meetings.embo.org

Adaptive immunity in barrier tissues

Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

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Ashraful Haque @assocprofashhaque.bsky.social · 15/05/2025

Pls re-post: Melbourne Immunotherapy Network Spring Symposium, 2-3 Sept 2025, at Pentridge Prison (No current inmates BTW). www.melbourneimmunotherapy.org $250 for students (inc. networking drinks, conference dinner in prison hall, and after-dinner speaker - to be announced soon). C U behind bars!

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Ashraful Haque @assocprofashhaque.bsky.social · 09/04/2025

Ever wondered what the immune system looks like up close? With a technique called Spatial Transcriptomics, we detected ~20,000 genes in the spleen, and converted the data into a zoom-able interactive app with DEPT IT agency, to inform school kids etc about immune cells & health. Do you like it?

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Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 28/03/2025

Yes. The situation at NIH is worse than the public realizes. The #NIH is on track to be effectively ended as a funder of evidence-based research within a year. That is not an exaggeration. The firings and consolidation announced today will create a new, MUCH worse NIH. 1/

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Gabriel Victora @victora.bsky.social · 19/03/2025

Cool germinal center acrobatics from Juhee Pae et al, check it out! www.nature.com/articles/s41...

nature.com

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Human Cell Atlas @humancellatlas.org · 20/03/2025

HCA scientists have assembled the Asian Immune Diversity Atlas (AIDA), the world’s first multi-national survey of human blood at single-cell resolution, providing insights into human variation, biological mechanisms, disease risk, and diagnostic criteria.

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Ashraful Haque @assocprofashhaque.bsky.social · 20/03/2025

Saba Asad had to deal with COVID lockdowns, home schooling her kids, a tough mouse breeding program and more; yet 3 years later her PhD Oration on B cell scRNAseq in malaria was fab! Well done, Saba. Good luck with thesis submission. Read her pre-print work here: www.biorxiv.org/content/10.1...

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Radiohead @radiohead.wastehq.social · 14/03/2025

We found this VHS tape of Thom performing at the Horseshoe Tavern, Toronto in 1995 for the release of The Bends Watch the full show waste.lnk.to/horseshoetav...

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Ashraful Haque @assocprofashhaque.bsky.social · 11/03/2025

Register TODAY: Melbourne Immunotherapy Network, 2-day Spring Symposium, Pentridge Prison, Coburg! 2-3 Sept '25. Student Early Bird: $250, inc. conference dinner (No metal prison trays, I promise!) Click below to register and submit your Abstract. www.melbourneimmunotherapy.org/registration

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British Society for Immunology @britsocimm.bsky.social · 04/03/2025

Get ready for #WorldImmunologyDay2025! 🌎 Join us at The Francis Crick Institute on 24 April to explore "The immune system and your brain" 🧠 Hosted by @claudiahammond.bsky.social and run by @britsocimm.bsky.social, @natureportfolio.nature.com and @crick.ac.uk Register for FREE now: bit.ly/41m8kP9

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Ashraful Haque @assocprofashhaque.bsky.social · 03/03/2025

Here's a new co-authored pre-print with Michelle Boyle @burnetinstitute.bsky.social, studying cTfh cells in volunteers infected with P. falciparum, via scRNA-seq and paired TCR-seq. Tfh1 are split based on CCR7, with CCR7+ Tfh1 correlating with antibody responses. www.biorxiv.org/content/10.1...

biorxiv.org

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theasmr.bsky.social @theasmr.bsky.social · 02/03/2025

The ASMR is delighted to announce the appointment of Dr Shane Huntington OAM (@drshanerrr.bsky.social) as the society’s inaugural CEO. Shane brings extensive experience in leadership, research, communication and engagement. He is the ideal appointment to guide the expansion and impact of ASMR.

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Ashraful Haque @assocprofashhaque.bsky.social · 28/02/2025

Just a quick reminder from Roald Dahl in 1962. Vaccination protects against measles…..

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E John Wherry @ejohnwherry.bsky.social · 26/02/2025

First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork

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Ashraful Haque @assocprofashhaque.bsky.social · 25/02/2025

@keystonesymposia.bsky.social Our Melbourne team is v sad not to be at the Keystone B cell meeting, Monaco, but will watch the On Demand versions at lab meetings! I hope to present our study on temporal dynamics of CSR, expansion, fate & SHM in 2026. read it here www.biorxiv.org/content/10.1...

biorxiv.org

Temporally overlapping mechanisms diversify clonal B cell responses in vivo

Single naive B cells amplify and diversify their responses when activated by cognate antigen, via Myc-dependent clonal expansion, immunoglobulin class switch recombination (CSR), phenotypic variation,...

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Prof Sheena Cruickshank @sheencr.bsky.social · 19/02/2025

This is a REALLY important thread about the threat to vaccine, vaccine access and vaccine design the new administration is. Do read

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Ashraful Haque @assocprofashhaque.bsky.social · 18/02/2025

An exciting day at @thedohertyinst.bsky.social today, since we welcome our 2025 cohort of Honours students at the Department of Microbiology & Immunology. It’s going to be a rewarding year for all concerned!

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ex-Lethality Jane @lethalityjane.bsky.social · 15/02/2025

The measles outbreak in Texas is reminding me of the public letter Roald Dahl wrote about losing his daughter to measles in 1962, just before the vaccine was publicly available.

Excerpt from a public letter Roald Dahl wrote encouraging people to vaccinate their children.

Olivia, my eldest daughter, caught measles when she was seven years old. As the illness took its usual course I can remember reading to her often in bed and not feeling particularly alarmed about it. Then one morning, when she was well on the road to recovery, I was sitting on her bed showing her how to fashion little animals out of coloured pipe-cleaners, and when it came to her turn to make one herself, I noticed that her fingers and her mind were not working together and she couldn’t do anything.

“Are you feeling all right?” I asked her.

“I feel all sleepy,” she said.

In an hour, she was unconscious. In twelve hours she was dead.

The measles had turned into a terrible thing called measles encephalitis and there was nothing the doctors could do to save her. That was twenty-four years ago in 1962, but even now, if a child with measles happens to develop the same deadly reaction from measles as Olivia did, there would still be nothing the doctors could do to help her.

On the other hand, there is today something that parents can do to make sure that this sort of tragedy does not happen to a child of theirs. They can insist that their child is immunized against measles. I was unable to do that for Olivia in 1962 because in those days a reliable measles vaccine had not been discovered. Today a good and safe vaccine is available to every family and all you have to do is to ask your doctor to administer it.

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Ashraful Haque @assocprofashhaque.bsky.social · 03/02/2025

If you're interested in vaccines, cancer immunotherapy, blocking autoimmune disease, early detection of disease etc, check out the Melbourne Immunotherapy Network: www.melbourneimmunotherapy.org/background Here are our supporting institutions below. Come along to our September meeting in Melbourne.

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Ashraful Haque @assocprofashhaque.bsky.social · 03/02/2025

This may be the 1st Immunotherapy Meeting to be held in a PRISON! We will discuss how scientific discoveries can be best developed to detect, treat, and prevent human diseases for which the immune system is either the cause or a potential cure. Registration opens soon: www.melbourneimmunotherapy.org

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Steve Turner @sjturn.bsky.social · 30/01/2025

Also, the submission and editorial experience with @immunolcellbiol.bsky.social was fantastic, highly efficient, very professional, and yes I am an #AusNZSocImmunol member, but if you are looking for somewhere to publish #immunologyiscool work, can't recommend highly enough.

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Shalin H. Naik @shalinhnaik.bsky.social · 30/01/2025

@ozsinglecell.bsky.social #OzSingleCell25 has a new website www.ozsinglecell.com See the current list of invited speakers and stay tuned for registration details. Sponsors reach out to ozsinglecells@gmail.com

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Mucosal Immunology @mucosalimmunol.bsky.social · 27/01/2025

Follow our new podcast for more Mucosal Immunology - #MucosalMondays, coming to you the last Monday of every month.

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Ashraful Haque @assocprofashhaque.bsky.social · 26/01/2025

A taste of 2025: In a B-cell scRNA-seq pre-print, we temporally map B cell activation processes in the spleen during malaria, inc. class-switch recombination, proliferation, somatic hypermutation and bystander activation. Click below, and let me know your thoughts!! www.biorxiv.org/content/10.1...

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Ashraful Haque @assocprofashhaque.bsky.social · 26/01/2025

Also in mid-2024, we used Spatial Transcriptomics (Slide-seqv2) with Fei Chen at @broadinstitute.org to study CD4+ T cell differentiation in malaria. You can mine the data here: haquelab.mdhs.unimelb.edu.au/spatial_gui/ You can read the Cell Reports paper for FREE here: www.cell.com/cell-reports...

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Ashraful Haque @assocprofashhaque.bsky.social · 26/01/2025

In mid-2024, we mapped the in vivo recall responses of splenic CD4+ T cells during blood-stage re-infection with malaria parasites. You can mine the data for yourself here: haquelab.mdhs.unimelb.edu.au/cd4_re-infec... You can read the Nature Comms paper for free here: www.nature.com/articles/s41...

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Ashraful Haque @assocprofashhaque.bsky.social · 26/01/2025

As an introduction to Bluesky, I'll summarise a few of our recent studies. In mid-2023, we used scRNA-seq of malaria parasites directly ex vivo to discover that trophozoite stages uniquely slowed their maturation when experiencing systemic inflammation in the host. journals.asm.org/doi/epdf/10....

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John Tregoning @prof-tregoning.bsky.social · 09/01/2025

My book is out today - buy it (please)

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