iiinova — where your digital self keeps evolving

Matt Loose @minomatt.bsky.social · 16/07/2026

Missing having the ability to look at nanopore runs from your iOS device? I do and so we’ve had a play building on @nanoporetech.com minknow api. If you want to test CodPilot you can here. testflight.apple.com/join/DgMNMY1A

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Matt Loose @minomatt.bsky.social · 13/07/2026

UK Genome Science - early bird deadline is getting close… and you know what they say about the early bird. Not sure what that really has to do with it, but if you want to come along please do register.

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Matt Loose @minomatt.bsky.social · 02/07/2026

A great lesson in life is to be more like Mike Hubank (one of the nicest out of many nice people in Genomics!) - but on this specific occasion we should all be more like Mike and book our tickets for UK Genome Science - see www.genomescience.org.uk for more details.

genomescience.org.uk

Genome Science UK 2026

Manchester University

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Matt Loose @minomatt.bsky.social · 02/07/2026

Hey everyone - I don’t post often now - but don’t forget about the fabulous UK Genome Science meeting being held in Manchester this year from the 14th-16th September. Early bird registration closes at the end of July. Info here - www.genomescience.org.uk

genomescience.org.uk

Genome Science UK 2026

Manchester University

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Josh Quick @scalene.bsky.social · 22/05/2026

New preprint from us! 🦠 Clinical metagenomics is great for sequencing pathogens directly from patient samples but for some protocols sensitivity for RNA viruses lags behind bacteria & fungi. We have shown why, and how to fix it. www.medrxiv.org/content/10.6...

medrxiv.org

Library preparation strategy critically impacts RNA virus sensitivity in clinical metagenomics

Clinical metagenomics uses sequencing for culture-independent identification of pathogens directly from clinical specimens. While a number of protocols claim to be pathogen agnostic, sensitivity for R...

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Matt Loose @minomatt.bsky.social · 20/05/2026

Very cool to see noise cancelling headphones for adaptive sampling #nanoporeconf

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Matt Loose @minomatt.bsky.social · 30/04/2026

@cshlpress.bsky.social something wrong with the CSHL alerts emails? It seems to be sending random email notifications to people?

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Matt Loose @minomatt.bsky.social · 10/11/2025

Very interesting day at the genomics England long read summit. And great to catch up with @generoom.bsky.social and more!

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Matt Loose @minomatt.bsky.social · 10/11/2025

Very nice summary of a number of cohorts and chemistries across @nanoporetech.com from genomics England.

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Matt Loose @minomatt.bsky.social · 07/10/2025

Spent the last hour helping solve quadratic equations for my son’s maths homework. I knew my A-level maths would one day come in useful. And it has. To do his A-level maths.

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Matt Loose @minomatt.bsky.social · 25/09/2025

PhD opportunity available on epigenomics/trasncriptomics as part of the network of clinicians and researchers working in glioblastoma research at @uniofnottingham.bsky.social Using a wide range of tech and methods but definitely long reads @nanoporetech.com - more at lnkd.in/eBtrtZiM

lnkd.in

This link will take you to a page that’s not on LinkedIn

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Nick Loman @pathogenomenick.bsky.social · 22/09/2025

A bit like spiralling publication costs we need to start having a proper discussion around lab equipment servicing costs. These are often completely disproportionate to the cost of instrument and the service that is provided and seem to serve as a cash cow for vendors.

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Matt Loose @minomatt.bsky.social · 19/08/2025

Great to see this paper out www.nature.com/articles/s41... including Chris Moore of the Nottingham DeepSeq team. Chris took @nanoporetech.com Mk1Cs out to Columbia and sequenced chocolate. Coverage www.theguardian.com/science/2025... and institutions.newscientist.com/article/2492....

theguardian.com

Scientists claim to have unlocked ‘secret sauce’ needed for fine chocolate

Results of studying cocoa bean fermentation in Colombia could pave way to manipulate flavour, say researchers

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Matt Loose @minomatt.bsky.social · 17/07/2025

For @nanoporetech.com geeks I’ve just been pointed at this very helpful site - nanoporetech.github.io/ont-output-s... - I hadn't seen this before and it's very useful!

nanoporetech.github.io

Oxford Nanopore Output Specifications

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Matt Loose @minomatt.bsky.social · 09/05/2025

UK Genome Science meeting - Newcastle. 9th - 11th July 2025. Great speakers. Great community. Early bird registration-16th May Abstract submission-23rd May Registration close-26th June If you want that sweet sweet early bird deal - get going quick! www.genomescience.org.uk

genomescience.org.uk

Genome Science UK 2025

Newcastle University

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Matt Loose @minomatt.bsky.social · 08/05/2025

RIP MK1B. You always punched way beyond your weight. @nanoporetech.com about that mk1D…

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pore-xy.bsky.social @pore-xy.bsky.social · 11/04/2025

Faster Brain Tumour classification now being validated in Sydney @lavsat.bsky.social based on the work of @minomatt.bsky.social and collaborators youtu.be/sfykXrvSs28

youtu.be

New device that can detect tumours within 24 hours | 9 News Australia

YouTube video by 9 News Australia

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Matt Loose @minomatt.bsky.social · 28/03/2025

UK Genome Science 2025 is going live for this year - www.genomescience.org.uk - get registering!

genomescience.org.uk

Genome Science

9th - 11th July 2025, Newcastle University

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Matt Loose @minomatt.bsky.social · 22/03/2025

A benefit of being on the other side of the world is being able to watch the sprint race live.

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Matt Loose @minomatt.bsky.social · 19/03/2025

Real pleasure to be presenting at the @nanoporetech.com #WYMM event in Melbourne Australia today. Great to see the pores work equally well upside down. And at last - socks! Though I still think they should be the long sock… youtu.be/zxI-pcLj9XE?...

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Matt Loose @minomatt.bsky.social · 18/03/2025

Just wish I knew what the actual question was… “FASTA, FASTQ and FAST5…” - fill in the blanks?

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Matt Loose @minomatt.bsky.social · 05/03/2025

Great to be visiting @nanoporetech.com as part of a cns Nanopore symposium meeting with pathologists and clinical scientists to discuss the application of nanopore sequencing in the clinic.

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Matt Parker @bioinfomatt.bsky.social · 27/02/2025

#AGBT2025 #AGBTGM has been incredible. Lucky to be part of the event with @nanoporetech.com - as always we were so looked after by our amazing events team! (Photo credit to @minomatt.bsky.social)

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Jonathan Coxhead @4130chromo.bsky.social · 30/01/2025

Well done @fogenomics.bsky.social another fantastic meeting ✨ Caught up with so many friends 🙏 Great speakers and even better networking 🧬🧬 #FOG2025 See you all in July at Genome Science, in Newcastle 🥳

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Matt Loose @minomatt.bsky.social · 28/01/2025

For info - it’s DeepSeq for all your next generation sequencing needs. Deep Seek will do something completely different…

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Matt Loose @minomatt.bsky.social · 28/01/2025

They said I’d be able to check my accounts more quickly… everything would be simpler. 15 minutes later - I still can’t see how much money is in my account. Could someone at a university tell me that this system gets better over time? Because so far… it’s exactly as bad as people said it would be.

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Matt Loose @minomatt.bsky.social · 01/01/2025

Fun to see some killer whale poo seq on #bbc2 today using @nanoporetech.com Still want to get a whale read from a whale one day!

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Matt Loose @minomatt.bsky.social · 24/12/2024

Well - this is awkward. According to santatracker.google.com Santa is on his way. But according to Norad www.noradsanta.org/en/map he’s going to take off shortly. Something up with norad?

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Matt Loose @minomatt.bsky.social · 18/12/2024

And so we reach the glorious time of year where authors try to push papers to editors to “get them off the desk” whilst editors try to clear their desks for the break. Referees try to rapidly return reports to editors and nothing will happen to anything for a good 10 days…

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Matt Loose @minomatt.bsky.social · 12/12/2024

Nottingham Nanopore contingent out to celebrate Dr Munro

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Matt Loose @minomatt.bsky.social · 04/12/2024

Does cold emailing academics with information on commercial services or products actually work? I find academics very rarely respond to emails let alone cold ones. The worst are the ones that try and guilt trip you into responding…

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Matt Loose @minomatt.bsky.social · 28/11/2024

This is worth looking at. Trying some genomes we have assembled with earlier versions of hifiasm, hifiasm plus herro and then this new version of hifiasm. The early assembly results suggest that now hifiasm alone is equivalent to what we got with herro but with less compute!

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Matt Loose @minomatt.bsky.social · 23/11/2024

Saturday. Saturday. Saturday. Saturday. Saturday.

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Matt Loose @minomatt.bsky.social · 22/11/2024

Its interesting to see my PhD students slow and dawning realization that the hardest thing he will ever have to do is submit his data to an online open database…

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Matt Loose @minomatt.bsky.social · 21/11/2024

Given that this place has become a little busier in recent days I’m reposting this. We’re doing a lot of work in this tool at present and it’s great to be working so closely with Nottingham university hospitals.

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Matt Loose @minomatt.bsky.social · 15/11/2024

It’s Friday evening. Any banter happening anywhere?

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Nick Loman @pathogenomenick.bsky.social · 11/11/2024

After editing, this very short letter to New Scientist is even shorter now. But I think it gets the point across! @faecalmatters.bsky.social

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Matt Loose @minomatt.bsky.social · 12/11/2024

Lots been going on in the last few days. Plenty to process and think about.

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Matt Loose @minomatt.bsky.social · 09/11/2024

Bluesky really seems to be taking off in the last few days. Did something happen?

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Matt Loose @minomatt.bsky.social · 08/11/2024

Looks like this place is filling up.

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Matt Loose @minomatt.bsky.social · 16/09/2024

Introducing ROBIN. Rapid nanopOre Brain intraoperatIve classificatioN. ROBIN builds on work by many groups and shows how we could reduce turnaround time for full molecular classification of CNS tumours in NHS clinical settings from weeks to hours. www.medrxiv.org/content/10.1...

medrxiv.org

ROBIN: A unified nanopore-based sequencing assay integrating real-time, intraoperative methylome classification and next-day comprehensive molecular brain tumour profiling for ultra-rapid tumour diagn...

medRxiv - The Preprint Server for Health Sciences

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Matt Loose @minomatt.bsky.social · 18/10/2024

Is there more happening here now?

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Matt Loose @minomatt.bsky.social · 16/09/2024

medrxiv.org

medRxiv - The Preprint Server for Health Sciences

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Nic @nicolalala.bsky.social · 19/07/2024

Martin’s on a plane with a Danish guy dressed as Darth Vader en route to the US. Unfortunately due to the IT outage his case wasn’t loaded on the plane. Thoughts and prayers to that dude.

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Matt Loose @minomatt.bsky.social · 19/07/2024

Old @pathogenomenick.bsky.social told me that blue sky is the place to be so I thought I’d see if that is true again.

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Matt Loose @minomatt.bsky.social · 08/05/2024

We are holding an event on Thu 27 Jun 10:00 AM - 5:00 PM: CNS Rapid Diagnostics Information Day - this will cover our research only use of nanopore technology in looking at tumours. The meeting is in person and requires registration, but is free to attend. buytickets.at/cnstumourdia...

buytickets.at

CNS Rapid Diagnostics Information Day – Medical School, Queens Medical Centre, Thu 27 Jun 2024 - The University of Nottingham and Nottingham University Hospitals NHS Trust will be hosting a training a...

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