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Andrew Holding

@andrewholding.bsky.social
3.1K followers 868 following 302 posts

Academic. Scientist. Father. Breast Cancer Researcher. Sometimes on TV/Radio.

PostsRepliesMedia
Andrew Holding @andrewholding.bsky.social · 07/08/2025
Excited to share that the Expression of Interest form is open for the UKYA Health OpenSpaces: Pregnancy in research event on 15 Sep 2025! Details in thread. 🔗 ukyoungacademy.org/events/healt... #PregnancyResearch #HealthEquity #MedicalResearch #PublicInvolvement #DiverseVoices #UKYA 🧪 1/3
ukyoungacademy.org
Health OpenSpaces | Pregnancy in research | UK Young Academy
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Andrew Holding @andrewholding.bsky.social · 03/07/2025
Come join us! Great community and in a great location. Transcription and Chromatin Uk from @biochemsoc.bsky.social
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Andrew Holding @andrewholding.bsky.social · 07/05/2025
Still time to sign up for this talk tomorrow. Professor Alana Welm will be talking her work developing patient derived models for cancer therapy.
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Andrew Holding @andrewholding.bsky.social · 24/04/2025
YBRI (@ybri-uoy.bsky.social) are hosting @alanawelm.bsky.social for an online seminar on 9th May 2pm BST. Prof Welm will be presenting her work on "Modeling metastatic breast cancer to advance therapeutic strategies". Please share, and register to join at www.eventbrite.co.uk/e/ybri-onlin...
eventbrite.co.uk
YBRI Online Biomedical Sciences Seminar 2025
Join our online biomedical sciences seminar open to UG, PG students, postdocs, ECRs and Group Leaders!
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Pradeepa Madapura @pradeepmadapura.bsky.social · 01/04/2025
Chromatin & transcription meeting is back again. Register your interest here www.biochemistry.org/events-and-t...
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Andrew Holding @andrewholding.bsky.social · 02/04/2025
Was a please to be hosted for a Seminar today. Fantastic team at the Lowy doing great work on fighting children’s cancer. Lots of ideas for follow up!
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Dave Daveson @davemayhem.bsky.social · 21/03/2025
ScienceSky I'm putting up a signal. I'm working on a new series of Horrible Science for Children's BBC. We would love to chat to experts about their favourite science facts for kids. I'm looking to chat to chemists first as well as some peeps who know their human biology.
media.tenor.com
a person is waving their hand in front of a sign that says " please help me "
Alt: a person is waving their hand in front of a sign that says " please help me "
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Andrew Holding @andrewholding.bsky.social · 24/03/2025
Post a ship that’s not Star Wars or Star Trek.
media.tenor.com
a computer generated image of a glowing object in a dark space
Alt: a computer generated image of a glowing ship in a dark space
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Lewis Dartnell @lewisdartnell.bsky.social · 24/03/2025
Helen has put together this wonderful list of all science festivals in the UK over the year.
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Andrew Holding @andrewholding.bsky.social · 11/03/2025
Just had to evacuate Kings Cross St Pancras underground. It was then most British evac. Everyone just queued as normal, and stood on the right of the escalator as minority of us used the left to walk up. No idea what was going on.
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Andrew Holding @andrewholding.bsky.social · 11/03/2025
I’m closing social media for today.
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Andrew Holding @andrewholding.bsky.social · 07/03/2025
I really like this article, it does a good job seperating out motivational stress and toxic stress, www.nature.com/articles/d41... to support people in a competative enviroment.
nature.com
‘I was told to toughen up’: is academia getting resilience all wrong?
Being repeatedly told to bounce back and develop a thicker skin can mask a toxic lab culture.
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Andrew Holding @andrewholding.bsky.social · 06/03/2025
🔴 Live #Science, #AMA and #Puzzles. Join me as we catch up on Science news, take on Baldur's Gate 3, mumble about what interests us and try to answer any science questions you have, live in chat! #Twitch #SciComm #SciStream www.twitch.tv/andrewholding @mattpt55.bsky.social @spannersready.bsky.social
twitch.tv
AndrewHolding - Twitch
[UK/USA] Science co-stream AMA, raising money to fight Cancer and playing Baldur's Gate 3 - ACT3!
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Andrew Holding @andrewholding.bsky.social · 06/03/2025
This is an amazing example of great scicomm, on a question I never thought to ask.
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Dr Jamie Gallagher @jamiebgall.co.uk · 27/02/2025
Soft-launch: I’ll be looking for science speakers at the Star Trek convention in August. Get dreaming and I’ll open applications in a few weeks.
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Andrew Holding @andrewholding.bsky.social · 27/02/2025
Our weekly Cambridge 105 show where Spanner's puts me on the spot to know all of science....
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Spanners @spannersready.bsky.social · 27/02/2025
Spanners and Dr Andrew bring back creatures lost to time!! open.spotify.com/episode/7h4W...
open.spotify.com
Back From the Dead
Cambridge Science · Episode
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Andrew Holding @andrewholding.bsky.social · 24/02/2025
When politicians are vocal on how UK economy struggles with low productivity. I find moments like this frustrating. I’m standing at a platform having to wait 30 mins for the next train, because it’s £100 more to get this half empty one, and no bus is reliable enough to leave for the station later.
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Andrew Holding @andrewholding.bsky.social · 19/02/2025
Who’s running a genomics starter pack for Sally?
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EMBL-EBI @ebi.embl.org · 17/02/2025
📢 We’re looking for a new Team Leader! @enasequence.bsky.social is recruiting a Team Leader to shape the strategy and direction for the ENA and Biosamples open data resources. Interested?👇
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Daniela Barillà @danielabarilla.bsky.social · 16/02/2025
Please consider signing this letter to the Royal Society if you have not signed already. docs.google.com/forms/d/e/1F... Over 2400 scientists have signed. #microsky #archaesky #astrosky 🧪🦠🧫🔭
docs.google.com
Open letter to the President of the Royal Society – time to stand up for your values
If you wish to show your support for the letter below regarding apparent inaction by the Royal Society in the face of breaches of its code of conduct by Elon Musk FRS, please sign below. I invite anyo...
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Stephen Curry @scurry.bsky.social · 14/02/2025
Tally just ticked past 1900 signatures. Please keep spreading the word about the letter & asking people to sign. It's important to make the Royal Society aware (at their meeting on 03 March) just how much the scientific community wants them to speak up for their values. forms.gle/SfsDemyS8QhP...
forms.gle
Open letter to the President of the Royal Society – time to stand up for your values
If you wish to show your support for the letter below regarding apparent inaction by the Royal Society in the face of breaches of its code of conduct by Elon Musk FRS, please sign below. I invite anyo...
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Andrew Holding @andrewholding.bsky.social · 15/02/2025
Apparently I owe a mint set of stamps bought it 1984… sent to me around my birthday that year.
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Andrew Holding @andrewholding.bsky.social · 28/01/2025
End of an era....
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Andrew Holding @andrewholding.bsky.social · 21/01/2025
Congratulations to Jodie, her paper is out in BMC Genomics identifying robust RT-qPCR reference genes for studying changes in gene expression in response to hypoxia in breast cancer. Great working with her, Will & @bridgekatherine.bsky.social on this. link.springer.com/article/10.1... 1/2
link.springer.com
Identification of robust RT-qPCR reference genes for studying changes in gene expression in response to hypoxia in breast cancer cell lines - BMC Genomics
Hypoxia is common in breast tumours and is linked to therapy resistance and advanced disease. To understand hypoxia-driven breast cancer progression, RT-qPCR is a widely used technique to quantify tra...
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Andrew Holding @andrewholding.bsky.social · 17/01/2025
That explains Walter White’s results.
media.tenor.com
a man in an apron is holding a wooden spoon over a pan of blue liquid .
ALT: a man in an apron is holding a wooden spoon over a pan of blue liquid .
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Anh Thy BUI @atbchem.bsky.social · 17/01/2025
Sometimes column chromatography gives you very nice surprises! 🧪 Charles's compound came out pure and bright 💎💙 Happy #FluorescenceFriday 🦋!
A test tube containing a blue fluorescent solution where huge bright crystalline needles have grown.
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Andrew Holding @andrewholding.bsky.social · 16/01/2025
🔴 Live Now! Kicking off the year with BG3 Act 3, science news, and live Q&A! 🧬 Join the stream for some #SciComm, puzzles, and gaming fun. Ask your science questions in chat! 📺 twitch.tv/andrewholding
twitch.tv
Twitch
Twitch is the world
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Andrew Holding @andrewholding.bsky.social · 15/01/2025
Announcing a second round to apply for our fully funded PhD opportunity at the University of York! Funded by @ukri.org / BBSRC. Our project focuses on understanding how low oxygen levels (hypoxia) change the way the hormone oestrogen works in breast cancer. www.findaphd.com/phds/project...
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Andrew Holding @andrewholding.bsky.social · 25/12/2024
I just finish wrapping presents to my wife… so in time. The fact this isn’t time stamped 00:00 is my typing speed.
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Andrew Holding @andrewholding.bsky.social · 12/12/2024
🌌 🧪Live on Twitch with @mattpt55.bsky.social Tonight topics: 1️⃣ Levitating spheres measuring nuclear decay: physicsworld.com/a/physicists... 2️⃣ The 5th person cured of HIV: abcnews.go.com/Health/5th-p... 3️⃣ Plus, back into Baldur’s Gate 3! 🔗 twitch.tv/andrewholding
physicsworld.com
Physicists detect nuclear decay in the recoil of a levitating sphere – Physics World
Principle of momentum conservation makes it possible to "see" individual alpha particles leaving a micron-scale silica bead
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Andrew Holding @andrewholding.bsky.social · 06/12/2024
Well, my office is stopping me getting diabetes.
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Bluesky @bsky.app · 03/12/2024
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
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John Bull @garius.bsky.social · 03/12/2024
This is ace. I've written (in a transport context) about agglomeration and how poorly thought out Treasury investment criteria make it worse. This helps highlight why London is a funding sponge. The UK has no proportionate second city in population terms to drag the needle on the dial away.
Line diagram of the UK showing a huge population spike in London vs elsewhere.
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Andrew Holding @andrewholding.bsky.social · 03/12/2024
I do love York, but can’t deny that exchanging the rain for this view wouldn’t be tempting. They even have some Roman city walls too.
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Andrew Holding @andrewholding.bsky.social · 02/12/2024
Interesting paper on the timing of CDK4/6 inhibitors use for patients and how it impacts outcome. www.nature.com/articles/s41...
nature.com
Early versus deferred use of CDK4/6 inhibitors in advanced breast cancer - Nature
The phase 3 SONIA trial challenges the benefits of using cyclin-dependent kinase 4 and 6 inhibitors as a first-line compared with second-line treatment.
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Andrew Holding @andrewholding.bsky.social · 01/12/2024
Are you up for some Sunday afternoon science communication? If so, I'm live on www.twitch.tv/tinytoxictofu to discuss my science and my research, come drop in and join the chat.
twitch.tv
TinyToxicTofu - Twitch
TofuTechTalk with @andrewholding about Cancer Research ❤ !tofutechtalk !pp
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Cahir O'Kane @cahirokane.bsky.social · 29/11/2024
Come and join us! Four (yes 4) new positions as Associate Prof or Professor in @cambridgebiosci.bsky.social‬ in: -Evolutionary Genomics -Developmental Plasticity & Robustness -Infection and/or Immunity -Molecular & Cellular Biology Not involved in recruitment (AFAIK), but happy to discuss.
bio.cam.ac.uk
School of Biological Sciences strengthens commitment to
Four new academic positions have been launched in the School of Biological Sciences aiming to recruit outstanding scientists in areas of significant research importance: Associate Professor /
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Andrew Holding @andrewholding.bsky.social · 28/11/2024
Hello to all my new followers - as well as doing academic science, I also do SciComm!🚨 Live now! Thursday 8pm GMT 🚨 Join me on Twitch for some science chat, your burning questions, and a bit of gaming fun! 🎮🧬 Hop in and say hi 👉 twitch.tv/andrewholding #Science #Gaming #Twitch
twitch.tv
Twitch
Twitch is the world
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Andrew Holding @andrewholding.bsky.social · 27/11/2024
Already have so many ideas I want to try this method on.
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Mitch Guttman @mitchguttman.bsky.social · 27/11/2024
Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. www.nature.com/articles/s41...
nature.com
ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics
ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...
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Andrew Holding @andrewholding.bsky.social · 26/11/2024
Day 2 of BACR continues to be a wonderful event in Newcastle. Highly recommend! Great to catch up breast cancer researchers and patient advocates from across the UK & beyond. Looking forward to the next talks.
Image of BACR logo at research conference
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Andrew Holding @andrewholding.bsky.social · 25/11/2024
Dean as always talking much sense. As a parent, smart phones and the internet are an absolute bane but not without value either.
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Andrew Holding @andrewholding.bsky.social · 24/11/2024
Are you looking for PhD studentship? We're advertising a fully funded PhD project, get in touch if you're interested. The project focuses the effects of hypoxia in tumours on the oestrogen response in breast cancer. Details: www.findaphd.com/phds/project... #PhDLife #BCMS 🧪 Please Share.
findaphd.com
Elucidating the Mechanism of Hypoxic Reprogramming of the Estrogen Response. at University of York on FindAPhD.com
PhD Project - Elucidating the Mechanism of Hypoxic Reprogramming of the Estrogen Response. at University of York, listed on FindAPhD.com
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Nessa Carson @supersciencegrl.co.uk · 22/11/2024
😲
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Andrew Holding @andrewholding.bsky.social · 22/11/2024
Interesting feature if you have the right kind of content… Pretty sure I’m happy with my content being gone forever.
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Andrew Holding @andrewholding.bsky.social · 22/11/2024
Thank you to the 50+ who dropped in at some point. Even if you just lurked it’s great to have you along. I also apologise for how terrible I am at Baldur’s Gate 3.
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Andrew Holding @andrewholding.bsky.social · 21/11/2024
🌌 Live on twitch talking science 🎥 twitch.tv/andrewholding @mattpt55.bsky.social and I catch up on science news... 1️⃣ A new vaccine shows promise against aggressive breast cancer. Will this be a game-changer? medicine.washu.edu/news/vaccine... #scistream
twitch.tv
Twitch
Twitch is the world
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Andrew Holding @andrewholding.bsky.social · 20/11/2024
If you're at the University of York @uoylibrary.bsky.social have Created a university of York starter pack! bsky.app/starter-pack...
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Andrew Holding @andrewholding.bsky.social · 20/11/2024
Interesting read. Sounds like a very reasonable response to a genuine issue with a study. The outcome appears to be a more robust publication. retractionwatch.com/2024/11/20/r...
retractionwatch.com
‘Relieved’: BMJ retracts and replaces article on unexpected weight loss as a sign of cancer
Brian Nicholson The British Medical Journal has retracted an article examining when unexpected weight loss could be a warning sign of cancer after the authors found an error in their work. The jour…
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