iiinova — where your digital self keeps evolving

Reposted by Akil Merchant, MD

Arun Sharma @arunsharmaphd.bsky.social · 29/03/2025

The website for our new @cirmnews.bsky.social Organoid and Organ-Chip Shared Resources Lab is now live! We offer training, services, and shared equipment to support stem cell researchers across California. Take a look!🔬🧫 www.cedars-sinai.edu/health-scien...

cedars-sinai.edu

CIRM Organoid and Organ-Chip Shared Resources Laboratory

Explore the Organoid and Organ-Chip Shared Resources Lab at Cedars-Sinai, advancing basic research with cutting-edge tools, training and expertise.

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Reposted by Akil Merchant, MD

Andy Pekosz @andrewpekosz.bsky.social · 25/03/2025

I got the news this morning on two COVID related grants that were being terminated because its no longer seen as a research priority by Health and Human Services. My people have been given their notice. I have no words to express my feelings. www.nbcnews.com/health/healt...

nbcnews.com

CDC is pulling back $11B in Covid funding sent to health departments across the U.S.

“Now that the pandemic is over, the grants and cooperative agreements are no longer necessary," federal health authorities wrote to funding recipients this week.

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Reposted by Akil Merchant, MD

Jon Cohen @cohenjon.bsky.social · 25/03/2025

...a “pointless, ill-advised move that will hurt U.S. science and pandemic readiness,” says Charles Rice, a Nobel Prize–winning virologist at Rockefeller University www.science.org/content/arti...

science.org

Saying ‘pandemic is over,’ NIH institute starts cutting COVID-19 research

Grant terminations halt research on improving vaccinations and preventing future pandemics

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Reposted by Akil Merchant, MD

Itai Yanai @itaiyanai.bsky.social · 13/01/2025

Top 4 things to know about doing science: 1. You need to have someone you can talk to 2. One-on-one discussions are the best 3. Think about discussions as improvisations and use the ‘yes, and’ rule 4. Create a safe space so both of you feel open to saying seemingly silly things

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Reposted by Akil Merchant, MD

The Dunn School, Oxford @dunnschool.bsky.social · 13/01/2025

A new paper by @tcell.bsky.social and team makes important advances towards improving CAR-T technology! Read the paper here: www.biorxiv.org/content/10.1... Listen to Omer talking about the paper and his spin-out company MatchBio here: podcasts.ox.ac.uk/series/immun...

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Reposted by Akil Merchant, MD

Science Magazine @science.org · 10/01/2025

Scientists have identified functional differences between human and mouse PD-1, which could impact preclinical research on cancer immunotherapies. Read more in #ScienceImmunology:

scim.ag

Functional differences between rodent and human PD-1 linked to evolutionary divergence

A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.

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Reposted by Akil Merchant, MD

Elizabeth McKenna @elizsmckenna.bsky.social · 07/01/2025

Now online in Cancer Discovery: Effects of an Initial Anti-CD19 CAR T-cell Therapy on Subsequent Anti-CD22 CAR T-Cell Manufacturing and Clinical Outcomes in Patients with Relapsed/Refractory LBCL by Yi-Jiun Su, Matthew Frank, and colleagues doi.org/10.1158/2159... @stanfordmedicine.bsky.social

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Reposted by Akil Merchant, MD

Hannah Isles @hannah-isles.bsky.social · 14/12/2024

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

science.org

Asparagine availability controls germinal center B cell homeostasis

Asparagine metabolism is a critical regulator of germinal center B cell function.

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Reposted by Akil Merchant, MD

Jonathan Hammer-Slay (Halloween '26 edition)👻🎃🧛🦇🔪 @jhammersley.bsky.social · 10/12/2024

Not sure who made this & when but fittingly came across it in my downloads folder today:

meme showing ma looking at 2145661(1) PDF file while other girl named 2145661.PDF looks on angrily

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Reposted by Akil Merchant, MD

Mark A. Hanson @hansonmark.bsky.social · 19/11/2024

The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on? direct.mit.edu/qss/article/... A 🧵 1/n #AcademicSky #PhDchat #ScientificPublishing #SciPub

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Reposted by Akil Merchant, MD

[toyota carroll] (6,5,,) @iamtherog.com · 23/11/2024

I think this could heal the partisan divide

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Akil Merchant, MD @amerchant.bsky.social · 22/11/2024

Nice work. PTCY for the win once again.

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Akil Merchant, MD @amerchant.bsky.social · 19/11/2023

Ok, so far it seems like the Bluesky algorithm thinks I want to see pictures of pets. I use social media mostly to keep up with what's new in science. Specificallly, lymphoma, tumor immunology, spatial profiling. Can folks suggest accounts to follow?

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