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Reposted by Yavuz Yazicioglu

Seth Thomas Scanlon @immunoeditor.bsky.social · 14/12/2024

This week in #Science #Immunology: a fantastic paper on #GerminalCenter #BCell #immunometabolism! Check it out!

Reposted by Yavuz Yazicioglu

Hannah Isles @hannah-isles.bsky.social · 14/12/2024

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

science.org

Asparagine availability controls germinal center B cell homeostasis

Asparagine metabolism is a critical regulator of germinal center B cell function.

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Yavuz Yazicioglu @yfy1.bsky.social · 13/12/2024

Thrilled to share our latest work on how the non-essential amino acid #asparagine metabolically regulates germinal centers. Huge thanks to my PhD supervisor @ajclarke.bsky.social, colleagues, and collaborators at the @ndorms.bsky.social @ox.ac.uk and @crick.ac.uk www.science.org/doi/10.1126/...

science.org

Asparagine availability controls germinal center B cell homeostasis

Asparagine metabolism is a critical regulator of germinal center B cell function.

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