Journal of Clinical Immunology - The sarcoma (Src) family of non-receptor tyrosine kinases (SFKs) regulate innate immunity through their roles in signal transduction and cell migration, adhesion...

AbstractObjective. To evaluate the diagnostic yield of whole exome sequencing (WES) vs targeted gene panel (TGP) testing in patients evaluated for autoinfl

Exciting announcement: National Eczema Society announce the four winners of their first research grant. Two PhD and two pump-priming projects

GeneticScores.org provides tools and data to help AI developers and human health researchers make better polygenic scores

Nature Immunology - Gain-of-function variants in the gene encoding NLRP3 lead to constitutive inflammasome activation and excessive IL-1β production. In this resource, authors perform...

Job Title: Communications and Social Media OfficerWorking For: European Animal Research AssociationLocation: London, with international travelSalary: This is a full-time position, salary £31,000–£35,0...

Research Assistant (Fixed Term) in the Department of Medicine at the University of Cambridge.

A new study shows that some of our cells favor genes of one parent or the other and can explain a longstanding mystery of why some people with disease-causing genes experience no symptoms.

TLR7 has been shown to promote inflammatory autoimmunity. Here the authors investigate whether changes in RNA structure affect TLR signaling and show that a TLR7 binding lncRNA Lnc-Atg16l1 promotes de...

Mutations in the RHO GTPase CDC42 have been associated with autoinflammatory diseases. In this study, the authors investigate how two distinct mutations, which trap CDC42 in the Golgi apparatus, are s...