iiinova — where your digital self keeps evolving

Reposted by Alfie Wearn

Alfie Wearn @alfiewearn.bsky.social · 10/03/2026

Neuromodulatory neurons are extremely susceptible to stress. I argue that their fragility is an inherent weak point, the breaking of which directly leads to Alzheimer’s Disease. I discuss this idea and its implications in a recently published perspective piece: dx.doi.org/10.1002/alz....

dx.doi.org

The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis

Sporadic Alzheimer's disease (AD) is associated with numerous risk factors, yet its precise cause remains unclear. Here, we describe a novel framework for AD pathogenesis, whereby diverse risk factor...

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Alfie Wearn @alfiewearn.bsky.social · 10/03/2026

dx.doi.org

The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis

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Heidi Jacobs @heidijacobslab.bsky.social · 21/01/2026

The Neuromodulatory Subcortical Systems PIA within @istaart.bsky.social is requesting nominations for the best paper of 2025 on neuromodulatory subcortical systems in Alzheimer's disease!! ISTAART members: promote the work of your colleagues (or yourself) here: alz.surveymonkey.com/r/Publicatio...

alz.surveymonkey.com

Publication of the Year Award - Nomination

Thank you for submitting your Nomination!

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Reposted by Alfie Wearn

The Transmitter @thetransmitter.bsky.social · 12/01/2026

Want to stay up to date on the latest developments in human neuroimaging research? Subscribe to the quarterly newsletter in partnership with the @ohbmofficial.bsky.social to receive news and announcements from both of our organizations: www.thetransmitter.org/newsletters-... #neuroskyence

thetransmitter.org

Newsletters and alerts

The latest news and perspectives on the neuroscience topics that interest you most, direct to your inbox

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Alfie Wearn @alfiewearn.bsky.social · 09/11/2025

We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo. We continue to show the value of structural MRI beyond simply measuring large-scale atrophy! Read here: ow.ly/1NvV50XkXnX

ow.ly

Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer’s disease pathology | PNAS

Hippocampal degeneration is a feature of both normal aging and Alzheimer’s disease (AD). Prior to macroscopic degeneration, microstructural changes...

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Reposted by Alfie Wearn

Proceedings of the National Academy of Sciences @pnas.org · 31/10/2025

The search for early signs of Alzheimer's disease continues: Brain scans reveal microstructural changes in the hippocampus that signal early stages of the disease, including demyelination, increased iron deposition, and changes in water content. In PNAS: ow.ly/1NvV50XkXnX

Heat maps for each of the five measures of structure mapped to the folded and unfolded surfaces of bilateral hippocampus, averaged across all participants. Cytoarchitectonic subfield boundaries are shown for reference.

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Reposted by Alfie Wearn

Kevin Sitek @sitek.bsky.social · 16/09/2025

Healthy scientific communities—built on open, engaged communication—are ready to take on the next challenges facing broader society. Had a blast writing this piece with @dupre.science and @alfiewearn.bsky.social. Many thanks to the other past @ohbm-com.com chairs for their feedback and support!

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Reposted by Alfie Wearn

The Transmitter @thetransmitter.bsky.social · 02/07/2025

Our award-winning news team is looking for an enthusiastic trade journalist to join our fast-paced newsroom in NYC. This is an excellent opportunity for a science journalist to develop a beat in the field of neuroscience. For more info, please visit: bit.ly/4nvAy4k #neuroskyence

simonsfoundation.wd1.myworkdayjobs.com

Reporter, The Transmitter

The Transmitter offers up-to-date news and analysis of the field of neuroscience and is dedicated to helping scientists at all career stages stay current and build connections. Our award-winning news ...

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Reposted by Alfie Wearn

Aperture Neuro @apertureohbm.bsky.social · 27/06/2025

In @ohbmossig.bsky.social's first Open Datasets Special Issue paper, Wearn et al. introduce the OHBM Time Machine, a freely accessible archive of Annual Meeting content on YouTube: doi.org/10.52294/001... @alfiewearn.bsky.social @sitek.bsky.social @sofievalk.bsky.social @stephforkel.bsky.social

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Alfie Wearn @alfiewearn.bsky.social · 25/06/2025

#OHBM2025 ! Let's chat about how noradrenergic system health influences brain network segregation. Poster #0916 today and tomorrow (Wed-Thurs) See you there this afternoon!

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 13/06/2025

Last chance to sign up to a Communications Competition at #OHBM2025! Choose from: 📊 A Best Figure Competition 🗣️ 3-Minute Chalk Talk Competition ⭐ See here for more details, or to sign up for one or both competitions: forms.gle/HE8GUxWyYS4o...

forms.gle

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Reposted by Alfie Wearn

Vincent Breton-Provencher @handle.invalid · 02/06/2025

My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇 can-acn.org/postdoctoral...

can-acn.org

Postdoctoral position available in the Breton-Provencher Lab at Université Laval to study neuromodulatory systems and foraging behavior – Canadian Association for Neuroscience

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Reposted by Alfie Wearn

Gc Rox @gcrox.bsky.social · 23/05/2025

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 12/05/2025

Going to #OHBM2025 in Brisbane? We're accepting entries for *two in-person science communication competitions* at the annual meeting: 📊 A Best Figure Competition 🗣️ 3-Minute Chalk Talk Competition ⭐ See here for more details, or to sign up for one or both competitions: forms.gle/1X9ccz2vpsRQ...

forms.gle

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Reposted by Alfie Wearn

John Anderson 🇨🇦 @janderz8.bsky.social · 04/04/2025

I have an opening for a graduate student at @carleton.ca (Carleton University) in the Department of Cognitive Science for fall 2025. Project is a multimodal MRI study examining how Hearing Loss affects cognition in older adults - contact me with a CV if you’re interested & have relevant expertise!

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Reposted by Alfie Wearn

Mallar Chakravarty @mallarchak.bsky.social · 22/03/2025

There's a stream of excellent papers in @apertureohbm.bsky.social being published! Check them out: apertureneuro.org Submit your own +code +data +open science +imaging studies+ Quick turnaround, a devoted ed board, and lowest APC around. And you'll support @ohbmofficial.bsky.social share pls!

apertureneuro.org

Aperture Neuro

Enables a diverse approach to sharing and communicating high quality, community-based, open neuroscience research.

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Reposted by Alfie Wearn

Kelton Minor @keltonminor.bsky.social · 18/03/2025

There are days in life that shake you. I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University & academic career... 1/🧵

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Alfie Wearn @alfiewearn.bsky.social · 16/03/2025

I was privileged to collaborate with the brilliant Stéfanie Tremblay on her project, just published in Neurobiology of Aging: Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease bit.ly/3Rb3QWW

bit.ly

Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease

Early detection of pathological changes in Alzheimer's disease (AD) has garnered significant attention in the last few decades as interventions aiming…

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Reposted by Alfie Wearn

Anika Wuestefeld, PhD @anikawuestefeld.bsky.social · 28/02/2025

..and another one! 🤩 Join us for a great webinar in cooperation with the @istaart.bsky.social NSS PIA on studying neuromodulatory subcortical nuclei with multimodal MRI! 📅Date: April 9 - 10:00 am CT 💻Register here: alz-org.zoom.us/webinar/regi...

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Reposted by Alfie Wearn

Andrea Stocco @andreastocco.com · 03/03/2025

The network of Alzheimer's Disease Research Centers is one of the most amazing NIH projects of all time: 33 sites collaborating to fight Alzheimer's in the lab and in the clinic at the same time. All of it in turmoil because the new funding is blocked.

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Reposted by Alfie Wearn

BWJones @bwjones.bsky.social · 27/02/2025

By @katherinejwu.com "The NIH... supported 99 percent of the drugs approved in the U.S. from 2010 to 2019. The agency has had a hand in “nearly all of our major medical breakthroughs over the past several decades,” The NIH is in a struggle for its (and our) lives. This is existential to America:

theatlantic.com

Inside the Collapse at NIH

Administration officials pressured NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.

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Reposted by Alfie Wearn

L.D. Burnett @ldburnett.bsky.social · 09/02/2025

for pity’s sake, I am BEGGING university leaders to stop framing this issue in terms of what this will cost the university. people dont care! EXPLAIN WHAT THIS WILL COST THE PUBLIC: closed hospitals and clinics, skipped treatments, loss of access to experimental drugs, unemployment, recession

sreenshot from the new york times reporting that Stanford University’s provost is talking about how the loss of funding from national institutes of health funding will cost the university $160 million. that’s not the way to get this changed — the people think “stanford is rich; no big deal.” leaders need to talk about what this will cost the public

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 17/02/2025

New blogpost from our OHBM 2024 award winner series! 🧠 Dr. Rosanna Olsen @rosannaolsen.bsky.social, winner of the 2024 Diversity and Inclusivity Champion Award, reflects on her vision for a more inclusive scientific community. Read here: www.ohbm-com.com/blog/55ubbep...

ohbm-com.com

Interview with Dr. Rosanna Olsen, 2024 Winner of the Diversity & Inclusivity Champion Award — OHBM Communications

Author: Ashley Tyrer Editor: Simon R. Steinkamp

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 27/01/2025

To help you expand your brain mapping network here on Bluesky, we have initialized an OHBM Neurosalience Podcast starter pack! 🧠🦋 Please feel free to comment if we've missed you or others out. Listen to the Neurosalience podcast here: open.spotify.com/show/1d5umtP... go.bsky.app/7gDbeAm

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Reposted by Alfie Wearn

The Organization for Human Brain Mapping @ohbmofficial.bsky.social · 21/01/2025

⁉️Does an MRI scanner always need to be so powerful? To kick off the year 2025, we at Brain Bites share the work of @asorby_adams and @NeuroSpin_91 With Low-field MRI and High-field MRI www.ohbm-com.com/brain-bites 🧠 #OHBM #BrainBites

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Reposted by Alfie Wearn

Sylvain Baillet @sylvainbaillet.bsky.social · 17/01/2025

Our thoughts are with our @ohbmofficial.bsky.social colleagues in Los Angeles facing devastating fires. As for all members suffering around the globe, #OHBM stands with you, offering support and solidarity. Wishing everyone safety and strength in the New Year. humanbrainmapping.org/files/ChairL...

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Reposted by Alfie Wearn

The Organization for Human Brain Mapping @ohbmofficial.bsky.social · 18/12/2024

🚨 Due to an ongoing technical issue with our payment processor, the submissions will be allowed to be finalized with a "Pay Later" option. Your submission will be considered on-time, and the abstract fee will be settled later. We apologize for the inconvenience.

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Alfie Wearn @alfiewearn.bsky.social · 18/12/2024

Message from #OHBM Executive Office for anyone struggling to submit abstract, there should now be a Pay Later option, so you can submit and pay once the system is fixed.

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 16/12/2024

New blogpost of our OHBM 2024 award winner series! Dr. Vince Calhoun (@vcalhoun.bsky.social), winner of the 2024 Glass brain award winner reflects on his career, recent developments in neuroscience, and more. Read it here: bit.ly/4iFd8qJ

bit.ly

Interview with Prof. Vince Calhoun, 2024 Winner of the Glass Brain award — OHBM Communications

Author: Ashley Tyrer Editor: Audrey Luo, Elisa Guma, Kevin Sitek , Megan Sheppard, Simon R. Steinkamp

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Reposted by Alfie Wearn

Tim Behrens @behrenstimb.bsky.social · 09/12/2024

Quick reminder that Elsevier's share price has doubled in the past 5 years: www.relx.com/investors/sh...

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Reposted by Alfie Wearn

OHBM Communications Committee (ComCom) @ohbm-com.com · 09/12/2024

Don’t miss the new blogpost in our OHBM award winner series! Prof. Alex Fornito (@alexfornito.bsky.social), 2024 OHBM Mentor Award winner, shares his insights on mentorship, neuroscience, and more. Read it here: bit.ly/4f8Cdr9 Thanks to authors @audreycluo.bsky.social, @ashleytyrer.bsky.social

ohbm-com.com

Interview with Prof. Alex Fornito, 2024 Winner of the Mentor Award — OHBM Communications

Authors: Audrey Luo & Ashley Tyrer Editors: Elisa Guma, Kevin Sitek, & Simon R. Steinkamp

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Reposted by Alfie Wearn

Ariel Rokem @arokem.org · 28/11/2024

Grateful to the OHBM communications committee (curiously not yet here?) and particularly to @audreycluo.bsky.social for putting together this interview with yours truly: www.ohbm-com.com/blog/intervi..., in which I had the opportunity to hold forth on my educational motivations and philosophy

ohbm-com.com

Interview with Prof. Ariel Rokem, 2024 Winner of the Education Award — OHBM Communications

Dr. Ariel Rokem received the Organization for Human Brain Mapping (OHBM) Education in Neuroimaging Award at the 2024 annual meeting in Seoul, South Korea. Dr. Rokem is a Research Associate Profe...

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