iiinova — where your digital self keeps evolving

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Alicia Martin @genetisaur.bsky.social · 29/04/2026

📣 𝐖𝐞’𝐫𝐞 𝐡𝐢𝐫𝐢𝐧𝐠 𝐚 𝐩𝐨𝐬𝐭𝐝𝐨𝐜 𝐢𝐧 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 & 𝐬𝐭𝐚𝐭𝐢𝐬𝐭𝐢𝐜𝐚𝐥 𝐠𝐞𝐧𝐞𝐭𝐢𝐜𝐬! 🌍📈🧬 If you’re finishing a PhD (or know someone who is) and want to work on complex trait biology + 𝑟𝑒𝑎𝑙-𝑤𝑜𝑟𝑙𝑑 𝑖𝑚𝑝𝑎𝑐𝑡, read on 👇

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Nicholas Mancuso @nmancuso.bsky.social · 28/04/2026

Please share! The USC Department of Quantitative and Computational Biology is searching for a full-time, teaching-track faculty member for the teaching of QBIO undergraduate statistics and computational biology courses. usccareers.usc.edu/job/los-ange...

usccareers.usc.edu

Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

Learn more about applying for Full-Time, Teaching-Track Faculty Position in Quantitative and Computational Biology at USC

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Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 02/04/2026

how I feel when open science initiatives choose to publish in Nature

Batman breaking a firearm and saying, "This is the journal of the enemy. We do not need it. We will not use it."

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David A Knowles @davidaknowles.bsky.social · 02/04/2026

@nygenome.org is hiring Genomic AI Fellows! (fancy postdoc positions) If you're interested in working at the interface of AI and genomics in a great environment please apply at: jobs.silkroad.com/NYGenome/Car...

jobs.silkroad.com

NYGC Genomic AI Fellows - 101 Avenue of the Americas, 7th Floor, New York, New York - New York Genome Center

Find a career with New York Genome Center

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Alexander Arguello @alexander-arguello.bsky.social · 27/03/2026

The eugenic roots of human genetics is clear enough, but I learned evolutionary biology at the turn of the century and I don’t recognize this straw man neo-Darwinism. lareviewofbooks.org/article/euge...

lareviewofbooks.org

Eugenics and the Modern Synthesis, Part II | Los Angeles Review of Books

For the Legacies of Eugenics series, Jessica Riskin continues to explore how the neo-Darwinian ‘modern synthesis’ was simply nonsense.

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Haky Im @hakyim.bsky.social · 26/03/2026

We're Hiring! Computational Biologist / Genomic Data Scientist. Join our lab to use cutting-edge data & AI/ML to advance human health. - Genetics & Genomics analysis - AI/ML in biology - Solving real-world genomic problems 📄 Full details: docs.google.com/document/d/1...

docs.google.com

Job-computational-biologist-2025.docx

Genomic Data Scientist / Computational Biologist We are looking to hire a lifelong learner interested in developing statistical and computational tools to sift through large amounts of data to make di...

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Abdel Abdellaoui @dr-appie.bsky.social · 10/03/2026

If you're looking to build or deepen your knowledge in statistical genetics, the ISG Workshop (June 1–11) covers the full range: biometrics, GWAS, polygenic scores, causal inference, and more. Open to all levels, virtual, and international: www.colorado.edu/ibg/workshop... Retweets appreciated 🙏

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Alexander Arguello @alexander-arguello.bsky.social · 13/02/2026

This is a revealing passage. I’ll amend the quote from Kevin in a non controversial way. “there is a dog genome, which contains—in an inescapable, deterministic way—the outcome of producing a dog.” The question is 1) how and, relatedly, 2) why you never get the same dog from the same dog genome.

You can find it clutched in the tiny fist of the sperm homunculus: in other words, nowhere.
The idea of the genetic blueprint is "a sort of neo-preformation," neurogeneticist Kevin Mitchell of Ireland's Trinity College Dublin told me. Nobody is arguing anymore that dogs have puppies instead of kittens because dog embryos contain tiny, preformed dogs, Mitchell says. Nevertheless, the blueprint metaphor still asserts that, in its place, "there is a dog genome, which contains—in an inescapable, deterministic way—the outcome of development.

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The Onion @theonion.com · 15/12/2025

How To Keep Your Christmas Tree Fresh theonion.com/how-to-keep-your-chris…

Perform Sap Infusions From Younger Trees: Regular infusions of sap from a more youthful spruce can reverse your tree’s biological age to that of a seedling.

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Mariah Hoye @mariahhoye.bsky.social · 19/11/2025

New #NIH prize competition to identify areas of biomedical science that can benefit from replication and to recognize past replication efforts to further promote the importance of research replication: www.challenge.gov?challenge=re... Submission deadline is in one month!

challenge.gov

Challenge.gov

Challenge.gov is the official government website supporting prize challenges and prize competitions that are sponsored by the US federal government. Here federal agencies provide prize awards to publi...

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Molly Przeworski @mollyprz.bsky.social · 14/11/2025

SAVE THE DATE: the yearly NY Population Genetics meeting will be back on March 9 2026, generously hosted by the @simonsfoundation.org. Details to follow. Please RT.

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Alexander Arguello @alexander-arguello.bsky.social · 07/11/2025

JOB POSTING: Director, National Human Genome Research Institute hr.nih.gov/careers/open...

hr.nih.gov

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Graham Coop @gcbias.bsky.social · 15/10/2025

We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT

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Hakhamanesh Mostafavi @hakha.bsky.social · 14/10/2025

I’ll be attending #ASHG25! I’m currently hiring for (i) a Senior Research Scientist or (ii) a Postdoc position in my lab. If you’re interested, please reach out to arrange a time to meet and discuss.

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Stephen Turner @stephenturner.us · 25/09/2025

My colleague @hernmoral.bsky.social is teaching what looks like a wonderful course online this November - Museomics: An Introduction to Genomic Analyses of Natural History Collections. Register: www.physalia-courses.org/courses-work... #consgen

physalia-courses.org

Museomics: An Introduction to Genomic Analyses of Natural History Collections

3-7 November To foster international participation, this course will be held online

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Alexander Arguello @alexander-arguello.bsky.social · 24/09/2025

“mRNA vaccines seem to work—I think they’ve been great! I am amazed at how much public policy seems to ignore how great these vaccines are (of course, there are great vaccines that aren’t mRNA-based, too).” febs.onlinelibrary.wiley.com/doi/10.1111/...

febs.onlinelibrary.wiley.com

FEBS Press

Anthony Letai is Professor in Medicine at Harvard Medical School and Dana Farber Cancer Institute, and President of The Society for Functional Precision Medicine. Among Tony’s scientific achievements...

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Adam Phillippy @aphillippy.bsky.social · 22/09/2025

Delighted to finally announce a preprint describing the Q100 project! “A complete diploid human genome benchmark for personalized genomics” For which we finished HG002 to near-perfect accuracy: www.biorxiv.org/content/10.1... 🧵[1/14]

biorxiv.org

A complete diploid human genome benchmark for personalized genomics

Human genome resequencing typically involves mapping reads to a reference genome to call variants; however, this approach suffers from both technical and reference biases, leaving many duplicated and ...

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Torsten Günther @trstngnthr.bsky.social · 17/09/2025

I have funding for a 2-year dry-lab postdoc to join our team @humanevouu.bsky.social 🧪 (Deadline Oct 21st) The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations). Please share! www.uu.se/en/about-uu/...

uu.se

Postdoctoral position in Population Genomics - Uppsala University

Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University

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Alexander Arguello @alexander-arguello.bsky.social · 05/09/2025

Best of luck to the brave soul who would like to be the next Director of the National Institute of Mental Health hr.nih.gov/jobs/search/...

hr.nih.gov

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Alexander Arguello @alexander-arguello.bsky.social · 09/08/2025

Yes, science works. Can science work better? Also yes.

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Richard McElreath 🐈‍⬛ @rmcelreath.bsky.social · 09/07/2025

How can we reform science? I have some ideas. But I am not sure you’ll like them, because they don’t promise much. elevanth.org/blog/2025/07...

elevanth.org

Which Kind of Science Reform

What hope is there for science reform, if we can't agree on what to reform? Right now, principles are more important than practices.

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Alexander Arguello @alexander-arguello.bsky.social · 11/07/2025

In science there are fears that some research areas or questions will be misinterpreted, exploited, and weaponized by bad actors. One solution offered is to avoid these topics altogether lest we add fuel to ideological fire.

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Alexander Arguello @alexander-arguello.bsky.social · 23/06/2025

Last week the National Advisory Council for Human Genome Research met and approved a new initiative: ancient DNA for Modern Genomics (aDMG). You can watch the presentation and discussion here at the 1:54:00 mark. videocast.nih.gov/watch=56826

Photo of the skeletal remains of a man buried about 8000 years ago in Turkey (Photo credit: JACOB ROODENBERG)

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no. @joles.bsky.social · 05/05/2025

applying for jobs again

screenshot from an online job application form. the question reads "Can you describe specific ways you have integrated AI tools into your development workflow? Please include any custom setups, automations, or use cases beyond single prompt usage" (a red asterisk indicates that this is a required question).

an answer has been typed in the textbox below the question:

"there is a monster in the forest and it speaks with a thousand voices. it will answer any question you pose it, it will offer insight to any idea. it will help you, it will thank you, it will never bid you leave. it will even tell you of the darkest arts, if you know precisely how to ask.

it feels no joy and no sorrow, it knows no right and no wrong. it knows not truth from lie, though it speaks them all the same.

it offers its services freely to any passerby, and many will tell you they find great value in its conversation. “you simply must visit the monster—i always just ask the monster.”

there are those who know these forests well; they will tell you that freely offered doesn’t mean it has no price

for when the next traveler passes by, the monster speaks with a thousand and one voices. and when you dream you see the monster; the monster wears your face."

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Jonathan Pritchard @jkpritch.bsky.social · 01/06/2025

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

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Andrea Ganna @andganna.bsky.social · 01/06/2025

We have 2-3 group leader positions opening @fimm-uh.bsky.social !! We are looking for outstanding candidates in human genetics and precision medicine. This time we have a focus on population health data science. E.g. AI for EHR/health data Generous starting package 💰 shorturl.at/FAk6n

jobs.helsinki.fi

FIMM-EMBL Group Leaders in Molecular Medicine

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Mariah Hoye @mariahhoye.bsky.social · 05/05/2025

📢 Calling all early-career scientists who have promoted enhanced research rigor: The deadline for the NINDS Early-Career Rigor Champions prize has been extended to 6/6/25! Describe your efforts in six short prompts for your chance to win a CASH prize of up to $10k! Up to 11 awards will be made!

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Human Pangenome Reference Consortium @humanpangenome.bsky.social · 12/05/2025

📢 HPRC Release 2 is here! Now with phased genomes from 200+ individuals, a 5x increase from Release 1. Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️: humanpangenome.org/hprc-data-re...

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Alex Strudwick Young @alextisyoung.bsky.social · 28/04/2025

I am recruiting a quantitative/computational postdoc to my group at UCLA. This is a great opportunity to work on foundational theory, methods, and software in statistical genetics. Link to apply: recruit.apo.ucla.edu/JPF10275. Please repost!

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Alexander Arguello @alexander-arguello.bsky.social · 08/04/2025

21st century technology. 18th century taxonomy.

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Alexander Arguello @alexander-arguello.bsky.social · 24/03/2025

Reading “The usefulness of useless knowledge” by Abraham Flexner, founding director of the Institute for Advanced Study. Writing in 1939, this passage stood out:

The subject which I am discussing has at this moment a peculiar poignancy.
In certain large areas-Germany and Italy especially-the effort is now being made to clamp down the freedom of the human spirit. Universities have been so reorganized that they have become tools of those who believe in a special political, economic, or racial creed.
Now and then a thoughtless individual in one of the few democracies left in this world will even question the fundamental importance of absolutely untrammeled academic freedom. The real enemy of the human race is not the fearless and irresponsible thinker, be he right or wrong. The real enemy is the man who tries to mold the human spirit so that it will not dare to spread its wings, as its wings were once spread in Italy and Germany, as well as in Great Britain and the United States.

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Chris Gunter 🧬 @girlscientist.bsky.social · 18/11/2024

Are you a (or do you know a) recent college graduate who wants to work in human genetics and genomics? Applications are open for the ASHG-NHGRI Post-Baccalaureate Genomics Analyst Fellowship! Great chance to understand how grants and societies work AND get paid. www.ashg.org/careers-lear...

ashg.org

ASHG-NHGRI Post-Baccalaureate Genomics Analyst Fellowship

This is a fellowship program designed for recent undergraduates to gain exposure to and training in multiple career paths that advance public service for human genetics and genomics

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Alexander Arguello @alexander-arguello.bsky.social · 14/11/2024

From 2002: “Former NIH directors Harold Varmus and Bernadine Healy told the [congressionally appointed] committee… that Congress could make the NIH more effective by reorganizing it into clusters.” www.nature.com/articles/418...

nature.com

Future of the NIH may lie in restructuring, committee told - Nature

Nature - Future of the NIH may lie in restructuring, committee told

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Alexander Arguello @alexander-arguello.bsky.social · 08/11/2024

not sure I like praising someone’s achievements by noting they have published “in very well known journals.” praise me for my careful, thoughtful, and creative work!

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Alexander Arguello @alexander-arguello.bsky.social · 26/10/2023

Looking forward to lots of good science and well deserved awards at #ASHG23 next week. Happy to talk about the genetics of complex traits, funding opportunities at NHGRI, and biological reductionism and the philosophy of causation 🙃

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Alexander Arguello @alexander-arguello.bsky.social · 06/10/2023

How do genetic and non-genetic factors shape trait variation in people? How do these factors act across scales of biological organization? Register for NHGRI’s workshop - Advances in the Genetic Architecture of Complex Human Traits. Thurs 16th - Fri 17th Nov nih.zoomgov.com/webinar/regi...

Interdependencies across scales of biological, social, and ecological organization may confound modern-day genetic association studies limiting their interpretation and application both within and between individuals, families, and populations. Large-scale genetic, genomic, and phenotypic data now provide an opportunity to develop novel approaches that embrace and leverage this real-world complexity and improve our understanding of phenotypic variation. Covariances among biological, social, and geographical effects may be used to better delineate how genetic and non-genetic factors contribute to health-and disease-related trait variation and disparities. The goal of this workshop is to provide historical context, build on the current state of the field, identify gaps and emerging opportunities, and to develop a framework for future research directions in the genetics of complex traits, from cells and tissues to individuals and populations.

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Alexander Arguello @alexander-arguello.bsky.social · 02/10/2023

using a single word, complete the following sentence: Hearts pump, guts digest, and brains _____.

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Alexander Arguello @alexander-arguello.bsky.social · 26/09/2023

funding opportunity: NHGRI is seeking R01/R21 applications to develop novel theory and methods for understanding the genetic architecture of complex human traits grants.nih.gov/grants/guide...

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

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