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Alexandre Djiane

@adjiane.bsky.social
757 followers 546 following 29 posts

Group Leader at IRCM (Montpellier, France) working on Epithelial Growth and Cancer A lot of Drosophila, a little bit of Mouse Growth, Cell signalling, Inter-organ communications

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Alexandre Djiane @adjiane.bsky.social · 25/01/2026
Extremely beautiful!
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Alexandre Djiane @adjiane.bsky.social · 26/11/2025
BRAVO!!!!!!! So well deserved.
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Oded Rechavi @odedrechavi.bsky.social · 15/10/2025
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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University of Cambridge @cam.ac.uk · 07/10/2025
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: bit.ly/4mM8o3r
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EDRC2025 @edrc2025.bsky.social · 28/09/2025
We have had a great final morning at #EDRC2025 with three fantastic keynote lectures by Maria Gambetta, Tor Erik Rusten and Silke Sachse
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EDRC2025 @edrc2025.bsky.social · 25/09/2025
3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!
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Development @dev-journal.bsky.social · 22/09/2025
Read the article ‘Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions’ here: doi.org/10.1242/dev....
doi.org
Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions
Highlighted Article: Localization of the cell-adhesion molecule Sidekick to tricellular adherens junctions requires specific extracellular domains and its intracellular binding partner, the PAK4 kinas...
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Alexandre Djiane @adjiane.bsky.social · 15/09/2025
Congratulations! So Sunday notifications are good. Nice! My experience is that Friday notifications just before WE or holidays are bad, really bad...
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Hadi Boukhatmi @muscleflylab.bsky.social · 30/08/2025
Our new preprint is out ! We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles. Check it out and please share @igdrennes.bsky.social
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Alexandre Djiane @adjiane.bsky.social · 29/08/2025
BTW, same goes for grant reviews...
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Alexandre Djiane @adjiane.bsky.social · 29/08/2025
Shame on the reviewers to be that lazy and disrespectful. I had similar suspicion with another publisher. Some claims of the reviewers were completely wrong. Discussed with editors about the issues without actually calling them AI generated. Is there a way to prove it was AI generated?
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Alexandre Djiane @adjiane.bsky.social · 14/08/2025
But it is a fraction of the price, and extremely robust (ours is a shared equipment for the institute).
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Alexandre Djiane @adjiane.bsky.social · 14/08/2025
My point is it is great to count objects and have a pretty picture with less background and blur (even though confocal remains way better), but I would be extremely cautious for intensity quantification.
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Alexandre Djiane @adjiane.bsky.social · 14/08/2025
We use it daily on Drosophila tissues. It gives pretty images, but it remains epifluorescence (more bleed through) and one must remain extremely careful with the "levels" seen on the screen.
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Alexandre Djiane @adjiane.bsky.social · 11/08/2025
Bravo!
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Alexandre Djiane @adjiane.bsky.social · 17/07/2025
After manuscript reviews full of inaccuracies which appear AI generated, and final grant rejection (despite excellent reviews), I will let the disappointment and anger pass, and will not review your manuscript tonight. I apologise for the potential delay, but you might thank me later.
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Alexandre Djiane @adjiane.bsky.social · 12/07/2025
Great ressource!
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jakbosch.bsky.social @jakbosch.bsky.social · 11/07/2025
I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️. Thread below🧵 1/8 www.biorxiv.org/content/10.1...
biorxiv.org
Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking
Secreted proteins regulate many aspects of animal biology and are attractive targets for biomarkers and therapeutics. However, comprehensively identifying the "secretome", along with their tissues of ...
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Alexandre Djiane @adjiane.bsky.social · 05/07/2025
That is a tough one to beat... But sometimes it is better these obviously bitter reviews that can be dismissed with the editors (once you have let the anger pass), than those who want to kill your paper by asking an endless list of unfeasible experiments (to which editors rarely, hum never, say no)
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Alexandre Djiane @adjiane.bsky.social · 23/06/2025
Congratulations!
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fly paper broadcast @fly-broadcast.bsky.social · 04/06/2025
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis #Drosophila
pubmed.ncbi.nlm.nih.gov
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis #Drosophila
PubMed link
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Lucas Waltzer @lucaswaltzer.bsky.social · 03/06/2025
#drosophila @flybase.bsky.social request emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate! www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Dmitri Petrov @petrovadmitri.bsky.social · 03/06/2025
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
philanthropy.cam.ac.uk
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
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Alexandre Djiane @adjiane.bsky.social · 24/05/2025
At the end of a seminar part of an interview process, after 15 minutes of question and a good exchange waiting to be last to talk: "What you propose is exactly what not to do..."
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Levayer Lab @levayerr.bsky.social · 21/05/2025
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision www.biorxiv.org/content/10.1...
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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · 15/05/2025
📣 Junior PI Opportunity Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰 450k€ package | Drosophila, RNA, immunity IBMC + Labex NetRNA network 📅 Apply by June 30, 2025 🔗 ibmc.cnrs.fr/en/laboratoi... #RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
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Alexandre Djiane @adjiane.bsky.social · 13/05/2025
PS: would be very interested to have your feed back on the specificity of these TRE / mRE-DsRed in muscles. Thanx
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Alexandre Djiane @adjiane.bsky.social · 12/05/2025
In our hands, even the control mutant mRE-DsRed were becoming pinkish with age. We used them for reporting JNK activity only in imaginal discs, where it was specific.
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Alexandre Djiane @adjiane.bsky.social · 08/05/2025
Congrats!
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Andreas Prokop @poppi62.bsky.social · 10/04/2025
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
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MaraverLab @maraverlab.bsky.social · 03/04/2025
Thrilled to present our study aiming to identify new vulnerabilities in lung cancer: www.biorxiv.org/content/10.1... Joining forces from mouse genetics, thoracic oncology, metabolism, and AlphaFold fields we dissected the role of a largely unknown but essential protein in cancer, FMO4.🧵
biorxiv.org
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Rita Rebollo @ritarebollo.bsky.social · 27/03/2025
Hi! Here is a PhD opportunity at Montpellier, IGH institute with Séverine Chambeyron to study endogenous retroviruses ! #TEsky #PhD
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Collège des Sociétés savantes académiques de France @societes-savantes.fr · 08/03/2025
Retour en images sur le discours notre président Patrick Lemaire lors du rassemblement #StandUpForScience #7Mars devant l'opéra Comédie à 18h à #Montpellier où nous étions nombreux, en plus des 4 rassemblements du midi
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Guillaume Bossis @guillaumebo6.bsky.social · 07/03/2025
We keep standing up for Sciences in Montpellier @standupforscifr.bsky.social
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Bardin Lab @bardinlab.bsky.social · 04/03/2025
Stand Up for Science France protest this Friday March 7. Numerous actions throughout France including a protest march in Paris starting at Jussieu 13h30 by @sufs-paris-rp.bsky.social @standupforscience.bsky.social 👉 standupforscience.fr #StandUpForScience #StandUpForScienceFrance
standupforscience.fr
Stand Up For Science France | Le 7 mars, nous défendons les sciences – parce que les sciences sont un bien commun.
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Inserm @inserm.fr · 25/02/2025
L’Inserm rejoint Bluesky ! Découvrez ici toutes les actualités de la recherche médicale menée par l’Inserm, pour la santé de toutes et tous.
Image décorative.
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@bilderlab @bilderlab.bsky.social · 25/02/2025
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details. (1/5)
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Alexandre Djiane @adjiane.bsky.social · 23/02/2025
Parc de Sceaux?
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@MEmilieTerret @memilieterret.bsky.social · 20/02/2025
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact. www.science.org/doi/10.1126/...
science.org
Noninvasive characterization of oocyte deformability in microconstrictions
A microfluidic measurement method translates oocyte mechanical characterization into oocyte quality assessment.
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Alexandre Djiane @adjiane.bsky.social · 13/02/2025
Would be interested as well. Please let me know.
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Nadine Laguette @nadinelaguette.bsky.social · 05/02/2025
Check out our most recent preprint where we describe Mecp2 as a régulatrice of cGAS-STING associated signaling. 🧪🔥
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The Company of Biologists @biologists.bsky.social · 04/02/2025
Our latest extraordinary biologist is Sarah Bray, Chair of our Board of Directors. To learn more about Sarah's role and relationship with @biologists.bsky.social, read this interview in @dev-journal.bsky.social: bit.ly/3CEibaX. #100biologists @uniofcam.bsky.social
The Company of Biologists 100 logo to the left and QR code to the right.
 
Portrait of Sarah Bray to the left, text to the right
 
100 extraordinary biologists

Sarah Bray

Sarah Bray is the current Chair of the Board, having been a Director since 2016 and a Professor at the University of Cambridge, UK with a research interest in Notch signalling.

#100biologists #biologists100
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Christophe 🔬 Leterrier @christlet.bsky.social · 31/01/2025
Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed
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Alexandre Djiane @adjiane.bsky.social · 30/01/2025
Next stop, La Sainte Chapelle.
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flymuscles @flymuscles.bsky.social · 15/01/2025
I'm going ask my kids to make the Drosophila for me.
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Kasia Siudeja @ksiudeja.bsky.social · 03/01/2025
To kick start the New Year, I'm delighted to share the lab's first preprint - now online: biorxiv.org/cgi/content/... See below for a couple of highlights👇 Any feedback is welcome! "TEsky" HAPPY NEW YEAR to everyone! 🥂
biorxiv.org
An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobility
Retrotransposons, multi-copy sequences that propagate via copy-and-paste mechanisms involving an RNA intermediate, occupy large portions of all eukaryotic genomes. A great majority of their manifold c...
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The Interactive Fly @interactivefly.bsky.social · 23/12/2024
Hermant, C., Matias, N. R., Michel-Hissier, P., Huynh, J. R., Mathieu, J. (2024). Lethal Giant Disc is a target of Cdk1 and regulates ESCRT-III localization during germline stem cell abscission. Development, 151(8) journals.biologists.com/dev/article/...
journals.biologists.com
Lethal Giant Disc is a target of Cdk1 and regulates ESCRT-III localization during germline stem cell abscission
Summary: Redundancy between Lgd and Alix, and coordination with the cell cycle kinase Cdk1, confers robust and timely abscission of Drosophila germline stem cells.
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Levayer Lab @levayerr.bsky.social · 21/12/2024
Looking for a job still connected to acamedia and research ? Do you like interacting with a lot of people, outreach activity, organising scientific events ? Do you have good writing and organisation skills ? We may have a job for you👇 (permanent position) emploi.pasteur.fr/offre-de-emp... 🙏RT
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Alexandre Djiane @adjiane.bsky.social · 22/12/2024
Félicitations!
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