Scientists have long debated the origins of exceptional human achievements. This literature review summarizes recent evidence from multiple domains on the acquisition of world-class performance. We re...

Cell biology; Organizational aspects of cell biology; Specialized functions of cells; Functional aspects of cell biology

One simple exercise proved older adults can build and retain muscle – and caused a paradigm shift in science

Drugs that can prevent or relieve migraine attacks are only effective for some people. Research is starting to untangle the reasons why.

The cell surface is a dynamic interface that controls cell-cell communication and signal transduction relevant to organ development, homeostasis and repair, immune reactivity, and pathologies driven b...

Mechanisms that differentiate the capacity of newborn immune cells to orchestrate tissue regeneration are inadequately understood. Lantz et al. discover that in response to dying cells, neonatal macro...

CD47 is expressed by viable cells to protect against phagocytosis. CD47 is recognized by SIRPα, an inhibitory receptor expressed by macrophages and other myeloid cells. Activated SIRPα recruits SHP-1 ...