When conventional cardiopulmonary resuscitation (CCPR) cannot restore spontaneous circulation, the initiation of venoarterial extracorporeal membrane oxygenation during refractory cardiac arrest—known...

The VA ECMO Registry of Germany (VERGE, http://va-ecmo-register.de/ ) is a prospective, multicenter, investigator-driven registry of Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) all-come...

Purpose The evidence supporting the benefit on clinical outcomes of prone positioning during veno-venous extracorporeal membrane oxygenation (V-V ECMO) for acute hypoxemic respiratory failure remains ...

Thoracic aortic aneurysm (TAA) is characterized by dilation of the aorta. In this Primer, Berger et al. review the epidemiology, pathophysiological mechanisms, diagnosis and management of TAA, and provide insights into its effect on quality of life and suggestions for areas of future research.

Rettkowski, Romero-Mulero et al. show that myocardial infarction impacts bone marrow haematopoietic stem cells and leads to inflammatory myelopoiesis, which can be dampened by treatment with 4-oxo-ret...

Notfallreform - how to? Warum wir genau jetzt über die Notfallversorgung sprechen müssen · Episode

Fibrosis is a key characteristic of a range of chronic diseases that has been challenging to target with drugs. This Review highlights core pathways active in fibrotic conditions across organs, as wel...

Background New postoperative atrial fibrillation (POAF) occurs in about 40% after cardiac surgery. Mineralocorticoid receptor antagonists (MRA) are known to reduce chronic atrial fibrillation (AF) dev...

Including Nobel laureates, climate researchers, and parents of kids saved by groundbreaking drugs.

Abstract figure legend Illustration of cellular and molecular cross-talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cell....

Achim Lother, Dawid Staudacher; Inotropes and mortality in patients with cardiogenic shock: more questions than answers, European Heart Journal - Cardiovas

This editorial refers to ‘Hypokalaemia in patients with type 2 diabetes and chronic kidney disease: the effect of finerenone—a FIDELITY analysis’, by B. Pi

Aging is a complex process characterized by biological decline and a wide range of molecular alterations to cells, including changes to DNA methyla...

Cardiogenic shock (CS) is a medical emergency with high in-hospital mortality. New biomarkers are needed to identify patients at a greater risk of adv…

Several trials have evaluated diuretic-based strategies to improve symptoms and outcomes in patients with acute heart failure (AHF). The authors sough…

A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of car...