iiinova — where your digital self keeps evolving

Abhinav Sur @abhinavsur.bsky.social · 13/08/2026

Super happy to see this work out in @genesdev.bsky.social. It was a lot of fun working on this project with my postbac Ella Segal and @jeffreyafarrell.bsky.social.

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Maxwell Shafer @maxshafer.bsky.social · 02/06/2026

Have you ever wondered if fish yawn? (and if they do, what that tells us about yawning?) The first preprint from the lab and a serendipitous observation ⬇️ www.biorxiv.org/content/10.6...

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Abhinav Sur @abhinavsur.bsky.social · 12/05/2026

After spending 6 amazing years at NIH, the Sur Lab opens its doors at the University of Arizona @uazbio5.bsky.social. We study development, function, and communication networks of rare intestinal cell types using zebrafish and human organoids. Check out more at: sites.arizona.edu/surgutchatte...

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Zebrafish Rock! @zebrafishrock.bsky.social · 03/05/2026

Frugal design, previously demoed at @devbioquintay.bsky.social 🐟🌎

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Abhinav Sur @abhinavsur.bsky.social · 02/05/2026

Great initiative! @zebrafishrock.bsky.social helped me recruit members of my new lab by promoting my job posting.

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Zebrafish Rock! @zebrafishrock.bsky.social · 02/05/2026

Looking for candidates with #zebrafish experience? Let us promote your job openings across our Slack, LinkedIn & Bluesky network! To use this FREE service, fill out the Google Form on our website: linktr.ee/zebrafishrock #RockOn 🧪

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Abhinav Sur @abhinavsur.bsky.social · 01/05/2026

What a ride this has been with @jeffreyafarrell.bsky.social!! THANK YOU JEFF for giving me the best 6 years of my life doing science in your lab. I'm finding it extremely hard to say this goodbye! I will miss everyone in the Farrell Lab and especially YOU! 🥹🥹

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Abhinav Sur @abhinavsur.bsky.social · 27/03/2026

📢📢 My lab at the University of Arizona is opening soon and I'm RECRUITING — especially techs/specialists with interest in aquaculture or zebrafish husbandry. Please share! 🏔️ 🌵 Lab website: lnkd.in/eZHk8DxA Apply/more info: arizona.csod.com/ux/ats/caree... #zebrafish #husbandry #aquatic #marine

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Andy Baxevanis @baxevanislab.bsky.social · 12/03/2026

📢 We've just published a chromosome-level nuclear and mitochondrial genome assembly for Capitella teleta (~243.6 Mb). Despite a highly conserved gene family repertoire, both genomes show extensive rearrangements, revealing a decoupling of gene family and chromosomal evolution.

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Genome Biology and Evolution @genomebiolevol.bsky.social · 12/03/2026

Davies et al. assemble the genome of polychaete Capitella teleta, a model for evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology, generating a 243 Mb chromosome-level genome, and publish a genome browser. 🔗 doi.org/10.1093/gbe/evag041 #genome #evolution

GBE | A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta

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Abhinav Sur @abhinavsur.bsky.social · 05/03/2026

I had a lot of fun working on this collaboration and revisiting the scRNAseq data. Although I work on zebrafish now, I still haven't forgotten my spiralian roots. Thanks @chemamd.bsky.social @baxevanislab.bsky.social and Elaine Seaver for the opportunity.

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Zebrafish Rock! @zebrafishrock.bsky.social · 28/02/2026

Today is #RareDiseaseDay & we are celebrating by highlighting the invaluable work of the Undiagnosed Diseases Network (UDN)! Formed in 2020, it aims to solve the most challenging medical mysteries using advanced technologies. In this thread, we will highlight their use of the #zebrafish model. 1/5 🧪

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John F. Rawls @jfrawls.bsky.social · 12/02/2026

Happy International Day of Women & Girls in Science! Today & everyday I am grateful for the opportunity to work alongside & learn from this talented group of women scientists. Funded by grants from the NIH, this team is working to understand how the gut microbiome affects our digestive health.

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Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 11/02/2026

Switching fields or wanting to become an expert in #zebrafish research? The @mblscience.bsky.social 2026 Zebrafish Development & Genetics course offers a fantastic opportunity to learn from leaders in the field! Application deadline: March 2 Please spread the word! www.mbl.edu/education/ad...

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Abhinav Sur @abhinavsur.bsky.social · 07/02/2026

A very well deserved award for a wonderful scientist and mentor. My time in Jeff’s lab has undoubtedly been one of the most enjoyable and enlightening periods in my scientific career.

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Jeff Farrell @jeffreyafarrell.bsky.social · 09/01/2026

Happy New Year! NEW LAB PREPRINT testing how best4+ intestinal epithelial cells develop! best4+ cells are conserved across vertebrates and altered in IBD & colorectal cancer. But they were first molecularly IDed in 2019. We barely know anything about them yet! What do they do?? HOW DO THEY GET MADE?

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Abhinav Sur @abhinavsur.bsky.social · 22/12/2025

Closing out 2025 with our new preprint where @jeffreyafarrell.bsky.social and I explore development and function of zebrafish intestinal best4+ cells – molecularly described in 2019, conserved in evolution, absent in 🐭, and altered in inflammatory bowel disease. www.biorxiv.org/content/10.6...

biorxiv.org

Developmental regulation of intestinal best4+ cells

best4+ /CFTR-high expressing cells are a recently described intestinal epithelial cell type potentially altered in inflammatory bowel disease and colorectal cancer. However, their developmental origin...

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auroralkraus.bsky.social @auroralkraus.bsky.social · 18/11/2025

Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish." lnkd.in/gN7z6th4

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Abhinav Sur @abhinavsur.bsky.social · 26/10/2025

I am delighted to announce that I will be starting as an Assistant Professor at the University of Arizona in Spring 2026. Our lab will study intestinal best4+ cells in zebrafish. We are seeking a lab manager with previous zebrafish experience – come build with us. surlab-gastro.my.canva.site

surlab-gastro.my.canva.site

Home

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Jeff Farrell @jeffreyafarrell.bsky.social · 31/07/2025

Ok, friends! If you’re a Daniocell user, it’s now available again outside of the NIH. Very sorry for any inconvenience this posed for any of you and thanks for your patience. We’re taking additional steps to hopefully prevent similar outages in the future. Happy surfing 🎣

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Development @dev-journal.bsky.social · 28/07/2025

Transitions in development – an interview with Jeffrey Farrell @jeffreyafarrell.bsky.social talks about becoming a group leader, his insights on advocacy for developmental biology and his belief in unifying single-cell biology with classical approaches. journals.biologists.com/dev/article/...

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Abhinav Sur @abhinavsur.bsky.social · 14/06/2025

For more customized analysis using our zebrafish timecourse dataset available in Daniocell, check out this amazing resource DaniocellDesktop. Extremely happy to see this brainchild of @jeffreyafarrell.bsky.social out in the wild.

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EvoDevo PanAm @evodevopanam.bsky.social · 12/06/2025

Spiralia enthusiasts!! 🐚🐙🐌💛 Our amazing speaker for the Spiralia Satellite symposia at the #PASEDB2025 Néva Meyer, Associate Professor, Clark University Organizers: Christina Zakas and @albertinlab.bsky.social #evodevo #pasedb #spiralia

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Kristen Kwan @blockintheback.bsky.social · 21/05/2025

It was so awesome to have @jeffreyafarrell.bsky.social here to give a departmental seminar today!!

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Zebrafish Rock! @zebrafishrock.bsky.social · 10/05/2025

With a published genome & advancements in gene editing, the field of #zebrafish genetics has exploded in recent decades. We take a look back at major achievements in this infographic. For more, read this book chapter by @varshneylab.social et al (2015)($) doi.org/10.1016/bs.a... #ZebrafishFunFacts 🧪

Timeline of important technological developments in zebrafish research.

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Zebrafish Rock! @zebrafishrock.bsky.social · 10/05/2025

Masters of regeneration? #Zebrafish are capable of regenerating their fins, spinal cord, pancreas, skin, retina, heart, liver, brain, tendons, hair cells, & kidney. For more info on this amazing species, read this primer on regeneration: journals.biologists.com/dev/article/... #ZebrafishFunFacts 🧪

Organ regeneration in the zebrafish. Summary of some of the organs and tissues used for regeneration studies in zebrafish. Preferred injury models are annotated for each organ. Image and text credit to Marques et al. (2019) https://doi.org/10.1242/dev.167692

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Elizabeth Beston @elizabethbeston.bsky.social · 10/05/2025

I thought this was an interesting interaction! This Polychaete larva (possibly Spionidae?) has somehow got inside the tube of a Lanice sp. (sand mason worm) larva! The tube resident doesn’t seem too fussed about the visitor though. 🦑 #plankton

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Katherine W. Rogers @katwrog.bsky.social · 21/04/2025

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

biorxiv.org

An optogenetic toolkit for robust activation of FGF, BMP, and Nodal signaling in zebrafish

Cell signaling regulates a wide range of biological processes including development, homeostasis, and disease. Accessible technologies to precisely manipulate signaling have important applications in ...

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Zebrafish Rock! @zebrafishrock.bsky.social · 16/04/2025

“These findings support the use of zebrafish as a useful comparative model for studying the meninges, provide a foundational description for future zebrafish meningeal research” New work from @biomarina-vg.bsky.social & Weinstein Lab at NIH 🐟

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Siegenthaler Lab @siegenthalerlab.bsky.social · 20/04/2025

Great new work led by @biomarina-vg.bsky.social on zebrafish meninges! Particularly 🤩 is the descriptions of ependymin-expressing meningeal cells (not a fibroblast!) & ablation studies showing their essential role in viability. So much more to learn! Congrats Marina & team on this great work! 🦓🐟🧠

Adult zebrafish possess complex multilayered cephalic meninges. Transmission electron micrograph (TEM) images of transverse sections through the dorsal heads of adult zebrafish, at the level of the optic tecta. A, Pseudocolored overview image of the cephalic meninges, revealing multiple tissue layers between the skull and the brain parenchyma. B, Dorsal surface of a dissected adult zebrafish brain, showing the leptomeninges partially peeling away from the underlying brain parenchyma. C, Higher magnification image of the boxed region in panel B, showing multiple leptomeningeal cell layers separated by membrane bilayers (red arrowheads), delimited ventrally by a well-defined basal lamina (pseudocolored purple). D, Nucleated red blood cell-containing blood vessel embedded within the leptomeninges, with desmosomes and junctions connecting individual endothelial cells (arrows). E, Higher magnification image of the boxed region in panel D, showing a portion of the vessel wall with a characteristic endothelial cell-cell junction (arrow). F, Higher magnification image of collagen fibers in the adult zebrafish leptomeninges. G, Pseudocolored overview image of the cephalic meninges, showing separated heavily pigment dura mater (dural meninges) and leptomeninges. multiple tissue layers (pseudocolored) between the skull and the brain parenchyma. H, Higher magnification image of the boxed region in panel G, showing bilayered dural meninges with periosteal dura adjacent to the skull with an underlying meningeal dural cell layer with numerous large melanophore pigment granules (arrows). Scale bars = 3 µm (A), 4 µm (B,G), 1 µm (C,H), 2 µm (D), 0.3 µm (E), and 0.2 µm (F).

M, Dorsal view of an adult casper zebrafish head with the optic tectum and cerebellum clearly visible through the thin, translucent skull. The yellow box shows the approximate region depicted in panels N and O. N,O, Confocal images of the meninges imaged through the intact skull of a living Tg(mrc1a:egfp)y251, Tg(epd:mcherry)y715 double transgenic adult zebrafish, showing (N) mrc1a:egfp-positive FGPs and lymphatics (green) and epd:mcherry-positive LBCs (magenta), or (O) only epd:mcherry-positive LBCs (magenta). P, High-resolution, high magnification confocal Z-stack through the leptomeninges on the surface of a dissected Tg(mrc1a:egfp)y251, Tg(epd:mcherry)y715 double transgenic adult zebrafish brain, showing LBCs (magenta) and FGPs (green). The large center image is a dorsal XY view of the reconstructed image stack, and the images below and to the right show single-plane XZ and YZ views along the planes noted by the dashed lines (xz-1, xz-2, yz).

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Jeroen Bakkers @bakkerslab.bsky.social · 03/01/2025

🫀 Zebrafish protein unlocks dormant genes for mammalian heart repair. Our work published by @springer1842.bsky.social in Nature CVR uncovers how the protein HMGA1 could unlock mammalian heart repair. rdcu.be/d5owa #HeartHealth #Regeneration #Biomedicine #Cardiology

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David Schoppik @schoppik.com · 30/12/2024

Closing out the year, @cbellegarda.bsky.social and @franziau.bsky.social argue that zebrafish have much to teach us about diversity. Well, diversity among motor neurons that move the eyes, anyway 👀. Plus read our opinionated takes on current articles too! authors.elsevier.com/a/1kL%7Eb3Q9...

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Development @dev-journal.bsky.social · 30/12/2024

Signal timing determines transfating outcomes Read this Research Highlight showcasing work from Alejandro Berrio, David McClay @duke-university.bsky.social and colleagues: journals.biologists.com/dev/article/...

Figure 5 (A) Top: Mid-sagittal sections of control embryos at 14, 16 and 21 hpf. Skeletogenic cells are labeled green by the hybridization chain reaction (HCR) targeting msp-130, blastocoelar cells labeled yellow with HCR targeting astacin4, and pigment cells labeled red with HCR targeting pks1. Bottom: Micromereless embryos at the same three time points and stained with the same HCR probes.

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Jeff Farrell @jeffreyafarrell.bsky.social · 26/11/2024

Out now in Dev Cell! scRNAseq trajectories describe the cascade of gene expression as cells differentiate, but turning them into a clear understanding of the underlying biology of a cell type's development remains challenging. authors.elsevier.com/c/1k9qj5Sx5g... (1/)

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