The Earlham Institute was awarded a Flexible Talent Mobility Award (FTMA) from BBSRC – designed to facilitate short-term exchanges between academic or industrial institutions – to place two…

In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...

Chemla et al. review the release of bacteria into the environment and propose engineering strategies to help improve performance and reduce risk.

We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to insert recombination handles into re...

The cell-free protein synthesis (CFPS) system, as a technical core of synthetic biology, can simulate the transcription and translation process in an …

Smith et al. engineered a “turn on” fluorescent biosensor (dubbed “PancACe”) for acetyl-CoA from a fusion of the proteins PanZ and circularly permuted GFP. PancACe measures changes in acetyl-CoA level...

Rubisco is the main entry point of inorganic carbon into the biosphere and a central player in the global carbon system. Its relatively low catalytic constant as well as its tendency to also accept O2...

Rubisco is the main gateway through which inorganic carbon enters the biosphere, catalyzing the vast majority of carbon fixation on Earth. This pivotal enzyme has long been observed to be kinetically ...

Sustainability and artificial intelligence dominate our seventh annual round-up of exciting innovations.

Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...

Conjugative plasmids are the main vehicle for the spread of antimicrobial resistance (AMR) genes in clinical bacteria. AMR plasmids allow bacteria to survive antibiotic treatments, but they also produ...

Menace sanitaire croissante considérée comme une priorité de santé, les infections dues à des bactéries résistantes aux antibiotiques pourraient tuer 1,28 million de personnes dans le monde en 2030. F...

The programming of multicellular processes for biological computation requires increasingly complex genetic circuit design. Through automated circuit design, it is now possible to systematically break...

Iridia Inc., the pioneering molecular data technology company, announces the successful launch of its groundbreaking mission to send cryptocurrency and archival data to the surface of the moon. In thi...

DNA-based storage platform provider Catalog Technologies has delivered the first commercially available book encoded into DNA.

From corn to bananas, farmers stand to gain from cultivating edited crops that are resilient and sustainable, paired with precision insecticides and microbe engineering. But reaching those with the gr...

The Science and Technology Committee urges urgent policy actions across Government to maximise the contribution of engineering biology to the UK economy and public services.