iiinova — where your digital self keeps evolving

Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 16/12/2025

This year we partnered with Automata to combine our #genomics expertise with state-of-the-art #labautomation. Check out Automata's latest article featuring our Head of Technical Genomics, @drkarimgharbi.bsky.social about implementing our new integrated platform.

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Breaking Barriers in Genomics: Earlham Institute and Automata Redefine Lab Automation

Pioneering a New Era in Genomic Research with Scalable, Intelligent Automation. Read more now.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 14/10/2025

💬 “This work demonstrates the power of technology to reveal novel biology, in this case hidden functional diversity which had not been documented before." - @drkarimgharbi.bsky.social Newly-discovered diversity in the #wheat #genome could improve one of the world’s most important staple #crops.

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New wheat diversity discovery could provide an urgently-needed solution to global food security

Newly-discovered diversity in the wheat genome could offer vital new opportunities to improve and ‘climate-proof’ one of the world’s most important staple crops.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 09/07/2025

Two of our students - Rosie and Archie - shared their experience working with our Technical Genomics and Earlham Biofoundry Groups, developing their skills and gaining practical training in #genomics and #laboratory #automation. 🧬 🔗 buff.ly/KF08OL9 @drkarimgharbi.bsky.social @cgrandel.bsky.social

earlham.ac.uk

Developing the next generation of technical specialists with T-Levels

The Earlham Institute T-Level industry placement programme inspires the next generation of young people pursuing careers in science.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 09/07/2025

We're proud to support T Level Students at the Earlham Institute and a new report from @uk-itss.bsky.social today showcases the impact of industry placements for supporting young people to thrive in a range of scientific careers. 🥼 🔗 buff.ly/7JMmK1V? @tech-commit.bsky.social

itss.org.uk

T Level industry placements in higher education and research

Sector insights and practical guidance

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 26/06/2025

A great day with #Tecan bringing together those involved in lab #automation for #genomics to discuss the latest trends, considerations, and applications of this technology.

Attendees chatting in the Earlham Institute Atrium besides a display of scientific posters.

Attendees sitting in the conference room listening to one of the speakers who is not visible in the photo.

Manuela D'Agata, Head of Sales Development and Marketing at Tecan, stands in front of the presentation screen to introduce the day.

Senior Scientist Thomas Brabbs introduces his talk on overcoming hurdles of PacBio HiFi automation.

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Karim Gharbi @drkarimgharbi.bsky.social · 14/05/2025

Join us in Norwich for a day of automation goodness, including talks, lab tours, and more.

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Karim Gharbi @drkarimgharbi.bsky.social · 12/05/2025

Really nice work led by @conradn.bsky.social , and a prime example of how transformative technology can reveal new biology.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 29/04/2025

Great to see Group Leader Dr Wilfried Haerty (@whaerty.bsky.social) presenting his work at #PacBioPRISM this afternoon! Dr Haerty leads our #CellularGenomics research programme and is interested in the impact of variation on gene and transcript expression across scale. @pacbio.bsky.social

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Haerty Group - Comparative Genomics and Population Genetics

Investigating the evolution of functional noncoding sequences

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 28/02/2025

TALK: Interested in #genomics for #bioscience? Caoimhe Morley from @ucl.ac.uk will be joining us next month at our User Group meeting, to share her research on targeted #longread sequencing for somatic structural variant discovery in Multiple System Atrophy brains. Register to join 👇

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NBRI Transformative Genomics - Annual User Meeting

A one-day meeting of the bioscience community to hear the latest updates and applications from the BBSRC-funded National Bioscience Research Infrastructure in Transformative Genomics at the Earlham…

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 02/03/2025

🦠 Multidrug resistance in human fungal pathogens is a growing threat. Join Mat Fisher (@imperialcollegeldn.bsky.social) at the NBRI Transformative Genomics User Meeting as he explores the drivers behind this challenge. 📅 Registration closes tomorrow: buff.ly/3EUgAyx #Genomics #Sequencing

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 27/02/2025

Make sure you join our NBRI Transformative Genomics User Meeting to hear @conradn.bsky.social discuss how ultra-long read sequencing reveals patterns of replication site initiation across the human genome. Join us here 👉 buff.ly/4blYAJl #genomics #sequencing @drkarimgharbi.bsky.social

Graphic promoting the speakers at the NBRI Transformative Genomics User Group Meeting: Drivers of emerging multidrug resistance in human fungal pathogens by Mat Fisher, Imperial College London. Spatial transcriptomics reveals expression gradients in developing wheat inflorescences at cellular resolution, by Katie Long, John Innes Centre. Targeted long-read sequencing for somatic structural variant discovery in Multiple System Atrophy brains, by Caoimhe Morley, University College London. Ultra-long read sequencing resolves the pattern of replication site initiation across the human genome, byConrad Nieduszynski, Earlham Institute. Spatial transcriptomics and the ageing brain, by Aimée Parker, Quadram Institute.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 12/02/2025

💬 “By using a much-expanded set of robust barcodes, we can pool more samples in the sequencing lane, making better use of our capacity and further lowering the cost per sample.” - @drkarimgharbi.bsky.social LITE2 takes affordable genome sequencing to a new level

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LITE2: Reduced bias and increased throughput

The Earlham Institute's improved Low Input, Transposase Enabled (LITE) protocol is a low-cost method for high-throughput whole genome sequencing with reduced DNA input.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 05/02/2025

Technological advances have transformed #sequencing, but costs and timescales can still be limiting, especially in library generation. Earlham Institute's updated Low Input, Transposase Enabled (LITE) protocol offers low-cost, high-throughput whole #genome sequencing with reduced DNA input. 💻🧬🧪

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LITE2 takes affordable genome sequencing to a new level

The Earlham Institute's improved Low Input, Transposase Enabled (LITE) protocol is a low-cost method for high-throughput whole genome sequencing with reduced DNA input.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 16/01/2025

Catch our scientists at the #FestivalofGenomics later this month where they'll be discussing overcoming data challenges in #singlecell biology, and ultra #longread #sequencing in #DNAreplication.👇🧬🖥️ @flgenomics.bsky.social @drkarimgharbi.bsky.social @conradn.bsky.social @whatchamacaulay.bsky.social

Image promoting the Earlham Institute's participation at the Festival of Genomics and Biodata 2025, including details of two talks:

Iain Macaulay, Group Leader, participating in a panel discussion on 'Overcoming data challenges of high-resolution biology' on Thursday 30 January, from 16:05 to 17:05.

Karim Gharbi, Head of Technical Genomics, and Conrad Nieduszynski, Group Leader, will present a talk titled 'Ultra-long read sequencing resolves the pattern of DNA replication initiation across the human genome' on Thursday 30 January, from 16:35 to 17:05.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 09/01/2025

A new study in Scientific Data from the Earlham Institute, @rothamsted.bsky.social, @rbgkew.bsky.social, and @ergabiodiv.bsky.social presents a high-quality annotated orange foxtail grass #genome, shedding light on what makes it such an exceptional survivor in modern #crop systems. 🧬🖥️🌿

earlham.ac.uk

New sequenced genome sheds light on weed resistance

Genomic advances reveal how similar weeds can dominate wheat fields that are geographically separated by over 5,000 miles.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 25/11/2024

Huge thanks to @elinork.bsky.social for her brilliant talk about #comparative #genomics and the #Zoomomia project at today's inaugural Dame Janet Thornton Lecture. We were pleased to be joined by Prof Thornton to introduce the lecture. @neilhall.bsky.social @broadinstitute.org

Professor Dame Janet Thornton introducing Professor Elinor Karlsson.

Professor Neil Hall introducing today's lecture.

Professor Elinor Karlsson discussing her work on the Zoomomia project, with a large projection screen behind her displaying a cover of Science magazine.

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Reposted by Karim Gharbi

Earlham Institute @earlhaminst.bsky.social · 25/10/2024

Great to see this important resource published. The reference #genome was supported by @pacbio.bsky.social HiFi data generated through the Transformative Genomics National Bioscience Research Infrastructure at the Earlham Institute, led by @drkarimgharbi.bsky.social. nisd.ac.uk/new-grasspea...

nisd.ac.uk

New grasspea genome unlocks rapid climate-smart breeding

New grasspea genome has been published online, providing researchers with a new tool to unlocks potential for rapid climate-smart breeding

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